Comparison on the properties of bovine pericardium and porcine pericardium used as leaflet materials of transcatheter heart valve

2021 ◽  
Author(s):  
Chang Jin ◽  
Li Zhao ◽  
Zebin Wu ◽  
Bin Li ◽  
Ronghui Liu ◽  
...  
Keyword(s):  
Heart Valve ◽  
Bovine Pericardium ◽  
Transcatheter Heart Valve ◽  
Porcine Pericardium

scholarly journals Yak Pericardium as an Alternative Biomaterial for Transcatheter Heart Valves

2021 ◽  
Vol 9 ◽  
Author(s):  
Mingzhe Song ◽  
Zhenjie Tang ◽  
Yuhong Liu ◽  
Xinlong Xie ◽  
Xiaoke Qi ◽  
...  
Keyword(s):  
Mechanical Properties ◽  
Heart Valves ◽  
Amino Acid Content ◽  
Bovine Pericardium ◽  
Elastic Fibers ◽  
Transcatheter Aortic Valve ◽  
Transcatheter Heart Valve ◽  
Valve Implantation ◽  
Porcine Pericardium

Transcatheter aortic valve implantation (TAVI) has received much attention and development in the past decade due to its lower risk of complication and infections compared to a traditional open thoracotomy. However, the current commercial transcatheter heart valve does not fully meet clinical needs; therefore, new biological materials must be found in order to meet these requirements. We have discovered a new type of biological material, the yak pericardium. This current research studied its extracellular matrix structure, composition, mechanical properties, and amino acid content. Folding experiment was carried out to analyze the structure and mechanics after folding. We also conducted a subcutaneous embedding experiment to analyze the inflammatory response and calcification after implantation. Australian bovine pericardium, local bovine pericardium, and porcine pericardium were used as controls. The overall structure of the yak pericardium is flat, the collagen runs regularly, it has superior mechanical properties, and the average thickness is significantly lower than that of the Australian bovine and the local bovine pericardium control groups. The yak pericardium has a higher content of elastic fibers, showing that it has a better compression resistance effect during the folding experiment as well as having less expression of transplantation-related antigens. We conducted in vivo experiments and found that the yak pericardium has less inflammation and a lower degree of calcification. In summary, the yak pericardium, which is thin and strong, has lower immunogenicity and outstanding anti-calcification effects may be an excellent candidate valve leaflet material for TAVI.

Cuspal Dehiscence at a Post and Along the Stent Cloth in a Bovine Pericardium Heart Valve Implanted for Seven Years

2012 ◽  
Vol 22 (2) ◽  
pp. 95-111 ◽  
Author(s):  
Robert Guidoin ◽  
Taniela Marli Bes ◽  
Tomas Francisco Cianciulli ◽  
Julianne Klein ◽  
Bin Li ◽  
...  
Keyword(s):  
Heart Valve ◽  
Bovine Pericardium

scholarly journals Case report: Buddy wire technique to facilitate atrial septal crossing during transcatheter transseptal mitral valve implantation

2020 ◽  
Author(s):  
Ashvarya Mangla ◽  
Ameer Musa ◽  
Clifford J Kavinsky ◽  
Hussam S Suradi
Keyword(s):  
Heart Failure ◽  
Mitral Valve ◽  
Heart Valve ◽  
Interatrial Septum ◽  
Chronic Obstructive ◽  
Mitral Valve Stenosis ◽  
Heart Team ◽  
Transcatheter Heart Valve ◽  
Valve Implantation ◽  
Buddy Wire

Abstract Background Transcatheter mitral valve-in-valve implantation (MVIV) has emerged as a viable treatment option in patients at high risk for surgery. Occasionally, despite appropriate puncture location and adequate dilation, difficulty is encountered in advancing the transcatheter heart valve across interatrial septum. Case summary We describe a case of a 79-year-old woman with severe chronic obstructive pulmonary disease (COPD), prior surgical bioprosthetic aortic and mitral valve replacement implanted in 2007, atrial fibrillation, and Group II pulmonary hypertension who presented with progressively worsening heart failure symptoms secondary to severe bioprosthetic mitral valve stenosis and moderate-severe mitral regurgitation. Her symptoms had worsened over several months, with multiple admissions at other institutions with treatment for both COPD exacerbation and heart failure. Transoesophageal echocardiogram demonstrated preserved ejection fraction, normal functioning aortic valve, and dysfunctional mitral prosthesis with severe stenosis (mean gradient 13 mmHg) and moderate-severe regurgitation. After a multi-disciplinary heart team discussion, the patient underwent a transcatheter MVIV implantation. During the case, inability in advancing the transcatheter heart valve (THV) across interatrial septum despite adequate septal balloon pre-dilation was successfully managed with the support of a stiff ‘buddy wire’ anchored in the left upper pulmonary vein using the same septal puncture. The patient tolerated the procedure well and was discharged home. Discussion Operators should be aware of potential strategies to advance the THV when difficulty is encountered in crossing the atrial septum despite adequate septal preparation. One such strategy is the use of stiff ‘buddy wire’ for support which avoids the need for more aggressive septal dilatation.

Non-Nominal Deployment of the SAPIEN 3 Transcatheter Heart Valve: An Ex Vivo Bench Study

2021 ◽  
Vol 30 ◽  
pp. S314
Author(s):  
K. Bhatia ◽  
H. Sritharan ◽  
B. Gautam ◽  
N. Mughal ◽  
A. Ekmejian ◽  
...  
Keyword(s):  
Heart Valve ◽  
Ex Vivo ◽  
Bench Study ◽  
Transcatheter Heart Valve ◽  
Sapien 3
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