Predictors for Sensorineural Hearing Loss in Patients With Tubotympanic Otitis, Cholesteatoma, and Tympanic Membrane Retractions

2012 ◽  
Vol 33 (6) ◽  
pp. 934-940 ◽  
Author(s):  
Snezana Dragoljub Jesic ◽  
Ana Dragan Jotic ◽  
Borivoj Bogdan Babic
Keyword(s):  
Hearing Loss ◽  
Sensorineural Hearing Loss ◽  
Tympanic Membrane ◽  
Sensorineural Hearing

Otologic Manifestations of Wegener's Granulomatosis

1980 ◽  
Vol 88 (5) ◽  
pp. 586-593 ◽  
Author(s):  
Thomas V. McCaffrey ◽  
Thomas J. McDonald ◽  
George W. Facer ◽  
Richard A. DeRemee
Keyword(s):  
Hearing Loss ◽  
Sensorineural Hearing Loss ◽  
Tympanic Membrane ◽  
Middle Ear ◽  
Wegener’S Granulomatosis ◽  
Wegener's Granulomatosis ◽  
Tympanic Membrane Perforation ◽  
Sensorineural Hearing ◽  
Suppurative Otitis Media ◽  
Membrane Perforation

Review of 112 patients with Wegener's granulomatosis showed that 21 (19%) had ear involvement. Conductive deafness, which was present in all 21 patients, was due to serous middle ear fluid, suppurative otitis media with thickening of the tympanic membrane, perforation of the tympanic membrane, or granulation tissue in the middle ear space. Nine patients also had sensorineural hearing loss. Sensorineural hearing loss was improved in five of the nine patients after control of the disease with prednisone and cyclophosphamide.

scholarly journals Effects of Expansion on Consonant Recognition and Consonant Audibility

2009 ◽  
Vol 20 (02) ◽  
pp. 119-127 ◽  
Author(s):  
Marc Brennan ◽  
Pamela Souza
Keyword(s):  
Hearing Loss ◽  
Sensorineural Hearing Loss ◽  
Tympanic Membrane ◽  
Research Design ◽  
Hearing Aid ◽  
Sensorineural Hearing ◽  
Low Level ◽  
Low Intensity ◽  
Consonant Recognition ◽  
Speech Token

Background: Hearing aid expansion is intended to reduce the gain for low-level noise. However, expansion can also degrade low-intensity speech. Although it has been suggested that the poorer performance with expansion is due to reduced audibility, this has not been measured directly. Furthermore, previous studies used relatively high expansion kneepoints. Purpose: This study compared the effect of a 30 dB SPL and 50 dB SPL expansion kneepoint on consonant audibility and recognition. Research Design: Eight consonant-vowel syllables were presented at 50, 60, and 71 dB SPL. Recordings near the tympanic membrane were made of each speech token and used to calculate the Aided Audibility Index (AAI). Study Sample: Thirteen subjects with mild to moderate sensorineural hearing loss. Results: Expansion with a high kneepoint resulted in reduced consonant recognition. The AAI correlated significantly with consonant recognition across all conditions and subjects. Conclusion: If consonant recognition is the priority, audibility calculations could be used to determine an optimal expansion kneepoint for a given individual.

Audiologic and Otologic Clinical Manifestations of Loeys-Dietz Syndrome: A Heritable Connective Tissue Disorder

2021 ◽  
pp. 019459982110088
Author(s):  
Jun W. Jeon ◽  
Julie Christensen ◽  
Jennifer Chisholm ◽  
Christopher Zalewski ◽  
Marjohn Rasooly ◽  
...  
Keyword(s):  
Hearing Loss ◽  
Connective Tissue ◽  
Sensorineural Hearing Loss ◽  
Tympanic Membrane ◽  
Conductive Hearing Loss ◽  
Wide Spectrum ◽  
Clinical Manifestations ◽  
Connective Tissue Disorder ◽  
Sensorineural Hearing ◽  
Conductive Hearing

