The Sensitivity and the False Negative Rate of Fine Needle Aspiration Biopsy in Thyroid Nodule

2008 ◽  
Vol 248 (2) ◽  
pp. 343-344
Author(s):  
Bekir Kuru
Keyword(s):  
Thyroid Nodule ◽  
Fine Needle Aspiration ◽  
Fine Needle Aspiration Biopsy ◽  
False Negative ◽  
False Negative Rate ◽  
Needle Aspiration ◽  
Aspiration Biopsy ◽  
Fine Needle ◽  
Negative Rate ◽  
Needle Aspiration Biopsy

Diagnosis and Subclassification of Breast Carcinoma by Fine-Needle Aspiration Biopsy

2002 ◽  
Vol 126 (12) ◽  
pp. 1453-1457 ◽  
Author(s):  
Nancy A. Young ◽  
Dina R. Mody ◽  
Diane D. Davey
Keyword(s):  
Breast Carcinoma ◽  
Fine Needle Aspiration ◽  
Fine Needle Aspiration Biopsy ◽  
False Negative ◽  
False Negative Rate ◽  
Needle Aspiration ◽  
Aspiration Biopsy ◽  
Ductal Adenocarcinoma ◽  
Fine Needle ◽  
Needle Aspiration Biopsy

Abstract Context.—The College of American Pathologists Interlaboratory Comparison Program in Non-Gynecologic Cytopathology is a popular educational program for nongynecologic cytology that had 1018 participating laboratories by the end of 2000. Data generated from this program allow for tracking performance on slides in a diverse group of laboratories. Objective.—We reviewed the performance of participating laboratories on fine-needle aspiration biopsies of the breast with particular interest in the ability of participants to accurately subclassify breast carcinoma. Design.—We reviewed the responses of participating laboratories for glass slides of breast fine-needle aspiration biopsies for the year 2000. We analyzed benchmarking data provided for each specific diagnosis. Results.—The overall false-negative rate for laboratories was 6.2%, and the overall false-positive rate was 1.1%. Most of the breast carcinomas were correctly identified as malignant on the general diagnosis, but participants had more difficulty subclassifying types of breast carcinoma. The rate of correct exact diagnosis was 65% for ductal adenocarcinoma, 20% for lobular adenocarcinoma, 12% for medullary carcinoma, and 27% for mucinous carcinoma. Conclusions.—This study shows that fine-needle aspiration biopsy of the breast is a reliable method for the diagnosis of breast carcinoma, but difficulties still exist in our ability to determine tumor subtype.

Diagnostic Value of Fine Needle Aspiration Biopsy in Neoplasms of the Head and Neck

1981 ◽  
Vol 89 (1) ◽  
pp. 62-66 ◽  
Author(s):  
A. Sismanis ◽  
Joseph Merriam ◽  
Kent T. Yamaguchi ◽  
Stanley M. Shapshay ◽  
M. Stuart Strong
Keyword(s):  
Head And Neck ◽  
Fine Needle Aspiration ◽  
Fine Needle Aspiration Biopsy ◽  
Malignant Tumors ◽  
False Negative ◽  
False Negative Rate ◽  
Needle Aspiration ◽  
Aspiration Biopsy ◽  
Fine Needle ◽  
Needle Aspiration Biopsy

In this paper, the cytologic findings of 90 aspirates obtained by the fine needle aspiration technique from head and neck masses are compared with the histology of the permanent section. The overall concurrence rate between cytologic and histologic findings for benign and malignant tumors is 80%. There is a 6.6% false negative rate. There are no false positive results. Fine needle aspiration biopsy is found to be safe, complication free, and most helpful in treatment planning.

Chemical neuritis after fine needle aspiration biopsy of thyroid nodule

2006 ◽  
Vol 29 (10) ◽  
pp. 947-948 ◽  
Author(s):  
U. M. Musharrafieh ◽  
M. P. Nasrallah ◽  
R. A. Sawaya ◽  
Z. M. Hijazi ◽  
M. C. Haddad
Keyword(s):  
Thyroid Nodule ◽  
Fine Needle Aspiration ◽  
Fine Needle Aspiration Biopsy ◽  
Needle Aspiration ◽  
Aspiration Biopsy ◽  
Fine Needle ◽  
Needle Aspiration Biopsy

Pediatric Thyroid Nodules: Disease Demographics and Clinical Management as Determined by Fine Needle Aspiration Biopsy

PEDIATRICS ◽  
1995 ◽  
Vol 95 (1) ◽  
pp. 46-49
Author(s):  
Stephen S. Raab ◽  
Jan F. Silverman ◽  
Tarik M. Elsheikh ◽  
Patricia A. Thomas ◽  
Paul E. Wakely
Keyword(s):  
Fine Needle Aspiration ◽  
Thyroid Nodules ◽  
Fine Needle Aspiration Biopsy ◽  
False Negative ◽  
Needle Aspiration ◽  
Aspiration Biopsy ◽  
Benign Nodule ◽  
Fine Needle ◽  
Minimal Invasiveness ◽  
Needle Aspiration Biopsy

Objective. The prevalence of thyroid nodularity in children has been estimated to be 1.8%. The reported prevalence of specific diseases which comprise these nodules is conflicting as evidenced by a reported range of malignancy of 2 to 50% in solitary nodules. In order to better classify pediatric (<18 years old) thyroid disease and evaluate the utility of fine needle aspiration biopsy (FNAB) in this patient population, we retrospectively reviewed 66 FNABs from 64 thyroid nodules and 2 perithyroid lymph nodes from 57 patients. Methodology. Patients: The study was composed of 8 males and 49 females who ranged in age from 1 to 18 years old (mean = 13.1). Design: Surgical and/or clinical follow-up was obtained in all patients. The 66 FNAB diagnoses were initially classified into specific diseases. However, for the purpose of this review, the cases were classified as: 3 insufficient, 51 benign, 8 suspicious, and 4 malignant. Results. There were no "false positives" and one "false negative" (a papillary carcinoma was misdiagnosed as a benign nodule). Overall, 10 patients (18%) had malignant thyroid lesions, including 8 papillary carcinomas and 2 follicular carcinomas. Benign diagnoses included benign nodule, cyst, lymphocytic thyroiditis, granulomatous thyroiditis, hyperplasia, and abscess. Conclusions. The prevalence of malignancy in pediatric patients with thyroid nodules was 18%. We conclude that, because of its high diagnostic accuracy and minimal invasiveness, FNAB is useful in the management of pediatric thyroid nodules.

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