It is important measurement to design comprehensive information management system for cleaner production that can afford cleaner production techniques sever system for social. The comprehensive system will be designed and developed from cleaner production information systems and cleaner production management system. The content of this system was introduced which include systems management, information management and evaluation management. The composition of this system was described which include information input and output modules, information database module and information network module. The operation and development environmental conditions of this system were put forward from hardware and software configurations. The system will play an important roll to rapidly promote cleaner production development