An Investigation of the Required MR Bone Attenuation Correction for Quantitative Whole-Body PET/MR Imaging Using Clinical NaF PET/CT Studies

Objective: To analyze standardized uptake values (SUVs) using three different tube current intensities for attenuation correction on 18FNaF PET/CT scans. Materials and Methods: A total of 254 18F-NaF PET/CT studies were analyzed using 10, 20 and 30 mAs. The SUVs were calculated in volumes of interest (VOIs) drawn on three skeletal regions, namely, right proximal humeral diaphysis (RH), right proximal femoral diaphysis (RF), and first lumbar vertebra (LV1) in a total of 712 VOIs. The analyses covered 675 regions classified as normal (236 RH, 232 RF, and 207 LV1). Results: Mean SUV for each skeletal region was 3.8, 5.4 and 14.4 for RH, RF, and LV1, respectively. As the studies were grouped according to mAs value, the mean SUV values were 3.8, 3.9 and 3.7 for 10, 20 and 30 mAs, respectively, in the RH region; 5.4, 5.5 and 5.4 for 10, 20 and 30 mAs, respectively, in the RF region; 13.8, 14.9 and 14.5 for 10, 20 and 30 mAs, respectively, in the LV1 region. Conclusion: The three tube current values yielded similar results for SUV calculation.

Download Full-text

Simultaneous Whole-Body PET/MR Imaging in Comparison to PET/CT in Pediatric Oncology: Initial Results

Radiology ◽

10.1148/radiol.14131732 ◽

2014 ◽

Vol 273 (1) ◽

pp. 220-231 ◽

Cited By ~ 123

Author(s):

Jürgen F. Schäfer ◽

Sergios Gatidis ◽

Holger Schmidt ◽

Brigitte Gückel ◽

Ilja Bezrukov ◽

...

Keyword(s):

Mr Imaging ◽

Pediatric Oncology ◽

Whole Body ◽

Pet Ct ◽

Initial Results

Download Full-text

Respiration artifacts in whole-body 18F-FDG PET/CT studies with combined PET/CT tomographs employing spiral CT technology with 1 to 16 detector rows

European Journal of Nuclear Medicine and Molecular Imaging ◽

10.1007/s00259-005-1879-8 ◽

2005 ◽

Vol 32 (12) ◽

pp. 1429-1439 ◽

Cited By ~ 40

Author(s):

Thomas Beyer ◽

Sandra Rosenbaum ◽

Patrick Veit ◽

Jörg Stattaus ◽

Stefan P. Müller ◽

...

Keyword(s):

Fdg Pet ◽

Spiral Ct ◽

Whole Body ◽

Pet Ct ◽

Ct Technology ◽

18F Fdg ◽

Fdg Pet Ct ◽

Ct Studies

Download Full-text

COMPARISON OF VARIOUS 18F-FDG PET/CT ACQUISITION PROTOCOLS IN CHILDREN WITH HODGKIN’S LYMPHOMA

PEDIATRIA Journal named after G N SPERANSKY ◽

10.24110/0031-403x-2021-100-3-28-34 ◽

2021 ◽

Vol 100 (3) ◽

pp. 28-34

Author(s):

Yu.N. Likar ◽

◽

E.D. Kireeva ◽

А. Kailash ◽

M.Ya. Yadgarov ◽

...

Keyword(s):

Hodgkin’S Lymphoma ◽

Ct Scanning ◽

Early Response ◽

Diagnostic Value ◽

Hodgkin's Lymphoma ◽

Whole Body ◽

Pet Ct ◽

Scanning Area ◽

18F Fdg ◽

Ct Studies

In adults with oncological diseases, most PET/CT studies with 18F-FDG are performed using a scanning protocol with a reduced scanning area (r-PET/CT). In pediatric oncology, PET/CT with 18F-FDG is recommended to be performed in the «whole body» mode. We hypothesized that the use of r-PET/CT in children with Hodgkin's lymphoma (HL) may be sufficient without loss of diagnostic value. Materials and methods of research: a comparative analysis of PET/CT scanning protocols in «whole body» mode and r-PET/CT mode in children with HL was carried out. The retrospective analysis included 105 patients aged 0–18 years. All patient underwent primary whole-body PET/CT examinations at the time of initial staging and intermediate follow-up PET/CT scan after 2-cycle of chemotherapy. 210 PET/CT studies were retrospectively analyzed. Results: in 94 (89,5%) of 105 patients the identified lesions were localized within the area of the field-of-view of r-PET/CT, and additional lesions detected in 11 (10,5%) patients in the whole-body PET/CT examinations have not affected the results of staging and management. Conclusion: the detection of additional foci of pathological metabolic activity beyond r-PET/CT has no further impact on the stage of the disease, the protocol of treatment and the evaluation of the early response to the therapy. The advantage of r-PET/CT protocol is the reduction in radiation exposure and study time, which is very important for pediatric patients with HL.

Download Full-text