A dynamic random-effects model for recovery of skin barrier function: evaluation of the efficacy of different skin care products

Author(s):  
Mogens Erlandsen ◽  
Lars Halkier-Sørensen
2019 ◽  
Vol 7 (3) ◽  
pp. 134-136
Author(s):  
Markus Braun-Falco

In order to maintain skin in «good condition» one can use cosmetic products. Importantly, those skin care products should fulfil specific requirements for specific life phases and specific skin conditions. In this review, we focused on 2 different age groups - namely, infants and the elderly - as well as on 2 specific skin conditions occurring in both age groups - very dry skin (Xerosis) and hyperhydrated skin (diaper rash). The goal in both conditions should be to maintain skin surface in its physiological acidic state, which is in turn crucial for the permeability barrier function, stratum corneum integrity/cohesion and antimicrobial defense. Skin care products formulated with an effective buffer system at a more acidic pH, for example 4, may be the best option to improve the acid mantle and skin barrier function and thus keep the skin in «good condition».


2010 ◽  
Vol 27 (1) ◽  
pp. 1-8 ◽  
Author(s):  
Natalie Garcia Bartels ◽  
Ramona Scheufele ◽  
Franziska Prosch ◽  
Tania Schink ◽  
Hans Proquitté ◽  
...  

2018 ◽  
Vol 4 ◽  
pp. 237796081878205
Author(s):  
Keiko Kimori ◽  
Chizuko Konya ◽  
Masaru Matsumoto

We aimed to compare the barrier function of the skin site with the color of hematoma induced by venipuncture and the area surrounding the skin site to help improve skin care for hospitalized elderly patients. There were 50 patients with a median age of 84 years who were included in the analysis. There was no significant difference between the hematoma site-induced venipuncture and the area surrounding the hematoma site in terms of transepidermal water loss and skin sebum level. The status of stratum corneum hydration and skin elasticity on the hematoma sites was significantly lower than that on nonhematoma sites. The median skin pH was significantly higher on hematoma sites than that on nonhematoma sites. The study variables did not reveal any significant correlation with the intensity of skin erythema. These findings showed that hematoma formation in the subcutaneous tissue affected the skin barrier function and that these sites need moisturizing skin care regardless of the intensity of skin erythema.


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