Epithelial-Myoepithelial Carcinoma in Minor Salivary Gland of the Hard Palate

2008 ◽  
Vol 19 (6) ◽  
pp. 1689-1691 ◽  
Author(s):  
Heikki Teppo ◽  
Ilkka Paronen
Author(s):  
Basudev Mahato ◽  
Samir Mandal ◽  
Tushar Deb ◽  
Jay Gopal Ray ◽  
Keya Chaudhuri

2021 ◽  
pp. 014556132110666
Author(s):  
Huan Li ◽  
Yi-Lin Long ◽  
Shi-Fei Wang ◽  
Ling-Lin Su

Epithelial–myoepithelial carcinoma (EMC) is a rare tumor that occurs mainly in the major salivary glands. Cases occurring in the nasal cavity are rarely reported. The patient was a 48-year-old woman with a postoperative pathological diagnosis of EMC. The patient recovered well after surgery. We consulted and summarized all previous cases of nasal EMC. We also discuss the clinical presentation, treatment, and prognosis of EMC of the nasal cavity and paranasal sinuses.


1996 ◽  
Vol 89 (9) ◽  
pp. 1113-1118
Author(s):  
Yoko NOBUTO ◽  
Nobuaki AYADA ◽  
Takashi KAWAKAMI ◽  
Mamoru MIYAGUCHI ◽  
Kazunori NISHIZAKI

2015 ◽  
Vol 32 (2) ◽  
pp. 130-135
Author(s):  
Tsukasa Tsuji ◽  
Hideaki Kitada ◽  
Sinnosuke Abe ◽  
Hitoshi Ikeda ◽  
Eiji Nakayama

2021 ◽  
Author(s):  
Kohei Okuyama ◽  
Yasuyuki Michi ◽  
Yoshihisa Kashima ◽  
Hirofumi Tomioka ◽  
Hideaki Hiral ◽  
...  

Abstract Epithelial-myoepithelial carcinoma (EMC) is a rare malignant salivary gland tumor, which is especially uncommon in the minor salivary glands (MSG). We report literature review of EMC of the MSGs with our experience of two cases. Case 1 is a 75-year-old woman with a hard elastic mass in the hard palate, sized 2.5 × 2 cm without ulceration. Incisional biopsy was suggestive of pleomorphic adenoma. Tumor resection was performed with adequate surgical margin. Case 2 is a 44-year-old woman with a mass in the hard palate, sized 1.8 × 1.6 cm without ulceration. Incisional biopsy was suggestive of pleomorphic adenoma or a low-grade salivary gland carcinoma and intraoral tumor resection was performed. Both have good postoperative courses and are alive with no evidence of local recurrence or metastasis at 25 and 10 months. The Ki-67 labeling index in Case 1 and 2 were 10.6 and 3.8 %. Considering that the anatomy, structure, and size of salivary glands are quite different from MSGs, EMCs of the MSG cannot be predicted similarly to EMCs of the major salivary glands. The present review with 18 cases revealed no consensus on treatment methods for MSG cases other than surgery.


Medicine ◽  
2020 ◽  
Vol 99 (5) ◽  
pp. e19072
Author(s):  
Young Sub Lee ◽  
Sun Mok Ha ◽  
Seung Won Paik ◽  
Hui Joon Yang ◽  
Hyun Jong Jeon ◽  
...  

2016 ◽  
Vol 6 (1) ◽  
pp. 1-7
Author(s):  
Suma Kaza ◽  
T Jaya Mastan Rao ◽  
Anupama Mikkilineni ◽  
G Venkata Ratnam ◽  
D Ranga Rao

Abstract Assessment of proliferation is a means of predicting local recurrence and metastatic potential of malignancies. A mitotic count is not an ideal marker for proliferation in certain situations, such as salivary gland neoplasms. Ki-67 expression as a proliferation marker has been investigated in many human tumors. In the present study, Mitotic index (MI) and Ki-67 index were studied in pleomorphic adenoma, basal cell adenoma, mucoepidermoid carcinoma, adenoid cystic carcinoma epithelial myoepithelial carcinoma, carcinoma ex Pleomorphic adenoma and adenocarcinoma of salivary glands. The results were compared. The MI was similar in benign neoplasms, mucoepidermoid carcinoma and epithelial myoepithelial carcinoma, whereas it was high in carcinoma ex pleomorphic adenoma, adenocarcinoma and adenoid cystic carcinoma. The Ki-67 index was different in basal cell adenoma and pleomorphic adenoma. It was helpful in differentiating high grade and low grade mucoepidermoid carcinoma. It highlighted the malignant behavior of epithelial myoepithelial carcinoma. It was concluded that Ki-67 in benign neoplasms is 5% or less and in malignant ones more than 23% with a few exceptions. In mucoepidermoid carcinoma and epithelial myoepithelial carcinoma, Ki-67 index was found to be a better indicator for aggressiveness. These findings will be presented in this paper, with review of literature. How to cite this article Kaza S, Rao TJM, Mikkilineni A, Ratnam GV, Rao DR. Ki-67 Index in Salivary Gland Neoplasms. Int J Phonosurg Laryngol 2016;6(1):1-7.


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