Intervention in Gene Regulatory Networks via a Stationary Mean-First-Passage-Time Control Policy

2008 ◽  
Vol 55 (10) ◽  
pp. 2319-2331 ◽  
Author(s):  
Golnaz Vahedi ◽  
Babak Faryabi ◽  
Jean-Francois Chamberland ◽  
Aniruddha Datta ◽  
Edward R. Dougherty
Keyword(s):  
Gene Regulatory Networks ◽  
Regulatory Networks ◽  
First Passage Time ◽  
Control Policy ◽  
Passage Time ◽  
Mean First Passage Time ◽  
First Passage ◽  
Time Control ◽  
Gene Regulatory

scholarly journals Mean first-passage time of a tumor cell growth system with time delay and colored cross-correlated noises excitation

2017 ◽  
Vol 37 (2) ◽  
pp. 191-198 ◽  
Author(s):  
Shenghong Li ◽  
Yong Huang
Keyword(s):  
Time Delay ◽  
Noise Intensity ◽  
First Passage Time ◽  
Passage Time ◽  
Mean First Passage Time ◽  
Tumor Cell Growth ◽  
First Passage ◽  
Growth System ◽  
The Mean ◽  
Correlated Noises

In this paper, the mean first-passage time of a delayed tumor cell growth system driven by colored cross-correlated noises is investigated. Based on the Novikov theorem and the method of probability density approximation, the stationary probability density function is obtained. Then applying the fastest descent method, the analytical expression of the mean first-passage time is derived. Finally, effects of different kinds of delays and noise parameters on the mean first-passage time are discussed thoroughly. The results show that the time delay included in the random force, additive noise intensity and multiplicative noise intensity play a positive role in the disappearance of tumor cells. However, the time delay included in the determined force and the correlation time lead to the increase of tumor cells.

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