scholarly journals The structure of MP-4 from Mucuna pruriens at 2.22 Å resolution

Author(s):  
Abha Jain ◽  
Amit Kumar ◽  
Meha Shikhi ◽  
Ashish Kumar ◽  
Deepak T. Nair ◽  
...  

The structure of the MP-4 protein was previously determined at a resolution of 2.8 Å. Owing to the unavailability of gene-sequence information at the time, the side-chain assignment was carried out on the basis of a partial sequence available through Edman degradation, sequence homology to orthologs and electron density. The structure of MP-4 has now been determined at a higher resolution (2.22 Å) in another space group and all of the structural inferences that were presented in the previous report of the structure were validated. In addition, the present data allowed an improved assignment of side chains and enabled further analysis of the MP-4 structure, and the accuracy of the assignment was confirmed by the recently available gene sequence. The study reinforces the traditional concept that conservative interpretations of relatively low-resolution structures remain correct even with the availability of high-resolution data.

2009 ◽  
Vol 474 (1-2) ◽  
pp. 271-284 ◽  
Author(s):  
L. Tosi ◽  
P. Teatini ◽  
L. Carbognin ◽  
G. Brancolini

2021 ◽  
Author(s):  
Kyalo Richard ◽  
Elfatih M. Abdel-Rahman ◽  
Sevgan Subramanian ◽  
Johnson O. Nyasani ◽  
Michael Thiel ◽  
...  

2018 ◽  
Vol 45 (22) ◽  
pp. 12,340-12,349 ◽  
Author(s):  
Olga Engels ◽  
Brian Gunter ◽  
Riccardo Riva ◽  
Roland Klees

Proceedings ◽  
2018 ◽  
Vol 2 (7) ◽  
pp. 351 ◽  
Author(s):  
Lucie Koucká ◽  
Veronika Kopačková ◽  
Kateřina Fárová ◽  
Martin Gojda

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