Ultrasound-Guided Perisutural Botulinum Toxin Injection for Chronic Migraine Headache

2019 ◽  
Vol 98 (8) ◽  
pp. e98-e100 ◽  
Author(s):  
Murat Kara ◽  
Merve Sekizkardeş ◽  
Eda Gürçay ◽  
Ayşen Akinci ◽  
Levent Özçakar
2018 ◽  
Vol 138 (1) ◽  
pp. 99-99 ◽  
Author(s):  
M. Kara ◽  
B. Kaymak ◽  
M. Sekizkardeş ◽  
L. Özçakar

2021 ◽  
pp. 1-11
Author(s):  
Shuo Luan ◽  
Shao-Ling Wu ◽  
Ling-Jun Xiao ◽  
Hai-Yun Yang ◽  
Mei-Xin Liao ◽  
...  

BACKGROUND: Cricopharyngeal muscle dysfunction (CPD) management has been challenging in clinical practice. OBJECTIVE: To compare the efficacy and safety of ultrasound-guided botulinum toxin injection and balloon catheter dilatation in treating CPD. METHODS: Forty patients with CPD were randomly divided into two groups, namely the botulinum toxin injection group (BTX group) and balloon dilatation group (BD group). Patients in the BTX group received a single ultrasound-guided injection of 50 units of botulinum toxin type A, while the BD group received dilatation therapy five times per week, consecutively for two weeks. Relative opening percentage of the upper esophageal sphincter (UES), the penetration-aspiration scale (PAS), and the Dysphagia Outcome Severity Scale (DOSS) were evaluated by a videofluoroscopic swallowing study (VFSS) at baseline, 1-month, and 3-months posttreatment. The Functional Oral Intake Scale (FOIS) and Standardized Swallowing Assessment (SSA) were also used to evaluate participants’ swallowing function at baseline and the 1-week, 2-week, 1-month, and 3-month follow-ups. RESULTS: A generalized estimating equation (GEE) model revealed the significant main effect for time in UES, PAS, DOSS, FOIS, and SSA compared to baseline (P <0.05), while no group-by-time interactions (except for the PAS assessment) or main effect for treatment was detected among the above multiple variances. No systematic complications or severe adverse effects were noted. CONCLUSION: Both ultrasound-guided botulinum toxin type A injections and balloon dilatation therapy have been proven as safe and effective treatments for CPD patients. Future clinical trials with longer follow-up periods and more participants are warranted.


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