Objective Loeys-Dietz syndrome (LDS) is a rare genetic connective tissue disorder resulting from TGF-ß signaling pathway defects and characterized by a wide spectrum of aortic aneurysm, arterial tortuosity, and various extravascular abnormalities. This study describes the audiologic, otologic, and craniofacial manifestations of LDS. Study Design Consecutive cross-sectional study. Setting Tertiary medical research institute. Methods Audiologic and clinical evaluations were conducted among 36 patients (mean ± SD age, 24 ± 17 years; 54% female) with genetically confirmed LDS. Cases were categorized into genetically based LDS types 1 to 4 ( TGFBR1, TGFBR2, SMAD3, TGFB2, respectively). Audiometric characteristics included degree and type of hearing loss: subclinical, conductive, mixed, and sensorineural. Results LDS types 1 to 4 included 11, 13, 5, and 7 patients, respectively. In LDS-1, 27% had bilateral conductive hearing loss; 9%, unilateral mixed; and 36%, subclinical. In LDS-2, 38% had conductive hearing loss and 38% subclinical. In LDS-3 and LDS-4, 40% and 43% had bilateral sensorineural hearing loss, respectively. Degree of hearing loss ranged from mild to moderate. Bifid uvula was observed only in LDS-1 (55%) and LDS-2 (62%). Submucosal/hard cleft palates were primarily in LDS-1 and LDS-2. Posttympanostomy tympanic membrane perforations occurred in 45% (10/22 ears) of LDS-1 and LDS-2. There were 4 cases of cholesteatoma: 3 middle ear (LDS-1 and LDS-2) and 1 external ear canal (LDS-3). Conclusion Conductive hearing loss, bifid uvula/cleft palate, and posttympanostomy tympanic membrane perforation are more common in LDS-1 and LDS-2 than LDS-3 and LDS-4, while sensorineural hearing loss was present only in LDS-3 and LDS-4. These LDS-associated key clinical presentations may facilitate an early diagnosis of LDS and thus prompt intervention to prevent related detrimental outcomes.

Trends in Use and Timing of Intratympanic Corticosteroid Injections for Sudden Sensorineural Hearing Loss

2020 ◽  
pp. 019459982097617
Author(s):  
Michael C. Jin ◽  
Z. Jason Qian ◽  
Shayna P. Cooperman ◽  
Jennifer C. Alyono
Keyword(s):  
Hearing Loss ◽  
Sensorineural Hearing Loss ◽  
Tympanic Membrane ◽  
Cox Regression ◽  
Sudden Sensorineural Hearing Loss ◽  
Hazard Ratio ◽  
Sensorineural Hearing ◽  
Tympanic Membrane Perforations ◽  
Oral Corticosteroids ◽  
Corticosteroid Injections

Objective Oral corticosteroids are treatment mainstays for idiopathic sudden sensorineural hearing loss (SSNHL). Recent studies suggest that intratympanic (IT) steroid injections may be effective as an alternate or adjunctive therapy. We sought to investigate nationwide trends in treatment patterns for SSNHL. Study Design Retrospective cross-sectional study. Setting A large nationwide health care claims database spanning 2007 to 2016. Methods Patients with SSNHL were identified from the IBM Watson Health MarketScan Database. Multivariable logistic, linear, and Cox regression were used for demographic- and comorbidity-adjusted analyses. Results Overall, 19,670 patients were included. Between 2007 and 2016, use of oral corticosteroids alone decreased (83.6% to 64.6%, P < .001), while use of IT corticosteroids alone and combination IT-oral corticosteroids increased (IT only, 7.9% to 15.1%, P = .002; IT-oral, 8.5% to 20.4%, P < .001). During the study period, time to treatment initiation decreased for both administration modalities, though more dramatically for IT corticosteroids (IT, 124.0 to 10.6 days, P < .001; oral, 42.6 to 12.7 days, P < .001). In patients receiving both IT and oral corticosteroids, concurrent first-line use increased (25.2% to 52.8%, P < .001). Repeat injections have also become more common but may raise risk of persistent tympanic membrane perforations (vs no injection; hazard ratio [first injection] = 7.95, 95% CI = 5.54-11.42; hazard ratio [fifth or higher injection] = 17.47, 95% CI = 6.93-44.05). Conclusion SSNHL management increasingly involves early IT steroids as an alternative or adjunctive option to oral steroids. Use of repeat IT corticosteroid injections has also increased but may raise risk of persistent tympanic membrane perforations and subsequent tympanoplasty. Future decision analysis and cost-effectiveness studies are necessary to identify an optimal care pattern for SSNHL.

