Long-Term Clinical and Biochemical Follow-up in Medullary Thyroid Carcinoma

2007 ◽  
Vol 246 (5) ◽  
pp. 815-821 ◽  
Author(s):  
Kenko Cupisti ◽  
Achim Wolf ◽  
Andreas Raffel ◽  
Matthias Schott ◽  
Daniel Miersch ◽  
...  
Keyword(s):  
Thyroid Carcinoma ◽  
Medullary Thyroid Carcinoma ◽  
Medullary Thyroid

Medullary Thyroid Carcinoma: Clinical Features and Long-Term Follow-up of Seventy-Eight Patients Treated Between 1969 and 1986

Thyroid ◽  
1998 ◽  
Vol 8 (6) ◽  
pp. 517-523 ◽  
Author(s):  
M.E. GIRELLI ◽  
D. NACAMULLI ◽  
M.R. PELIZZO ◽  
D. DE VIDO ◽  
C. MIAN ◽  
...  
Keyword(s):  
Thyroid Carcinoma ◽  
Medullary Thyroid Carcinoma ◽  
Clinical Features ◽  
Medullary Thyroid ◽  
Long Term Follow Up

scholarly journals Clinico-pathologic and dynamic prognostic factors in sporadic and familial medullary thyroid carcinoma: an Israeli multi-center study

2019 ◽  
Vol 181 (1) ◽  
pp. 13-21 ◽  
Author(s):  
Orit Twito ◽  
Simona Grozinsky-Glasberg ◽  
Sigal Levy ◽  
Gideon Bachar ◽  
David J Gross ◽  
...  
Keyword(s):  
Thyroid Carcinoma ◽  
Medullary Thyroid Carcinoma ◽  
Initial Treatment ◽  
Treatment Decision ◽  
Distant Metastases ◽  
Medullary Thyroid ◽  
Measure Of Association ◽  
Disease Persistence

ObjectiveMultiple clinical, pathological and biochemical variables, including the response to initial treatment, are associated with medullary thyroid carcinoma (MTC) prognosis. Studies that include separate analyses of familial and sporadic MTC patients followed for long period are scarce. This study evaluated the association between baseline clinico-pathologic variables and response to initial treatment and short- and long-term disease outcomes in sporadic and familial MTC.MethodsPatients treated for MTC at four tertiary medical centers were retrospectively analyzed. Clinical and pathological data were collected. The outcomes measured included disease persistence 1 year after diagnosis, disease persistence at last follow-up, disease-related mortality (DRM) and all-cause mortality.ResultsThe study enrolled 193 patients (mean age: 48.9 ± 18.7, 44.7% males), of whom 18.1% were familial cases. The mean follow-up period was 10.1 ± 9.4 years (8.5 ± 8.1 in sporadic and 16.9 ± 11.6 in familial MTC). Disease persistence 1-year after diagnosis and at last follow-up was detected in 56.1 and 60.4% patients, respectively. All-cause and DRM were 28.5 and 12.6%, respectively. Extra-thyroidal extension (ETE) and distant metastases (DM) were associated with disease persistence at last follow-up. ETE and DM were also significantly associated with DRM. Complete remission 1 year after diagnosis had high correlation with no evidence of disease at last follow-up (Cramer’s V measure of association 0.884,P < 0.001) and with 100% disease-specific survival (Cramer’s V measure of association 0.38,P < 0.001).ConclusionsApart from clinico-pathologic parameters, close correlation was found between 1-year status and long-term prognosis. These results underscore the importance of combining classical and dynamic factors for both sporadic and familial MTC prognostication and treatment decision making.

Medullary Thyroid Carcinoma: Clinicopathologic Features and Long-Term Follow-Up of 65 Patients Treated During 1946 Through 1970

1992 ◽  
Vol 67 (10) ◽  
pp. 934-940 ◽  
Author(s):  
HOSSEIN GHARIB ◽  
WILLIAM M. McCONAHEY ◽  
ROBERT D. TIEGS ◽  
ERIK J. BERGSTRALH ◽  
JOHN R. GOELLNER ◽  
...  
Keyword(s):  
Thyroid Carcinoma ◽  
Medullary Thyroid Carcinoma ◽  
Clinicopathologic Features ◽  
Medullary Thyroid ◽  
Long Term Follow Up

Abstract #87: Long-Term Survival in a Patient with MEN2B and Metastatic Medullary Thyroid Carcinoma

2004 ◽  
Vol 10 ◽  
pp. 29-30
Author(s):  
Claudia Panzer ◽  
Robert Beazley ◽  
Stuart Chipkin ◽  
Susanne Ebner
Keyword(s):  
Thyroid Carcinoma ◽  
Medullary Thyroid Carcinoma ◽  
Term Survival ◽  
Long Term Survival ◽  
Medullary Thyroid

Long-term Outcome of Reoperations for Medullary Thyroid Carcinoma

2008 ◽  
Vol 32 (5) ◽  
pp. 754-765 ◽  
Author(s):  
Elizabeth Fialkowski ◽  
Mary DeBenedetti ◽  
Jeffrey Moley
Keyword(s):  
Thyroid Carcinoma ◽  
Medullary Thyroid Carcinoma ◽  
Term Outcome ◽  
Long Term Outcome ◽  
Medullary Thyroid
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