scholarly journals The monoamine stabilizer (−)‐OSU6162 prevents the alcohol deprivation effect and improves motor impulsive behavior in rats

2018 ◽  
Vol 24 (3) ◽  
pp. 471-484 ◽  
Author(s):  
Ida Fredriksson ◽  
Malin Wirf ◽  
Pia Steensland
Keyword(s):  
Impulsive Behavior ◽  
Alcohol Deprivation Effect ◽  
Deprivation Effect

Development of an Alcohol-Deprivation Effect in Rats

1968 ◽  
Vol 29 (4) ◽  
pp. 863-867 ◽  
Author(s):  
J. D. Sinclair ◽  
R. J. Senter
Keyword(s):  
Alcohol Deprivation Effect ◽  
Deprivation Effect

The role of the NMDA receptor in alcohol relapse: a pharmacological mapping study using the alcohol deprivation effect

2005 ◽  
Vol 48 (6) ◽  
pp. 822-829 ◽  
Author(s):  
Valentina Vengeliene ◽  
Daniel Bachteler ◽  
Wojciech Danysz ◽  
Rainer Spanagel
Keyword(s):  
Nmda Receptor ◽  
Mapping Study ◽  
Alcohol Deprivation Effect ◽  
Alcohol Relapse ◽  
Deprivation Effect

INCREASED MOTIVATION TO WORK FOR ALCOHOL DURING THE ALCOHOL DEPRIVATION EFFECT

1999 ◽  
Vol 10 (SUPPLEMENT 1) ◽  
pp. S48 ◽  
Author(s):  
Sabine M. H??lter
Keyword(s):  
Alcohol Deprivation Effect ◽  
Deprivation Effect ◽  
Motivation To Work

Lack of alcohol-deprivation effect in AA rats

Alcohol ◽  
1988 ◽  
Vol 5 (1) ◽  
pp. 85-87 ◽  
Author(s):  
J.D. Sinclair ◽  
K. Tiihonen
Keyword(s):  
Alcohol Deprivation Effect ◽  
Deprivation Effect

scholarly journals Increased alcohol consumption in rats after subchronic antidepressant treatment

2013 ◽  
Vol 16 (8) ◽  
pp. 1809-1818 ◽  
Author(s):  
Francisco Alén ◽  
Laura Orio ◽  
Miguel Á Gorriti ◽  
Raquel Gómez de Heras ◽  
María Teresa Ramírez-López ◽  
...  
Keyword(s):  
Alcohol Consumption ◽  
Antidepressant Treatment ◽  
Challenge Dose ◽  
Dopaminergic Transmission ◽  
Reward Circuitry ◽  
Alcohol Deprivation Effect ◽  
Fluoxetine Treatment ◽  
Co Morbidity ◽  
Deprivation Effect ◽  
Increase Alcohol Consumption

AbstractThe use of antidepressants for alcoholism in humans has been a matter of controversy in recent years. Despite the existence of an important co-morbidity for depression and alcoholism, some studies suggest that the use of antidepressants could worsen the prognosis of alcoholism. However, there is a lack of studies in animal models exploring this phenomenon. In the present study, we show how the 15-d treatment with fluoxetine (10 mg/kg) or venlafaxine (50 mg/kg) affected alcohol deprivation effect (ADE) and subsequent alcohol consumption. Initially, fluoxetine reduced ADE and venlafaxine did not affect it. However, in the following days, both antidepressants increased alcohol consumption, an effect that was found to last at least 5 wk. Fluoxetine treatment was shown to cause a locomotor sensitized response to a challenge dose of amphetamine (0.5 mg/kg), indicating the presence of a supersensitive dopaminergic transmission. In summary, antidepressant treatment may increase alcohol consumption in rats after a period of alcohol deprivation and this could be related to alterations in the reward circuitry. This finding confirms in an animal model previous reports in humans that may limit the use of antidepressants for alcoholism.

The alcohol deprivation effect model for studying relapse behavior: A comparison between rats and mice

Alcohol ◽  
2014 ◽  
Vol 48 (3) ◽  
pp. 313-320 ◽  
Author(s):  
Valentina Vengeliene ◽  
Ainhoa Bilbao ◽  
Rainer Spanagel
Keyword(s):  
Alcohol Deprivation Effect ◽  
Effect Model ◽  
Deprivation Effect ◽  
Rats And Mice

C-FOS MAPPING AND GENE EXPRESSION PROFILES IN RATS UNDERGOING ALCOHOL DEPRIVATION EFFECT.

2004 ◽  
Vol 28 (Supplement) ◽  
pp. 16A
Author(s):  
F Leonardi-Essmann ◽  
V Vengeliene ◽  
P Gass ◽  
P Gebicke-Haerter ◽  
R Spanagel
Keyword(s):  
Gene Expression ◽  
Expression Profiles ◽  
Gene Expression Profiles ◽  
Alcohol Deprivation Effect ◽  
Deprivation Effect

scholarly journals The selective κ-opioid receptor antagonist JDTic attenuates the alcohol deprivation effect in rats

2019 ◽  
Vol 29 (12) ◽  
pp. 1386-1396 ◽  
Author(s):  
Johanna Uhari-Väänänen ◽  
Tony Eteläinen ◽  
Pia Bäckström ◽  
Ville Oinio ◽  
F. Ivy Carroll ◽  
...  
Keyword(s):  
Receptor Antagonist ◽  
Opioid Receptor ◽  
Alcohol Deprivation Effect ◽  
Opioid Receptor Antagonist ◽  
Deprivation Effect
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