scholarly journals Gyermekkori otitis media serosa miatt tubussal ellátott betegek hosszú távú nyomon követése

2015 ◽  
Vol 156 (46) ◽  
pp. 1859-1864 ◽  
Author(s):  
Gabriella Fekete-Szabó ◽  
Fekete Kiss ◽  
László Rovó
Keyword(s):  
Hearing Loss ◽  
Sensorineural Hearing Loss ◽  
Tympanic Membrane ◽  
Otitis Media ◽  
Eustachian Tube ◽  
Sensorineural Hearing ◽  
Hearing Level ◽  
Tympanostomy Tube ◽  
Tube Insertion ◽  
Serous Otitis Media

Introduction: The authors report about the efficacy of inserted tympanostomy tube in children with serous otitis media. Aim: The aim of the authors was to assess the status of eardrum, the function of Eustachian tube and hearing level 10 years after the use of tympanostomy tube. Method: Patients filled up a questionnaire and microscopic examination of tympanic membrane, tympanometry, Eustachian tube function examination, and audiometry tests were performed. Results: In the period of 2003–2004, ventilation tube insertion was performed in 711 patients in the ENT Department of Pediatric Health Center of University of Szeged. In 349 patients adenotomy and tympanostomy tube insertion, in 18 cases tonsillectomy and grommet insertion and in 344 patients only typmanostomy tube insertion were performed. Due to objective difficulties (address change, no phone number) 453 patients were asked for control test and 312 persons accepted the invitation. Normal hearing level was found in 84.6% of patients and normal tympanometry result occurred in 82%. Tympanic ventilation disorder, perforation of tympanic membrane, sensorineural hearing loss and sensorineural hearing loss due to noise exposure were diagnosed. Conclusions: Application of tympanostomy tube is effective in the treatment of serous otitis media resulting from ventilation disorder. The authors draw attention to the importance of tympanometry examination to prevent the adhesive processes and cholesteatoma in chronic ventilation disorder of the middle ear. Orv. Hetil., 2015, 156(46), 1859–1864.

Potential ototoxicity from triamcinolone, neomycin, gramicidin and nystatin (Tri-Adcortyl™) cream

2005 ◽  
Vol 119 (1) ◽  
pp. 48-50 ◽  
Author(s):  
S P Thomas ◽  
J R Buckland ◽  
S R Rhys-Williams
Keyword(s):  
Hearing Loss ◽  
Sensorineural Hearing Loss ◽  
Tympanic Membrane ◽  
Tympanic Membrane Perforation ◽  
Sensorineural Hearing ◽  
Ear Canal ◽  
Membrane Perforation ◽  
Perforated Tympanic Membrane

Although rare, ototoxicity from the use of aminoglycoside drops is well recognized. Ototoxicity has not been described with the use of combination aminoglycoside-steroid-antifungal creams or ointments. We present the case of a 60-year-old man with a perforated tympanic membrane who suffered a total hearing loss after the instillation of cream containing triamcinolone, neomycin, gramicidin and nystatin (Tri-Adcortyl™ cream) into his ear canal. On balance, we believe that a number of potentially ototoxic constituents in this cream were responsible. Other possible causes of sensorineural hearing loss and the possible mechanisms of ototoxicity of this cream are discussed. The reasons why such creams may be particularly ototoxic, compared with drops, are also considered. The authors caution against the use of such creams or ointments in the ear if there is any suspicion of a tympanic membrane perforation.

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