Reproducibility of Automated Breast Ultrasonography and Handheld Ultrasonography for Breast Lesion Size Measurement

2022 ◽  
Vol Publish Ahead of Print ◽  
Author(s):  
Ko Woon Park ◽  
Eun Young Ko ◽  
Surin Park ◽  
Boo-Kyung Han ◽  
Eun Sook Ko ◽  
...  
Keyword(s):  
Breast Lesion ◽  
Lesion Size ◽  
Size Measurement ◽  
Breast Ultrasonography

scholarly journals Can Cut-Off-Values for Tumor Size or Patient Age in Breast Ultrasound Reduce Unnecessary Biopsies or is it all About Bi-rads?– A Retrospective Analysis of 763 Biopsied T1-Sized Lesions

2017 ◽  
Vol 03 (03) ◽  
pp. E94-E98 ◽  
Author(s):  
Laura Holzer-Fruehwald ◽  
Matthias Meissnitzer ◽  
Michael Weber ◽  
Stephan Holzer ◽  
Klaus Hergan ◽  
...  
Keyword(s):  
Regression Models ◽  
Breast Lesion ◽  
Binary Logistic Regression ◽  
Lesion Size ◽  
Breast Lesions ◽  
Predictive Values ◽  
Logistic Regression Models ◽  
Independent Variables ◽  
Oval Shape ◽  
Histological Result

Abstract Aims and Objectives To assess whether it is possible to establish a size cut-off-value for sonographically visible breast lesions in a screening situation, under which it is justifiable to obviate a biopsy and to evaluate the grayscale characteristics of the identified lesions. Materials and Methods Images of sonographically visible and biopsied breast lesions of 684 patients were retrospectively reviewed and assessed for the following parameters: size, shape, margin, lesion boundary, vascularity, patient’s age, side of breast, histological result, and initial BI-RADS category. Statistical analyses (t-test for independent variables, ROC analyses, binary logistic regression models, cross-tabulations, positive/negative predictive values) were performed using IBM SPSS (Version 21.0). Results Of all 763 biopsied lesions, 223 (29.2%) showed a malignant histologic result, while 540 (70.8%) were benign. Although we did find a statistically significant correlation of malignancy and lesion size (p=0.031), it was not possible to define a cut-off value, under which it would be justifiable to obviate a biopsy in terms of sensitivity and specificity (AUC: 0.558) at any age. Lesions showing the characteristics of a round or oval shape, a sharp delineation and no echogenic rim (n=112) were benign with an NPV of 99.1%. Conclusion It is not possible to define a cut-off value for size or age, under which a biopsy of a sonographically visible breast lesion can be obviated in the screening situation. The combination of the 3 grayscale characteristics, shape (round or oval), margin (circumscribed) and no echogenic-rim sign, showed an NPV of 99.1%. Therefore, it seems appropriate to classify such lesions as BI-RADS 2.

Comparative analysis of MRI vs mammography in evaluation of size, number of lesions and nodal status of breast cancer

2006 ◽  
Vol 24 (18_suppl) ◽  
pp. 600-600
Author(s):  
S. Saha ◽  
S. Chitneni ◽  
R. Sehgal ◽  
M. Arora ◽  
B. Desouza ◽  
...  
Keyword(s):  
Gold Standard ◽  
Breast Lesion ◽  
Breast Mri ◽  
Lesion Size ◽  
Contralateral Breast ◽  
T2 Lesions ◽  
Size Number ◽  
Stage Classification ◽  
The Mean ◽  
Neo Adjuvant Chemotherapy

600 Background: Breast MRI is thought to be better in evaluating patients (pts) with BrCa. Our study was to compare MRI vs mam to predict leisons and LNS in BrCa. Methods: A retrospective study of 100 consecutive pts with pathologically proven BrCa was done. All had preoperative MRI and mam. Findings were compared to the final pathologic size, used as gold standard. MRI and was done at same center and single surgeon did all surgeries. Results: Of 100 pts,MRI reported 124 lesions. MRI reported size in 107 and mam reported size in 63 lesions. In MRI detected sizes 8% had same size as pathological size, 66% were overestimated by a mean of 0.64cm and 26% were underestimated by a mean of 0.48cm. For mam lesions, 10% had same size, 34% were overestimated by a mean of 1.10cm, 57% were underestimated by a mean of 0.78 cm. Total of 25 additional lesions were found in 23 pts in same and 6 leisons in 6 pts in contralateral breast by MRI. MRI also detected enlarged axillary and intramammary LN in 15% pts, 40% were true positives(+ve) and 60% were false +ve. One pt had metastatic LN in the contralateral axilla detected by MRI and confirmed by lymphoscintogram and pathology. 3% pts had neo-adjuvant chemotherapy Conclusion: In our study mam underestimated the breast lesion size in pts significantly more than MRI, but MRI overestimated BrCa lesion size in more number of pts. The mean difference in size on MRI when compared to the pathological size is less than 1 cm, while mam overestimated by a mean of greater than 1cm. This might be particularly important for T1 and T2 lesions, where size is the most important criterion for the T-stage classification. The identification of additional lesions and enlarged LN on MRI further validates the utility of MRI. [Table: see text] No significant financial relationships to disclose.

