A Model for Early Endoscopic Detection of High-Risk Gastroesophageal Varices in Children With Biliary Atresia

2021 ◽  
Vol Publish Ahead of Print ◽  
Author(s):  
Oanez Ackermann ◽  
Paul de Boissieu ◽  
Olivier Bernard ◽  
Emmanuel Gonzalès ◽  
Emmanuel Jacquemin ◽  
...  
2015 ◽  
Vol 60 (5) ◽  
pp. 664-668 ◽  
Author(s):  
Mathieu Duché ◽  
Béatrice Ducot ◽  
Oanez Ackermann ◽  
Emmanuel Jacquemin ◽  
Olivier Bernard

2013 ◽  
Vol 145 (4) ◽  
pp. 801-807 ◽  
Author(s):  
Mathieu Duché ◽  
Béatrice Ducot ◽  
Oanez Ackermann ◽  
Catherine Baujard ◽  
Laurent Chevret ◽  
...  

2013 ◽  
Vol 2013 ◽  
pp. 1-6 ◽  
Author(s):  
Dong Hyun Kim ◽  
Jun Yong Park

Variceal hemorrhage is a common and devastating complication of portal hypertension and is a leading cause of death in patients with cirrhosis. The management of gastroesophageal varices has evolved over the last decade resulting in improved mortality and morbidity rates. Regarding the primary prevention of variceal hemorrhaging, nonselectiveβ-blockers should be the first-line therapy in all patients with medium to large varices and in patients with small varices associated with high-risk features such as red wale marks and/or advanced cirrhosis. EVL should be offered in cases of intolerance or side effects toβ-blockers, or for patients at high-risk for variceal bleeding who have medium or large varices with red wale marks or advanced liver cirrhosis. In acute bleeding, vasoactive agents should be initiated along with antibiotics followed by EVL or endoscopic sclerotherapy (if EVL is technically difficult) within the first 12 hours of presentation. Where available, terlipressin is the preferred agent because of its safety profile and it represents the only drug with a proven efficacy in improving survival. All patients surviving an episode of bleeding should undergo further prophylaxis to prevent rebleeding with EVL and nonselectiveβ-blockers.


2019 ◽  
Vol 49 (10) ◽  
pp. 1162-1168 ◽  
Author(s):  
Shinya Yokoyama ◽  
Masatoshi Ishigami ◽  
Takashi Honda ◽  
Teiji Kuzuya ◽  
Yoji Ishizu ◽  
...  

1998 ◽  
Vol 33 (11) ◽  
pp. 1628-1632 ◽  
Author(s):  
Takashi Sasaki ◽  
Toshimichi Hasegawa ◽  
Kiyokazu Nakajima ◽  
Hirofumi Tanano ◽  
Masafumi Wasa ◽  
...  

2010 ◽  
Vol 2010 ◽  
pp. 1-5 ◽  
Author(s):  
Kohei Fukumoto ◽  
Hideyuki Konishi ◽  
Koichi Soga ◽  
Ki-ichiro Miyawaki ◽  
Hitoshi Okano ◽  
...  

A 68-year-old man with hemophilia A and liver cirrhosis caused by hepatitis C virus was referred to our hospital to receive prophylactic endoscopic treatment for gastroesophageal varices (GOV). He had large, tense, and winding esophageal varices (EV) with cherry red spots extending down to lesser curve, predicting the likelihood of bleeding. Esophageal endoscopic injection sclerotherapy (EIS) was performed with a total 15 mL of 5% ethanolamine oleate with iopamidol (EOI). Radiographic imaging during EIS demonstrated that 5% EOI reached the afferent vein of the varices. He was administered sufficient factor VIII concentrate before and after EIS to prevent massive bleeding from the varices. Seven days after EIS, upper gastrointestinal endoscopy (UGIE) showed that the varices were eradicated almost completely. Eighteen months after EIS, the varices continued to diminish. We report a successful case of safe and effective EIS for GOV in a high-risk cirrhotic patient with hemophilia A.


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