89% Vichy mineralizing water with hyaluronic acid is a well‐tolerated adjunct treatment that helps restore skin barrier function in dry skin‐related inflammatory dermatoses and post‐procedure skin care: A Canadian study

Dry and eczema-prone skin conditions such as atopic dermatitis and xerotic eczema primarily indicate an impaired skin barrier function, which leads to chronic pruritus. Here, we investigated the effects of a novel emollient containing H.ECMTM liposome, which contains a soluble proteoglycan in combination with hydrolyzed collagen and hyaluronic acid. A prospective, single-arm study was conducted on 25 participants with mild atopic dermatitis or dry skin to assess the hydration and anti-inflammatory effect of the novel emollient applied daily over four weeks. All efficacy parameters, including itching severity, transepidermal water loss, and skin hydration, improved significantly after four weeks. The in vitro and ex vivo studies confirmed the restoration of the skin’s barrier function. The study revealed the clinical and laboratory efficacy of H.ECMTM liposome in reducing itching and improving the skin’s barrier integrity. Thus, the use of H.ECMTM liposome can be considered a therapeutic option for dry and eczema-prone skin.

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Bathing in a magnesium-rich Dead Sea salt solution improves skin barrier function, enhances skin hydration, and reduces inflammation in atopic dry skin

International Journal of Dermatology ◽

10.1111/j.1365-4632.2005.02079.x ◽

2005 ◽

Vol 44 (2) ◽

pp. 151-157 ◽

Cited By ~ 71

Author(s):

Ehrhardt Proksch ◽

Hans-Peter Nissen ◽

Markus Bremgartner ◽

Colin Urquhart

Keyword(s):

Salt Solution ◽

Barrier Function ◽

Skin Barrier ◽

Dead Sea ◽

Sea Salt ◽

Skin Hydration ◽

Skin Barrier Function ◽

Dry Skin

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Die Rolle des pH-Wertes bei Intertrigo oder zu trockener Haut

Karger Kompass Dermatologie ◽

10.1159/000496130 ◽

2019 ◽

Vol 7 (3) ◽

pp. 134-136

Author(s):

Markus Braun-Falco

Keyword(s):

Barrier Function ◽

Good Condition ◽

Age Groups ◽

Skin Barrier ◽

Skin Care ◽

Skin Barrier Function ◽

Permeability Barrier ◽

Buffer System ◽

Skin Conditions ◽

Skin Care Products

In order to maintain skin in «good condition» one can use cosmetic products. Importantly, those skin care products should fulfil specific requirements for specific life phases and specific skin conditions. In this review, we focused on 2 different age groups - namely, infants and the elderly - as well as on 2 specific skin conditions occurring in both age groups - very dry skin (Xerosis) and hyperhydrated skin (diaper rash). The goal in both conditions should be to maintain skin surface in its physiological acidic state, which is in turn crucial for the permeability barrier function, stratum corneum integrity/cohesion and antimicrobial defense. Skin care products formulated with an effective buffer system at a more acidic pH, for example 4, may be the best option to improve the acid mantle and skin barrier function and thus keep the skin in «good condition».

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Venipuncture-Induced Hematomas Alter Skin Barrier Function in the Elderly Patients

SAGE Open Nursing ◽

10.1177/2377960818782050 ◽

2018 ◽

Vol 4 ◽

pp. 237796081878205

Author(s):

Keiko Kimori ◽

Chizuko Konya ◽

Masaru Matsumoto

Keyword(s):

Elderly Patients ◽

Barrier Function ◽

Subcutaneous Tissue ◽

Skin Barrier ◽

Transepidermal Water Loss ◽

Skin Care ◽

Skin Barrier Function ◽

Skin Site ◽

Significant Difference ◽

Skin Erythema

We aimed to compare the barrier function of the skin site with the color of hematoma induced by venipuncture and the area surrounding the skin site to help improve skin care for hospitalized elderly patients. There were 50 patients with a median age of 84 years who were included in the analysis. There was no significant difference between the hematoma site-induced venipuncture and the area surrounding the hematoma site in terms of transepidermal water loss and skin sebum level. The status of stratum corneum hydration and skin elasticity on the hematoma sites was significantly lower than that on nonhematoma sites. The median skin pH was significantly higher on hematoma sites than that on nonhematoma sites. The study variables did not reveal any significant correlation with the intensity of skin erythema. These findings showed that hematoma formation in the subcutaneous tissue affected the skin barrier function and that these sites need moisturizing skin care regardless of the intensity of skin erythema.

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