Agreement in Breast Lesion Assessment and Final BI-RADS Classification Between Radial and Meander-Like Breast Ultrasound

2020 ◽  
Author(s):  
Pascale Brasier-Lutz ◽  
Claudia Jäggi-Wickes ◽  
Sabine Schaedelin ◽  
Rosemarie Burian ◽  
Cora-Ann Schoenenberger ◽  
...  
Keyword(s):  
Breast Lesion ◽  
Morphological Characteristics ◽  
Lesion Size ◽  
Breast Ultrasound ◽  
Architectural Distortion ◽  
Suitable Alternative ◽  
Lesion Location ◽  
High Degree ◽  
Face Localization

Abstract Background: This study prospectively investigates the agreement between radial (r-US) and meander-like (m-US) breast ultrasound with regard to lesion location, lesion size, morphological characteristics and final BI-RADS classification of individual breast lesions. Methods: Each patient of a consecutive, unselected, mixed collective received a dual ultrasound examination. Results: The agreement between r-US and m-US for lesion location ranged from good (lesion to mammilla distance ICC 0.64; lesion to skin distance ICC 0.72) to substantial (clock-face localization κ 0.70). For lesion size the agreement was good (diameter ICC 0.72; volume ICC 0.69), for lesion margin and architectural distortion it was substantial (κ 0.68 and 0.70, respectively). Most importantly, there was a substantial agreement (κ 0.76) in the final BI-RADS classification between r-US and m-US.Conclusions: Our recent comparison of radial and meander-like breast US revealed that the diagnostic accuracy of the two scanning methods was comparable. In this study, we observe a high degree of agreement between m-US and r-US for the lesion description (location, size, morphology) and final BI-RADS classification. These findings corroborate that r-US is a suitable alternative to m-US in daily clinical practice.Trial registration: NCT02358837. Registered January 2015, retrospectively registeredhttps://clinicaltrials.gov/ct2/results?cond=&term=NCT02358837&cntry=&state=&city=&dist=

Influence of Breast Lesion Size and Histologic Findings on Tumor Detection Rate of a Computer-aided Detection System

Radiology ◽  
2003 ◽  
Vol 228 (3) ◽  
pp. 851-856 ◽  
Author(s):  
Ansgar Malich ◽  
Dieter Sauner ◽  
Christiane Marx ◽  
Mirjam Facius ◽  
Thomas Boehm ◽  
...  
Keyword(s):  
Detection Rate ◽  
Breast Lesion ◽  
Detection System ◽  
Tumor Detection ◽  
Lesion Size ◽  
Computer Aided Detection ◽  
Computer Aided ◽  
Tumor Detection Rate

scholarly journals GFAP and S100B Protein are Associated with Discharged NIHSS of Anterior Circulation Ischemic Stroke

2012 ◽  
Vol 4 (2) ◽  
pp. 112
Author(s):  
Yenny Surjawan ◽  
Suryani As'ad ◽  
Teguh A S Ranakusuma ◽  
Andi Wijaya
Keyword(s):  
Ischemic Stroke ◽  
Neurological Deficit ◽  
Lesion Size ◽  
Brain Cell ◽  
S100b Protein ◽  
Size Measurement ◽  
Anterior Circulation ◽  
Ischemic Lesion ◽  
Stroke Diagnosis ◽  
Additional Approach

BACKGROUND: Patient with larger ischemic lesion will suffer more severe neurogical deficit. The utility of MRI for lesion size measurement is still limited, therefore additional approach was pursued through examination of markers released by damaged brain cell, GFAP and S100B protein. The aim of this study is to know whether both markers are associated with the neurological deficit of anterior circulation ischemic stroke. METHODS: This observational prospective study enrolled 74 patients with anterior circulation ischemic stroke diagnosis. GFAP and S100B protein were measured with ELISA using blood collected at 48 to 72 hours after onset. The neurological deficit was assessed with NIHSS ad discharged.RESULTS: There was a significant association between GFAP level and discharged NIHSS (p=0.008) with 100% sensitivity and 100% negative predictive value. S100B protein also showed a significant correlation with discharged NIHSS (r=0.488; p=0.000) and this correlation could be described with an equation (OR=1.009; 95% CI=1.0003-1.0188; p=0.044). S100B protein at 78.3215 ng/L would give true prediction as 73.9% (95% CI=62.7%-85.2%, p=0.001). CONCLUSIONS: GFAP and S100B protein that were measured at 48 to 72 hours after onset were significantly associated with NIHSS at discharge. KEYWORDS: GFAP, S100B protein, discharged NIHSS, ischemic stroke

scholarly journals Breast lesion size assessment in mastectomy specimens

Medicine ◽  
2019 ◽  
Vol 98 (37) ◽  
pp. e17082 ◽  
Author(s):  
Susanne Wienbeck ◽  
Johannes Uhlig ◽  
Uwe Fischer ◽  
Martin Hellriegel ◽  
Eva von Fintel ◽  
...  
Keyword(s):  
Breast Lesion ◽  
Lesion Size

scholarly journals Agreement in breast lesion assessment and final BI-RADS classification between radial and meander-like breast ultrasound

