Theta burst stimulation versus high-frequency repetitive transcranial magnetic stimulation for poststroke dysphagia

Abstract Background Repetitive transcranial magnetic stimulation (rTMS) has been reported to treat muscle spasticity in post-stroke patients. The purpose of this study was to explore whether combined low-frequency rTMS (LF-rTMS) and cerebellar continuous theta burst stimulation (cTBS) could provide better relief than different modalities alone for muscle spasticity and limb dyskinesia in stroke patients. Methods This study recruited ninety stroke patients with hemiplegia, who were divided into LF-rTMS+cTBS group (n=30), LF-rTMS group (n=30) and cTBS group (three pulse bursts at 50 Hz, n=30). The LF-rTMS group received 1 Hz rTMS stimulation of the motor cortical (M1) region on the unaffected side of the brain, the cTBS group received cTBS stimulation to the cerebellar region, and the LF-rTMS+cTBS group received 2 stimuli as described above. Each group received 4 weeks of stimulation followed by rehabilitation. Muscle spasticity, motor function of limb and activity of daily living (ADL) were evaluated by modified Ashworth Scale (MAS), Fugl-Meyer Assessment (FMA) and Modified Barthel Index (MBI) scores, respectively. Results The MAS score was markedly decreased, FMA and MBI scores were markedly increased in the three groups after therapy than before therapy. In addition, after therapy, LF-rTMS+cTBS group showed lower MAS score, higher FMA and MBI scores than the LF-rTMS group and cTBS group. Conclusion Muscle spasticity and limb dyskinesia of the three groups are all significantly improved after therapy. Combined LF-rTMS and cTBS treatment is more effective in improving muscle spasticity and limb dyskinesia of patients after stroke than LF-rTMS and cTBS treatment alone.

Download Full-text

Cost Analysis of Intermittent Theta Burst Stimulation (iTBS) Versus 10Hz Repetitive Transcranial Magnetic Stimulation (rTMS) in Patients with Treatment Resistant Depression

SSRN Electronic Journal ◽

10.2139/ssrn.3314455 ◽

2019 ◽

Author(s):

Andrew B. Mendlowitz ◽

Alaa Shanbour ◽

Jonathan Downar ◽

Fidel Vila-Rodriguez ◽

Zafiris J. Daskalakis ◽

...

Keyword(s):

Transcranial Magnetic Stimulation ◽

Cost Analysis ◽

Magnetic Stimulation ◽

Repetitive Transcranial Magnetic Stimulation ◽

Treatment Resistant Depression ◽

Theta Burst Stimulation ◽

Treatment Resistant ◽

Burst Stimulation ◽

Resistant Depression ◽

Theta Burst

Download Full-text

Comparison of the Effect of Low-Frequency Repetitive Transcranial Magnetic Stimulation with That of Theta Burst Stimulation on Upper Limb Motor Function in Poststroke Patients

BioMed Research International ◽

10.1155/2017/4269435 ◽

2017 ◽

Vol 2017 ◽

pp. 1-7 ◽

Cited By ~ 4

Author(s):

Takahiro Kondo ◽

Naoki Yamada ◽

Ryo Momosaki ◽

Masato Shimizu ◽

Masahiro Abo

Keyword(s):

Transcranial Magnetic Stimulation ◽

Motor Function ◽

Upper Limb ◽

Magnetic Stimulation ◽

Repetitive Transcranial Magnetic Stimulation ◽

Low Frequency ◽

Theta Burst Stimulation ◽

Burst Stimulation ◽

Performance Time ◽

Theta Burst

Background. The purpose of this study was to evaluate the difference between the therapeutic effect of low-frequency repetitive transcranial magnetic stimulation (LF-rTMS) and that of continuous theta burst stimulation (cTBS), when each is combined with intensive occupational therapy (OT), in poststroke patients with upper limb hemiparesis. Materials and Methods. The study subjects were 103 poststroke patients with upper limb hemiparesis, who were divided into two groups: the LF-rTMS group (n=71) and the cTBS group (three pulse bursts at 50 Hz) (n=32). Each subject received 12 sessions of repetitive transcranial magnetic stimulation of 2,400 pulses applied to the nonlesional hemisphere and 240-min intensive OT (two 60-min one-to-one training sessions and two 60-min self-training exercises) daily for 15 days. Motor function was evaluated using the Fugl-Meyer Assessment (FMA) and the performance time of the Wolf motor function test (WMFT) was determined on the days of admission and discharge. Results. Both groups showed a significant increase in the FMA score and a short log performance time of the WMFT (p<0.001), but the increase in the FMA score was higher in the LF-rTMS group than the cTBS group (p<0.05). Conclusion. We recommend the use of 2400 pulses of LF-rTMS/OT for 2 weeks as treatment for hemiparetic patients.

Download Full-text