Since Internet is the primary driving force of E-Commerce (EC), it has global phenomena. Consequently, Internet market is diffusing from the west to the east. Nevertheless, cultural, political, economical, technological, social, and overall attitudinal diversity create irresistible barriers for free movement of EC. In this aspect, quality standardization for EC is utmost important. Because quality experts believe that only quality improvement and standardization can provide EC acceptance by global consumers. Expansion of EC from developed countries to developing countries creates an opportunity to redefine the paradigms of quality management practice (QMP) appropriate for global diffusion of EC. This chapter illustrates some related concepts of quality, quality improvement, and different aspects of quality for EC to shed light on QMP.