scholarly journals Alexander Oliver Rankine, 1881-1956

1956 ◽  
Vol 2 ◽  
pp. 248-255

Alexander Oliver Rankine was born at Guildford in 1881, the son of the Rev. John Rankine, a Baptist minister. Both his father and mother were of Scottish descent. He had one brother and two sisters. He was educated at the Royal Grammar School, Guildford, after a period at a Board School. From Guildford he went with a county major scholarship to University College London, where he graduated with first class honours in physics in 1904. In 1910 he became a D.Sc. of the University. He was assistant in the Department of Physics in University College from 1904 to 1919, except for a period of war service from 1917-1918. He worked then under W. H. Bragg (later Sir William) first at Aberdour on the Firth of Forth, then at Harwich as Deputy Resident Director under Professor (then Colonel) A. S. Eve, and finally as Director of a new station at Dartmouth, or rather Kingswear. This involved some administrative responsibilities, and he showed tact and ability in handling the problems in war-time of an experimental station concerned with getting scientific gear into service. His main personal research contribution was a device, called the Photophone, for transmitting speech by means of a beam of light, but he also worked on acoustic and electromagnetic means of submarine detection. For his work in the War he received the O.B.E. Soon after the end of the War, in 1919, he was appointed Professor of Physics at Imperial College, South Kensington, in succession to Lord Rayleigh, this was the second chair in the department, Callendar holding the first. However, when Professor F. J. Cheshire retired in 1925 from the post of Director of the Technical Optics Department, Rankine was appointed to that post, which he held until 1931 when the Technical Optics Department was amalgamated with that of Physics, and he returned to his former position.

2018 ◽  
Vol 89 (10) ◽  
pp. A5.4-A6
Author(s):  
Shafei Rachelle ◽  
Foiani Martha ◽  
Heller Carolin ◽  
Heslegrave Amanda ◽  
Woollacott Ione ◽  
...  

IntroductionFrontotemporal dementia (FTD) is usually caused pathologically by either tau or TDP-43. Previous biofluid assays of TDP-43 have not so far proved to be sensitive or specific for identifying those cases with TDP-43 pathology.Material and methodsWe set out to investigate the novel TDP-43 Simoa assay (Quanterix) assay in both plasma and CSF in a cohort of patients recruited from the University College London FTD observational studies with known or likely TDP-43 pathology (17), non-TDP-43 pathology (13), and healthy controls (10).ResultsThe mean [standard deviation] plasma TDP-43 concentration was higher in those with likely TDP-43 pathology (155.1 [223.4] pg/ml) than those with non-TDP pathology (112.39 [252.9] pg/ml), and healthy controls (50.0 [23.1] pg/ml), but the differences between groups was non-significant, with substantial overlap in concentrations between all three groups. The mean CSF TDP-43 concentration was 2.9 [0.3] pg/ml in those with likely TDP-43 pathology, 2.8 [0.4] pg/ml in those with non-TDP pathology, and 3.1 [0.5] pg/ml in healthy controls. DiscussionThe assay tested in this study does not accurately distinguish between those with likely TDP-43 pathology and either disease controls or healthy individuals. There remains an urgent need to develop a better biofluid assay for pathological TDP-43.


2012 ◽  
Vol 53 (12) ◽  
pp. 2397-2404 ◽  
Author(s):  
Jonathan Sive ◽  
Kirit M. Ardeshna ◽  
Simon Cheesman ◽  
Franel le Grange ◽  
Stephen Morris ◽  
...  

1948 ◽  
Vol 6 (17) ◽  
pp. 212-218

E. Waymouth Reid, who retired from the Chair of Physiology at University College, Dundee, University of St Andrews, in 1935, after forty-six years’ service, died on 10 March 1948 at the age of eighty-five. He was born 11 October 1862 in Canterbury, the fourth son of a surgeon there, James Reid, F.R.C.S. He was educated at Sutton Vallance Grammar School, gaining eventually a Classical Scholarship to Cambridge. He matriculated at Cambridge University in 1879. In 1882 he gained a first class in Part I of the Natural Science Tripos and in 1883 a first class in Part II. During the period 1882-1883 he also acted as one of the demonstrators in the Department of Anatomy. He then decided to qualify in medicine and in 1883 he joined St Bartholomew’s Hospital, graduating in medicine in 1885. He early showed his interest in electrical reactions,, being appointed assistant ‘electrician’ at St Bartholomew’s in 1885. The same year he was elected to a Demonstratorship in Physiology at St Mary’s Hospital under A. D. Waller and in 1887 was promoted to the post of Assistant Lecturer in Physiology. Reid, during the period he was at St Mary’s, carried out in conjunction with Waller a most interesting investigation on the electrical activity of the excised mammalian heart. This investigation must have been one of the earliest pieces of research in electrocardiography in this country. His interest in physico-chemical reactions was also manifested early as in 1887 he devised a useful recording osmometer. In 1889 Reid was elected, at the early age of twenty-seven, as the first holder of the newly created Chair of Physiology at University College, Dundee, where he joined a stimulating and enthusiastic band of colleagues including Geddes, D’Arcy Thompson and Ewing. Reid was elected a Fellow of the Royal Society in 1898 and in 1904 gained the Sc.D. of his old University. The University of St Andrews conferred on him the degree of LL.D. when he retired from his Chair.


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