Hybrid MR/near infrared imaging of the murine brain: optimization of optical fiber arrangement and use of a-priori knowledge

Author(s):  
H. Xu ◽  
H. Dehghani ◽  
B.W. Pogue ◽  
K.D. Paulsen ◽  
J.F. Dunn
2021 ◽  
Vol 11 (5) ◽  
pp. 1353 ◽  
Author(s):  
Joel J. Nunes ◽  
Richard W. Crane ◽  
David Mabwa ◽  
David Furniss ◽  
Mark Farries ◽  
...  

Atmosphere ◽  
2020 ◽  
Vol 11 (10) ◽  
pp. 1052
Author(s):  
Jian Xu ◽  
Lanlan Rao ◽  
Franz Schreier ◽  
Dmitry S. Efremenko ◽  
Adrian Doicu ◽  
...  

In atmospheric science we are confronted with inverse problems arising in applications associated with retrievals of geophysical parameters. A nonlinear mapping from geophysical quantities (e.g., atmospheric properties) to spectral measurements can be represented by a forward model. An inversion often suffers from the lack of stability and its stabilization introduced by proper approaches, however, can be treated with sufficient generality. In principle, regularization can enforce uniqueness of the solution when additional information is incorporated into the inversion process. In this paper, we analyze different forms of the regularization matrix L in the framework of Tikhonov regularization: the identity matrix L0, discrete approximations of the first and second order derivative operators L1 and L2, respectively, and the Cholesky factor of the a priori profile covariance matrix LC. Each form of L has its intrinsic pro/cons and thus may lead to different performance of inverse algorithms. An extensive comparison of different matrices is conducted with two applications using synthetic data from airborne and satellite sensors: retrieving atmospheric temperature profiles from microwave spectral measurements, and deriving aerosol properties from near infrared spectral measurements. The regularized solution obtained with L0 possesses a reasonable magnitude, but its smoothness is not always assured. The retrieval using L1 and L2 produces a solution in favor of the smoothness, and the impact of the a priori knowledge is less critical on the retrieval using L1. The retrieval performance of LC is affected by the accuracy of the a priori knowledge.


Author(s):  
Robert Audi

This book provides an overall theory of perception and an account of knowledge and justification concerning the physical, the abstract, and the normative. It has the rigor appropriate for professionals but explains its main points using concrete examples. It accounts for two important aspects of perception on which philosophers have said too little: its relevance to a priori knowledge—traditionally conceived as independent of perception—and its role in human action. Overall, the book provides a full-scale account of perception, presents a theory of the a priori, and explains how perception guides action. It also clarifies the relation between action and practical reasoning; the notion of rational action; and the relation between propositional and practical knowledge. Part One develops a theory of perception as experiential, representational, and causally connected with its objects: as a discriminative response to those objects, embodying phenomenally distinctive elements; and as yielding rich information that underlies human knowledge. Part Two presents a theory of self-evidence and the a priori. The theory is perceptualist in explicating the apprehension of a priori truths by articulating its parallels to perception. The theory unifies empirical and a priori knowledge by clarifying their reliable connections with their objects—connections many have thought impossible for a priori knowledge as about the abstract. Part Three explores how perception guides action; the relation between knowing how and knowing that; the nature of reasons for action; the role of inference in determining action; and the overall conditions for rational action.


Author(s):  
Donald C. Williams

This chapter begins with a systematic presentation of the doctrine of actualism. According to actualism, all that exists is actual, determinate, and of one way of being. There are no possible objects, nor is there any indeterminacy in the world. In addition, there are no ways of being. It is proposed that actual entities stand in three fundamental relations: mereological, spatiotemporal, and resemblance relations. These relations govern the fundamental entities. Each fundamental entity stands in parthood relations, spatiotemporal relations, and resemblance relations to other entities. The resulting picture is one that represents the world as a four-dimensional manifold of actual ‘qualitied contents’—upon which all else supervenes. It is then explained how actualism accounts for classes, quantity, number, causation, laws, a priori knowledge, necessity, and induction.


Author(s):  
Keith DeRose

In this chapter the contextualist Moorean account of how we know by ordinary standards that we are not brains in vats (BIVs) utilized in Chapter 1 is developed and defended, and the picture of knowledge and justification that emerges is explained. The account (a) is based on a double-safety picture of knowledge; (b) has it that our knowledge that we’re not BIVs is in an important way a priori; and (c) is knowledge that is easily obtained, without any need for fancy philosophical arguments to the effect that we’re not BIVs; and the account is one that (d) utilizes a conservative approach to epistemic justification. Special attention is devoted to defending the claim that we have a priori knowledge of the deeply contingent fact that we’re not BIVs, and to distinguishing this a prioritist account of this knowledge from the kind of “dogmatist” account prominently championed by James Pryor.


Author(s):  
Ewa M. Nowara ◽  
Tim K. Marks ◽  
Hassan Mansour ◽  
Ashok Veeraraghavan

2021 ◽  
Vol 93 (5) ◽  
pp. 3035-3041
Author(s):  
Zhao Wang ◽  
Weiwei Wang ◽  
Pengzhan Wang ◽  
Xinjian Song ◽  
Zhiqiang Mao ◽  
...  

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