scholarly journals Effects of Relative Blood Volume???Controlled Hemodialysis on Blood Pressure and Volume Status in Hypertensive Patients

ASAIO Journal ◽  
2007 ◽  
Vol 53 (3) ◽  
pp. 357-364 ◽  
Author(s):  
Judith J. Dasselaar ◽  
Roel M. Huisman ◽  
Paul E. de Jong ◽  
Johannes G. M. Burgerhof ◽  
Casper F. M. Franssen
1976 ◽  
Vol 51 (s3) ◽  
pp. 211s-213s
Author(s):  
M. Ulrych ◽  
Z. Ulrych

1. Relationships between labelled albumin disappearance rate (LADR), plasma volume, blood volume, plasma renin activity (PRA) and blood pressure (BP) were studied in normotensive control subjects and patients with hypertension of different aetiology and severity. In essential hypertensive patients without complications an inverse linear relationship was found between blood pressure and plasma or blood volume. 2. Very close inverse correlations were found between LADR and PRA in both normotensive subjects and patients with uncomplicated essential hypertension. LADR appears to be an excellent reference standard for PRA. 3. It is postulated that LADR mainly reflects the relation between circulating fluid and vascular capacitance tone. LADR is increased in hypertension and blood volume may still be inappropriately high.


Circulation ◽  
2020 ◽  
Vol 142 (Suppl_3) ◽  
Author(s):  
Shantum Misra ◽  
brian P lucas

Background: In patients with congestive heart failure administration of an intravenous diuretic results in increased urine production and, depending on the volume status, an immediate change in relative blood volume (RBV). Changes in RBV are already applied clinically to monitor fluid removal and better guide diuresis in patients who undergo peripheral ultrafiltration. Using individual level patient data, we explored whether it is possible to measure changes in RBV after a single intravenous dose of loop diuretic through the measurement of serial hematocrit values. Based on normally occurring variation in volume-stable patients, the smallest change in RBV that would be detectable by routine serial hematocrits ranges from 6.4% to 8.6%. Methods and Results: Electronic databases were queried for articles that contained predefined MeSH terms in order to identify all studies in which patients received intravenous diuretics. The 764 studies that met our entry criteria were systematically reviewed and manually screened. We then conducted a meta-analysis from 14 studies that provided individual, patient-level data from at least 2 time points: just before and within 3 hours of administration of an intravenous loop diuretic. We found that among a total of 240 patients, RBV decreased by 11% (95% CI 10 to 12%) at 2 hours after an intravenous loop diuretic was given (Figure); there was no significant difference in this finding based on whether or not patients had heart failure. Conclusion: We found that anticipated RBV change with single doses of intravenous loop diuretics exceeds the smallest detectable change in RBV that can be obtained by serial hematocrits. This implies that routine hematocrits can be used to track RBV change across serial doses of intravenous loop diuretics, potentially providing a target for a dry interstitium in acute heart failure.


2005 ◽  
Vol 9 (4) ◽  
pp. 383-392 ◽  
Author(s):  
Casper F M Franssen ◽  
Judith J Dasselaar ◽  
Paulina Sytsma ◽  
Johannes G M Burgerhof ◽  
Paul E Jong ◽  
...  

1981 ◽  
Vol 61 (s7) ◽  
pp. 187s-190s ◽  
Author(s):  
R. S. Smith ◽  
J. L. Reid ◽  
D. J. Warren

1. Blood volume, total exchangeable sodium and the effects of head-up tilt on plasma noradrenaline were studied in 10 normotensive and 11 hypertensive renal transplant recipients. The blood pressure and heart rate responses to infused noradrenaline and isoprenaline were measured. 2. Blood volume and total exchangeable sodium were significantly greater in hypertensive than in normotensive patients. 3. Resting plasma noradrenaline was significantly higher in both groups of transplantees than in normal subjects, but was similar in normotensive and hypertensive patients. 4. Plasma noradrenaline rose in normotensive but not hypertensive patients in response to head-up tilt. 5. The rise in blood pressure in response to infused noradrenaline was significantly greater in hypertensive than in normotensive transplantees. Both groups of patients showed similar responses to infused isoprenaline. 6. Extracellular fluid volume expansion associated with increased α-receptor sensitivity to noradrenaline may contribute to hypertension in renal transplant recipients.


1976 ◽  
Vol 50 (3) ◽  
pp. 207-212 ◽  
Author(s):  
M. E. Safar ◽  
N. PH. Chau ◽  
Y. A. Weiss ◽  
G. M. London ◽  
A. CH. Simon ◽  
...  

1. Blood pressure, blood volume and renal blood flow were determined in 101 men; forty-three were normal subjects and fifty-eight were untreated permanent essential hypertensive patients with normal renal function and equilibrated sodium balance. 2. A significant negative pressure—volume relationship was observed overall. The relationship could be expressed as a hyperbola whose slope expressed the reduction in blood volume per unit rise in pressure: the higher the blood pressure, the lower the slope. Thus essential hypertensive subjects have a smaller decrement in blood volume per unit rise in pressure than normal subjects. 3. The relation between change in blood volume and change in pressure was confirmed in each individual by defining for each a ratio ΔV/ΔP, statistically identical with the hyperbolic slope dV/dP. The ΔV/ΔP ratio was found to be well correlated with the renal blood flow and the creatinine clearance. No correlation existed between the total blood volume and these two renal parameters. 4. It is concluded that the present study demonstrates a blood volume regulation disturbance in essential hypertension and provides evidence from human studies that a renal defect accompanies high blood pressure.


2019 ◽  
Vol 10 (01) ◽  
pp. 33-44
Author(s):  
N.L.G. Sudaryati ◽  
I P. Sudiartawan ◽  
Dwi Mertha Adnyana

The aim of the study was to determine the effectiveness of giving hydrotherapi foot soak in hypertensive patients. The study was conducted with one group pretestposttest design without a control group by measuring blood pressure (pretest) before being given an intervention in the form of foot soak hydrotherm against 15 people with hypertension in Banjar Sri Mandala, Dauhwaru Village, Jembrana Subregency. Then do the blood pressure measurement again (posttest) after finishing the intervention. After the study was completed, the results showed that before the hydrotherapi foot bath intervention, there were 0% of patients classified as normal, 13.32% in prehypertension category, 60.08% in hypertension category I and 26.60% in hypertension category II. After the intervention was given, there were 13.32% of the patients classified as normal, 66.68% in the prehypertension category, 20.00% in the first category of hypertension and no patients belonging to the second grade hypertension category. There is a decrease of 20-30 mmHg for systolic blood pressure and 0-10 mmHg for diastolic blood pressure after intervention. Based on the results of the study it can be concluded that the hydrotherapi foot bath is effectively used to reduce blood pressure in hypertensive patients in the Banjar Sri Mandala, Dauhwaru Village, Jembrana District.


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