scholarly journals Nasal specific IgE correlates to serum specific IgE: First steps towards nasal molecular allergy diagnostic

Allergy ◽  
2020 ◽  
Vol 75 (7) ◽  
pp. 1802-1805
Author(s):  
Mehmet Gökkaya ◽  
Vera Schwierzeck ◽  
Karisa Thölken ◽  
Stephan Knoch ◽  
Michael Gerstlauer ◽  
...  
Keyword(s):  
Specific Ige ◽  
Molecular Allergy

Comparison between two automated systems to determine specific IgE: CAP and ELItest

1996 ◽  
Vol 26 (12) ◽  
pp. 1420-1427 ◽  
Author(s):  
T. BRUNNEE ◽  
A. SEEBERGER ◽  
J. KLEINE-TEBBE ◽  
G. KUNKEL
Keyword(s):  
Specific Ige ◽  
Automated Systems

Comparison between an intradermal skin test and allergen-specific IgE-ELISA for canine atopic dermatitis

2008 ◽  
Vol 150 (3) ◽  
pp. 117-122 ◽  
Author(s):  
N. Tarpataki ◽  
B. Bigler ◽  
P. Vajdovich ◽  
K. Vörös
Keyword(s):  
Atopic Dermatitis ◽  
Skin Test ◽  
Specific Ige ◽  
Canine Atopic Dermatitis

Diagnostic utility of changes in egg-specific IgE in infants with atopic dermatitis

2017 ◽  
Vol 31 (5) ◽  
pp. 692-698
Author(s):  
Chiho Tatsumoto ◽  
Mizuho Nagao ◽  
Takao Fujisawa
Keyword(s):  
Atopic Dermatitis ◽  
Specific Ige ◽  
Diagnostic Utility

CORRELATION OF SERUM SPECIFIC IGE AND SKIN PRICK TESTS IN CHILDREN WITH RESPIRATORY ALLERGY

2011 ◽  
Author(s):  
Esen Demir ◽  
Levent Midyat ◽  
Figen Gulen ◽  
Gulhadiye Akbas ◽  
Sema Tanrıverdi ◽  
...  
Keyword(s):  
Specific Ige ◽  
Respiratory Allergy ◽  
Skin Prick Tests

Component resolved diagnostics in peanut sensitized children with and without a history of clinical reaction

2020 ◽  
Vol 41 (5) ◽  
pp. 336-340
Author(s):  
Yasmin Hamzavi Abedi ◽  
Cristina P. Sison ◽  
Punita Ponda
Keyword(s):  
Retrospective Chart Review ◽  
Clinical History ◽  
Specific Ige ◽  
Exact Test ◽  
Ara H 1 ◽  
Sige Level ◽  
History Of ◽  
Laboratory Procedures ◽  
Ige Mediated ◽  
The Relationship

Background: Serum Peanut-specific-IgE (PN-sIgE) and peanut-component-resolved-diagnostics (CRD) are often ordered simultaneously in the evaluation for peanut allergy. Results often guide the plans for peanut oral challenge. However, the clinical utility of CRD at different total PN-sIgE levels is unclear. A commonly used predefined CRD Ara h2 cutoff value in the literature predicting probability of peanut challenge outcomes is 0.35kUA/L. Objective: To examine the utility of CRD in patients with and without a history of clinical reactivity to peanut (PN). Methods: This was a retrospective chart review of 196 children with PN-sIgE and CRD testing, of which, 98 patients had a clinical history of an IgE-mediated reaction when exposed to PN and 98 did not. The Fisher's exact test was used to assess the relationship between CRD and PN-sIgE at different cutoff levels, McNemar test and Gwet’s approach (AC1 statistic) were used to examine agreement between CRD and PN-sIgE, and logistic regression was used to assess differences in the findings between patients with and without reaction history. Results: Ara h 1, 2, 3, or 9 (ARAH) levels ≤0.35 kUA/L were significantly associated with PN-sIgE levels <2 kUA/L rather than ≥2 kUA/L (p < 0.0001). When the ARAH threshold was increased to 1 kUA/L and 2 kUA/L, these thresholds were still significantly associated with PN-sIgE levels of <2, <5, and <14 kUA/L. These findings were not significantly different in patients with and without a history of clinical reactivity. Conclusion: ARAH values correlated with PN-sIgE. Regardless of clinical history, ARAH levels are unlikely to be below 0.35, 1, or 2 kUA/L if the PN-sIgE level is >2 kUA/L. Thus, if possible, practitioners should consider PN-sIgE rather than automatically ordering CRD with PN-sIgE every time. Laboratory procedures that allow automatically and reflexively adding CRD when the PN-sIgE level is ≤5 kUA/L can be helpful. However, further studies are needed in subjects with challenge-proven PN allergy.

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