Heavy episodic drinking and deliberate self-harm in young people: a longitudinal cohort study

ObjectivesIn England, healthcare policy advocates specialised age-appropriate services for teenagers and young adults (TYA), those aged 13 to 24 years at diagnosis. Specialist Principal Treatment Centres (PTC) provide enhanced TYA age-specific care, although many still receive care in adult or children’s cancer services. We present the first prospective structured analysis of quality of life (QOL) associated with the amount of care received in a TYA-PTCDesignLongitudinal cohort study.SettingHospitals delivering inpatient cancer care in England.Participants1114 young people aged 13 to 24 years newly diagnosed with cancer.InterventionExposure to the TYA-PTC defined as patients receiving NO-TYA-PTC care with those receiving ALL-TYA-PTC and SOME-TYA-PTC care.Primary outcomeQuality of life measured at five time points: 6, 12, 18, 24 and 36 months after diagnosis.ResultsGroup mean total QOL improved over time for all patients, but for those receiving NO-TYA-PTC was an average of 5.63 points higher (95% CI 2.77 to 8.49) than in young people receiving SOME-TYA-PTC care, and 4·17 points higher (95% CI 1.07 to 7.28) compared with ALL-TYA-PTC care. Differences were greatest 6 months after diagnosis, reduced over time and did not meet the 8-point level that is proposed to be clinically significant. Young people receiving NO-TYA-PTC care were more likely to have been offered a choice of place of care, be older, from more deprived areas, in work and have less severe disease. However, analyses adjusting for confounding factors did not explain the differences between TYA groups.ConclusionsReceipt of some or all care in a TYA-PTC was associated with lower QOL shortly after cancer diagnosis. The NO-TYA-PTC group had higher QOL 3 years after diagnosis, however those receiving all or some care in a TYA-PTC experienced more rapid QOL improvements. Receipt of some care in a TYA-PTC requires further study.

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Modelling associations between neurocognition and functional course in young people with emerging mental disorders: a longitudinal cohort study

Translational Psychiatry ◽

10.1038/s41398-020-0726-9 ◽

2020 ◽

Vol 10 (1) ◽

Cited By ~ 6

Author(s):

Jacob J. Crouse ◽

Kate M. Chitty ◽

Frank Iorfino ◽

Joanne S. Carpenter ◽

Django White ◽

...

Keyword(s):

Cohort Study ◽

Young People ◽

Mental Disorders ◽

Longitudinal Cohort Study ◽

Longitudinal Cohort

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Faculty Opinions recommendation of Bullying victimisation and risk of self harm in early adolescence: longitudinal cohort study.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.716747952.792103004 ◽

2012 ◽

Author(s):

Christian Schmahl ◽

Annegret Krause-Utz

Keyword(s):

Cohort Study ◽

Early Adolescence ◽

Longitudinal Cohort Study ◽

Longitudinal Cohort ◽

Self Harm ◽

Bullying Victimisation

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Optimizing a Retention Strategy with Young People for BRIGHTLIGHT, a Longitudinal Cohort Study Examining the Value of Specialist Cancer Care for Young People

Journal of Adolescent and Young Adult Oncology ◽

10.1089/jayao.2016.0085 ◽

2017 ◽

Vol 6 (3) ◽

pp. 459-469 ◽

Cited By ~ 8

Author(s):

Rachel M. Taylor ◽

Natasha Aslam ◽

Sarah Lea ◽

Jeremy S. Whelan ◽

Lorna A. Fern

Keyword(s):

Cohort Study ◽

Young People ◽

Cancer Care ◽

Longitudinal Cohort Study ◽

Retention Strategy ◽

Longitudinal Cohort

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Risk of depression and self-harm in teenagers identifying with goth subculture: a longitudinal cohort study

The Lancet Psychiatry ◽

10.1016/s2215-0366(15)00164-9 ◽

2015 ◽

Vol 2 (9) ◽

pp. 793-800 ◽

Cited By ~ 17

Author(s):

Lucy Bowes ◽

Rebecca Carnegie ◽

Rebecca Pearson ◽

Becky Mars ◽

Lucy Biddle ◽

...

Keyword(s):

Cohort Study ◽

Longitudinal Cohort Study ◽

Longitudinal Cohort ◽

Self Harm

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Development of an individualized risk calculator for poor functioning in young people victimized during childhood: A longitudinal cohort study

Child Abuse & Neglect ◽

10.1016/j.chiabu.2019.104188 ◽

2019 ◽

Vol 98 ◽

pp. 104188 ◽

Cited By ~ 2

Author(s):

Rachel M. Latham ◽

Alan J. Meehan ◽

Louise Arseneault ◽

Daniel Stahl ◽

Andrea Danese ◽

...

Keyword(s):

Cohort Study ◽

Young People ◽

Longitudinal Cohort Study ◽

Risk Calculator ◽

Longitudinal Cohort

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Suicide and self-harm trends in recent immigrant youth in Ontario, 1996-2012: a population-based longitudinal cohort study

BMJ Open ◽

10.1136/bmjopen-2016-014863 ◽

2017 ◽

Vol 7 (9) ◽

pp. e014863 ◽

Cited By ~ 9

Author(s):

Natasha Ruth Saunders ◽

Michael Lebenbaum ◽

Therese A Stukel ◽

Hong Lu ◽

Marcelo L Urquia ◽

...

Keyword(s):

Cohort Study ◽

Immigrant Youth ◽

Population Based ◽

Longitudinal Cohort Study ◽

Refugee Status ◽

Longitudinal Cohort ◽

Recent Immigrant ◽

Suicide Rates ◽

Self Harm ◽

Over Time

ObjectiveTo describe the trends in suicide and emergency department (ED) visits for self-harm in youth by immigration status and immigrant characteristics.DesignPopulation-based longitudinal cohort study from 1996 to 2012 using linked health and administrative datasets.SettingOntario, Canada.ParticipantsYouth 10 to 24 years, living in Ontario, Canada.ExposureThe main exposure was immigrant status (recent immigrant (RI) versus long-term residents (LTR)). Secondary exposures included region of birth, duration or residence, and refugee status.Main outcome measureTrends over time in suicide and ED self-harm were modelled within consecutive 3-year time periods. Rate ratios were estimated using Poisson regression models.Results2.5 to 2.9 million individuals were included per cohort period. LTR suicide rates ranged from 7.4 to 9.4/100 000 male person-years versus 2.2–3.4/100 000 females. RI’s suicide rates were 2.7–7.2/100,000 male versus 1.9–2.7/100 000 female person-years. Suicide rates were lower among RI compared with LTR (adjusted relative rate (aRR)=0.70, 95% CI=0.57 to 0.85) with different mechanisms of suicide. No significant time trend in suicide rates was observed (p=0.40). ED self-harm rates for LTR and RI were highest in females (2.6–3.4/1000 LTR females versus 1.1–1.5/1000 males, 1.2–1.8/1000 RI females versus 0.4–0.6/1000 males). RI had lower rates of self-harm compared with LTR (aRR=0.60, 95% CI=0.56 to 0.65). Stratum-specific rates showed a steeper decline per period in RI compared with LTR (RI: aRR=0.85, 95% CI=0.81 to 0.89; LTR: aRR=0.91, 95% CI=0.90 to 0.93). Observed trends were not universal across region of origin and by refugee status.InterpretationSuicide rates have been stable and ED self-harm rates are declining over time among RI youth. These trends by important subgroups should continue to be monitored to allow for early identification of subpopulations of immigrant youth in need of targeted and culturally appropriate public health interventions.

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