In adults with oncological diseases, most PET/CT studies with 18F-FDG are performed using a scanning protocol with a reduced scanning area (r-PET/CT). In pediatric oncology, PET/CT with 18F-FDG is recommended to be performed in the «whole body» mode. We hypothesized that the use of r-PET/CT in children with Hodgkin's lymphoma (HL) may be sufficient without loss of diagnostic value. Materials and methods of research: a comparative analysis of PET/CT scanning protocols in «whole body» mode and r-PET/CT mode in children with HL was carried out. The retrospective analysis included 105 patients aged 0–18 years. All patient underwent primary whole-body PET/CT examinations at the time of initial staging and intermediate follow-up PET/CT scan after 2-cycle of chemotherapy. 210 PET/CT studies were retrospectively analyzed. Results: in 94 (89,5%) of 105 patients the identified lesions were localized within the area of the field-of-view of r-PET/CT, and additional lesions detected in 11 (10,5%) patients in the whole-body PET/CT examinations have not affected the results of staging and management. Conclusion: the detection of additional foci of pathological metabolic activity beyond r-PET/CT has no further impact on the stage of the disease, the protocol of treatment and the evaluation of the early response to the therapy. The advantage of r-PET/CT protocol is the reduction in radiation exposure and study time, which is very important for pediatric patients with HL.
An Investigation of the Required MR Bone Attenuation Correction for Quantitative Whole-Body PET/MR Imaging Using Clinical NaF PET/CT Studies
