The pulse pressure/heart rate ratio as a marker of stroke volume changes during hemorrhagic shock and resuscitation in anesthetized swine

2013 ◽  
Vol 74 (6) ◽  
pp. 1438-1445 ◽  
Author(s):  
Julien Pottecher ◽  
Denis Chemla ◽  
Lorenço Xavier ◽  
Ngai Liu ◽  
Thierry Chazot ◽  
...  
Keyword(s):  
Heart Rate ◽  
Stroke Volume ◽  
Hemorrhagic Shock ◽  
Pulse Pressure ◽  
Rate Ratio ◽  
Volume Changes

Prehospital shock index and pulse pressure/heart rate ratio to predict massive transfusion after severe trauma

2016 ◽  
Vol 81 (4) ◽  
pp. 713-722 ◽  
Author(s):  
Julien Pottecher ◽  
François-Xavier Ageron ◽  
Clémence Fauché ◽  
Denis Chemla ◽  
Eric Noll ◽  
...  
Keyword(s):  
Heart Rate ◽  
Pulse Pressure ◽  
Rate Ratio ◽  
Massive Transfusion ◽  
Severe Trauma ◽  
Shock Index

Cardiac scope in amphibians: transition to terrestrial life

1991 ◽  
Vol 69 (7) ◽  
pp. 2010-2013 ◽  
Author(s):  
Stanley S. Hillman
Keyword(s):  
Heart Rate ◽  
Stroke Volume ◽  
Aerobic Capacity ◽  
Important Determinant ◽  
Volume Changes ◽  
Maximal Aerobic Capacity ◽  
Content Difference ◽  
Terrestrial Life ◽  
Systemic Oxygen ◽  
Primary Problem

Systemic oxygen transport essentially limits maximal aerobic capacity in amphibians and consequently may be an important determinant of aerobically supported behaviors. Exercise widens arteriovenous oxygen content difference (5×) and increases heart rate (2×), whereas stroke volume changes very little over resting values. Dehydration is the primary problem facing amphibians in the transition to terrestrial life. Dehydration influences cardiac scope by imposing hyperosmotic, hypovolemic, and hyperviscous stresses on cardiac function. The ability to compensate for hypovolemic stress is the principal adaptation sustaining cardiac scope in more dehydration-tolerant amphibians.

scholarly journals Echocardiographic measure of dynamic arterial elastance predict pressure response during norepinephrine weaning: an observational study

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Maxime Nguyen ◽  
Osama Abou-Arab ◽  
Stéphane Bar ◽  
Hervé Dupont ◽  
Bélaïd Bouhemad ◽  
...  
Keyword(s):  
Stroke Volume ◽  
Pulse Pressure ◽  
Pulse Pressure Variation ◽  
Stroke Volume Variation ◽  
Pressure Variation ◽  
Pressure Response ◽  
Arterial Elastance ◽  
Volume Variation ◽  
Norepinephrine Dose ◽  
Stroke Volume Variations

AbstractThe purpose of this study was to determine whether dynamic elastance EAdyn derived from echocardiographic measurements of stroke volume variations can predict the success of a one-step decrease of norepinephrine dose. In this prospective single-center study, 39 patients with vasoplegic syndrome treated with norepinephrine and for whom the attending physician had decided to decrease norepinephrine dose and monitored by thermodilution were analyzed. EAdyn is the ratio of pulse pressure variation to stroke volume variation and was calculated from echocardiography stroke volume variations and from transpulmonary thermodilution. Pulse pressure variation was obtained from invasive arterial monitoring. Responders were defined by a decrease in mean arterial pressure (MAP) > 10% following norepinephrine decrease. The median decrease in norepinephrine was of 0.04 [0.03–0.05] µg kg−1 min−1. Twelve patients (31%) were classified as pressure responders with a median decrease in MAP of 13% [12–15%]. EAdyn was lower in pressure responders (0.40 [0.24–0.57] vs 0.95 [0.77–1.09], p < 0.01). EAdyn was able to discriminate between pressure responders and non-responders with an area under the curve of 0.86 (CI95% [0.71 to1.0], p < 0.05). The optimal cut-off was 0.8. EAdyn calculated from the echocardiographic estimation of the stroke volume variation and the invasive arterial pulse pressure variation can be used to discriminate pressure response to norepinephrine weaning. Agreement between EAdyn calculated from echocardiography and thermodilution was poor. Echocardiographic EAdyn might be used at bedside to optimize hemodynamic treatment.

scholarly journals Evaluation of Stroke Volume Variation Obtained by the FloTrac™/Vigileo™ System to Guide Preoperative Fluid Therapy in Patients Undergoing Brain Surgery

2012 ◽  
Vol 40 (3) ◽  
pp. 1175-1181 ◽  
Author(s):  
J Li ◽  
Fh Ji ◽  
Jp Yang
Keyword(s):  
Blood Pressure ◽  
Heart Rate ◽  
Stroke Volume ◽  
Stroke Volume Variation ◽  
Brain Surgery ◽  
Fluid Loading ◽  
Volume Loading ◽  
Fluid Infusion ◽  
Volume Variation ◽  
Ringer’S Lactate

OBJECTIVE: The accuracy of stroke volume variation (SVV) obtained by the FloTrac™/Vigileo™ system in otherwise healthy patients undergoing brain surgery was assessed. METHODS: Anaesthesia was induced in 48 patients with minimal fluid infusion. Before surgery, fluid volume loading was performed by infusion with Ringer's lactate solution in 200 ml steps over 3 min, repeated successively if the patient responded with an increase in stroke volume of ≥ 10%, until the increase was < 10% (nonresponsive). RESULTS: A total of 157 volume loading steps were performed in the 48 patients. Responsive and nonresponsive steps differed significantly in baseline values of blood pressure, heart rate and SVV. Significant correlations were found between the change in stroke volume after fluid loading and values of blood pressure, heart rate and SVV before fluid loading, with SVV the most sensitive variable. CONCLUSION: Stroke volume variation obtained using the FloTrac™/Vigileo™ system is a sensitive predictor of fluid responsiveness in healthy patients before brain surgery.

Haemodynamic Effects of Different Beta Blockers in Angina Pectoris

1977 ◽  
Vol 22 (1) ◽  
pp. 64-68 ◽  
Author(s):  
H. Åström ◽  
B. Jonsson
Keyword(s):  
Heart Rate ◽  
Angina Pectoris ◽  
Stroke Volume ◽  
Partial Agonist ◽  
Beta Blockers ◽  
Haemodynamic Effects ◽  
Agonist Activity ◽  
Peripheral Vascular ◽  
Reduce Heart Rate ◽  
Beta Blocking

Beta-blocking agents with partial agonist activity seem to reduce heart rate at rest slightly less than those without this property. Cardio-selective drugs have no effect on stroke volume at rest contrary to the non-selective ones which will reduce it somewhat. This difference is abolished during exercise. The only difference seen during work between different beta-blockers is the effect on the peripheral vascular resistance. The selective drugs lower the arterial pressure with unchanged resistance.

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