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Pascale Brasier-Lutz ◽  
Claudia Jäggi-Wickes ◽  
Sabine Schaedelin ◽  
Rosemarie Burian ◽  
Cora-Ann Schoenenberger ◽  
...  
Keyword(s):  
Breast Lesion ◽  
Morphological Characteristics ◽  
Lesion Size ◽  
Breast Ultrasound ◽  
Architectural Distortion ◽  
Suitable Alternative ◽  
Lesion Location ◽  
High Degree ◽  
Face Localization

Abstract Background This study prospectively investigates the agreement between radial (r-US) and meander-like (m-US) breast ultrasound with regard to lesion location, lesion size, morphological characteristics and final BI-RADS classification of individual breast lesions. Methods Each patient of a consecutive, unselected, mixed collective received a dual ultrasound examination. Results The agreement between r-US and m-US for lesion location ranged from good (lesion to mammilla distance ICC 0.64; lesion to skin distance ICC 0.72) to substantial (clock-face localization κ 0.70). For lesion size the agreement was good (diameter ICC 0.72; volume ICC 0.69), for lesion margin and architectural distortion it was substantial (κ 0.68 and 0.70, respectively). Most importantly, there was a substantial agreement (κ 0.76) in the final BI-RADS classification between r-US and m-US. Conclusions Our recent comparison of radial and meander-like breast US revealed that the diagnostic accuracy of the two scanning methods was comparable. In this study, we observe a high degree of agreement between m-US and r-US for the lesion description (location, size, morphology) and final BI-RADS classification. These findings corroborate that r-US is a suitable alternative to m-US in daily clinical practice. Trial registration NCT02358837. Registered January 2015, retrospectively registered https://clinicaltrials.gov/ct2/results?cond=&term=NCT02358837&cntry=&state=&city=&dist=

Lesion size measurement in femoral head necrosis

2018 ◽  
Vol 42 (7) ◽  
pp. 1585-1591 ◽  
Author(s):  
Marvin E. Steinberg ◽  
Seong C. Oh ◽  
Viviane Khoury ◽  
Jayaram K. Udupa ◽  
David R. Steinberg
Keyword(s):  
Femoral Head ◽  
Lesion Size ◽  
Femoral Head Necrosis ◽  
Size Measurement

scholarly journals Minimally invasive breast cancer excision using the breast lesion excision system under ultrasound guidance

2020 ◽  
Vol 184 (1) ◽  
pp. 37-43
Author(s):  
W. B. G. Sanderink ◽  
L. J. A. Strobbe ◽  
P. Bult ◽  
M. S. Schlooz-Vries ◽  
S. Lardenoije ◽  
...  
Keyword(s):  
Breast Lesion ◽  
Lobular Carcinoma ◽  
Breast Mri ◽  
Lesion Size ◽  
Breast Cancers ◽  
Breast Carcinomas ◽  
Small Breast ◽  
Technical Complication ◽  
Invasive Breast Carcinomas ◽  
Invasive Carcinomas

Abstract Purpose To assess the feasibility of completely excising small breast cancers using the automated, image-guided, single-pass radiofrequency-based breast lesion excision system (BLES) under ultrasound (US) guidance. Methods From February 2018 to July 2019, 22 patients diagnosed with invasive carcinomas ≤ 15 mm at US and mammography were enrolled in this prospective, multi-center, ethics board-approved study. Patients underwent breast MRI to verify lesion size. BLES-based excision and surgery were performed during the same procedure. Histopathology findings from the BLES procedure and surgery were compared, and total excision findings were assessed. Results Of the 22 patients, ten were excluded due to the lesion being > 15 mm and/or being multifocal at MRI, and one due to scheduling issues. The remaining 11 patients underwent BLES excision. Mean diameter of excised lesions at MRI was 11.8 mm (range 8.0–13.9 mm). BLES revealed ten (90.9%) invasive carcinomas of no special type, and one (9.1%) invasive lobular carcinoma. Histopathological results were identical for the needle biopsy, BLES, and surgical specimens for all lesions. None of the BLES excisions were adequate. Margins were usually compromised on both sides of the specimen, indicating that the excised volume was too small. Margin assessment was good for all BLES specimens. One technical complication occurred (retrieval of an empty BLES basket, specimen retrieved during subsequent surgery). Conclusions BLES allows accurate diagnosis of small invasive breast carcinomas. However, BLES cannot be considered as a therapeutic device for small invasive breast carcinomas due to not achieving adequate excision.

Sign in / Sign up

Export Citation Format

Share Document