Diagnostic accuracy of hepatic venous pressure gradient measurement in the prediction of stage 1 compensated liver cirrhosis in patients with chronic hepatitis B

2013 ◽  
pp. 1 ◽  
Author(s):  
Ki Tae Suk ◽  
Heung Cheol Kim ◽  
Sook Namkung ◽  
Sang Hak Han ◽  
Kyung Chan Choi ◽  
...  
Keyword(s):  
Liver Cirrhosis ◽  
Chronic Hepatitis ◽  
Hepatitis B ◽  
Diagnostic Accuracy ◽  
Pressure Gradient ◽  
Chronic Hepatitis B ◽  
Venous Pressure ◽  
Hepatic Venous Pressure Gradient ◽  
Stage 1 ◽  
Gradient Measurement

scholarly journals Hepatic venous pressure gradient measurement in patients with liver cirrhosis: A correlation with disease severity and variceal bleeding

Medicina ◽  
2009 ◽  
Vol 45 (1) ◽  
pp. 8 ◽  
Author(s):  
Vilma Šilkauskaitė ◽  
Andrius Pranculis ◽  
Dalia Mitraitė ◽  
Laimas Jonaitis ◽  
Vitalija Petrenkienė ◽  
...  
Keyword(s):  
Liver Cirrhosis ◽  
Liver Disease ◽  
Pressure Gradient ◽  
Esophageal Varices ◽  
Variceal Bleeding ◽  
Venous Pressure ◽  
Hepatic Venous Pressure Gradient ◽  
Grade Ii ◽  
The Mean ◽  
Gradient Measurement

The aim of present study was to evaluate relationships between degree of portal hypertension, severity of the disease, and bleeding status in patients with liver cirrhosis. Patients and methods. All study patients with liver cirrhosis underwent hepatic venous pressure gradient measurements, endoscopy, clinical and biochemical evaluation. Liver function was evaluated according to Child-Turcotte-Pugh (Child’s) scoring system. Patients with decompensated cirrhosis (presence of severe ascites, acute variceal bleeding occurring within 14 days, hepatorenal syndrome, cardiopulmonary disorders, transaminase levels >10 times higher the upper normal limit), active alcohol intake, use of antiviral therapy and/or beta-blockers were excluded from the study. Results. One hundred twenty-eight patients with liver cirrhosis (male/female, 67/61; mean age, 53.8±12.7 years) were included into the study. Etiology of cirrhosis was viral hepatitis, alcoholic liver disease, cryptogenic and miscellaneous reasons in 57, 49, 14, and 8 patients, respectively. Child’s stages A, B, and C of liver cirrhosis were established in 28 (21.9%), 70 (54.9%), and 30 (23.4%) patients, respectively. The mean hepatic venous pressure gradient significantly differed among patients with different Child’s classes: 13.8±5.3 mm Hg, 17.3±4.6 mm Hg, and 17.7±5.05 mm Hg in Child’s A, B, and C classes, respectively (P=0.003). The mean hepatic venous pressure gradient in patients with grade I, II, and III varices was 14.8±4.5, 16.1±4.3, and 19.3±4.7 mm Hg, respectively (P=0.0001). Since nonbleeders had both small and large esophageal varices, patients with large varices were analyzed separately. The mean hepatic venous pressure gradient in patients with large (grade II and III) varices was significantly higher than that in patients with small (grade I) varices (17.8±4.8 mm Hg vs 14.6±4.8 mm Hg, P=0.007). Thirty-four (26.6%) patients had a history of previous variceal bleeding; all of them had large (20.6% – grade II, and 79.4% – grade III) varices. In patients with large varices, the mean hepatic venous pressure gradient was significantly higher in bleeders than in nonbleeders (18.7±4.7 mm Hg vs 15.9±4.7 mm Hg, P=0.006). Conclusions. Hepatic venous pressure gradient correlates with severity of liver disease, size of varices, and bleeding status. Among cirrhotics with large esophageal varices, bleeders have a significantly higher hepatic venous pressure gradient than nonbleeders. Hepatic venous pressure gradient measurement is useful in clinical practice selecting cirrhotic patients at the highest risk of variceal bleeding and guiding to specific therapy.

Transjugular liver biopsy and hepatic venous pressure gradient measurement in patients with and without liver cirrhosis

2020 ◽  
Vol Publish Ahead of Print ◽  
Author(s):  
Julia C. Eichholz ◽  
Martha M. Kirstein ◽  
Thorsten Book ◽  
Heiner Wedemeyer ◽  
Torsten Voigtländer
Keyword(s):  
Liver Cirrhosis ◽  
Liver Biopsy ◽  
Pressure Gradient ◽  
Venous Pressure ◽  
Hepatic Venous Pressure Gradient ◽  
Transjugular Liver Biopsy ◽  
Gradient Measurement

scholarly journals Depression in patients with chronic hepatitis B and cirrhosis is closely associated with the severity of liver cirrhosis

2016 ◽  
Vol 12 (1) ◽  
pp. 405-409 ◽  
Author(s):  
HAI-PENG ZHU ◽  
YU-RONG GU ◽  
GENG-LIN ZHANG ◽  
YU-JIE SU ◽  
KE WANG ◽  
...  
Keyword(s):  
Liver Cirrhosis ◽  
Chronic Hepatitis ◽  
Hepatitis B ◽  
Chronic Hepatitis B

Entecavir treatment reduces hepatic events and deaths in chronic hepatitis B patients With liver cirrhosis

Hepatology ◽  
2013 ◽  
Vol 58 (5) ◽  
pp. 1537-1547 ◽  
Author(s):  
Grace Lai-Hung Wong ◽  
Henry Lik-Yuen Chan ◽  
Christy Wing-Hin Mak ◽  
Stanley King-Yeung Lee ◽  
Zoe Man-Yi Ip ◽  
...  
Keyword(s):  
Liver Cirrhosis ◽  
Chronic Hepatitis ◽  
Hepatitis B ◽  
Chronic Hepatitis B
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