Glycyrrhizin has a high likelihood to be a victim of drug-drug interactions mediated by hepatic organic anion-transporting polypeptide 1B1/1B3

British Journal of Pharmacology ◽

10.1111/bph.14393 ◽

2018 ◽

Vol 175 (17) ◽

pp. 3486-3503 ◽

Author(s):

Jiajia Dong ◽

Olajide E Olaleye ◽

Rongrong Jiang ◽

Jing Li ◽

Chuang Lu ◽

...

Keyword(s):

Drug Interactions ◽

Organic Anion ◽

High Likelihood ◽

Organic Anion Transporting Polypeptide

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pH Dependence of Organic Anion-Transporting Polypeptide 2B1 in Caco-2 Cells: Potential Role in Antiretroviral Drug Oral Bioavailability and Drug–Drug Interactions

Journal of Pharmacology and Experimental Therapeutics ◽

10.1124/jpet.110.166314 ◽

2010 ◽

Vol 334 (3) ◽

pp. 1009-1022 ◽

Author(s):

Olena Kis ◽

Jason A. Zastre ◽

Manisha Ramaswamy ◽

Reina Bendayan

Keyword(s):

Drug Interactions ◽

Oral Bioavailability ◽

Potential Role ◽

Ph Dependence ◽

Organic Anion ◽

Organic Anion Transporting Polypeptide ◽

Antiretroviral Drug

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Pitavastatin as an In Vivo Probe for Studying Hepatic Organic Anion Transporting Polypeptide-Mediated Drug–Drug Interactions in Cynomolgus Monkeys

Drug Metabolism and Disposition ◽

10.1124/dmd.113.052753 ◽

2013 ◽

Vol 41 (10) ◽

pp. 1875-1882 ◽

Author(s):

Tsuyoshi Takahashi ◽

Tatsuyuki Ohtsuka ◽

Takahiro Yoshikawa ◽

Ichiro Tatekawa ◽

Yasuhiro Uno ◽

...

Keyword(s):

Drug Interactions ◽

Organic Anion ◽

Cynomolgus Monkeys ◽

Organic Anion Transporting Polypeptide

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P-glycoprotein- and organic anion-transporting polypeptide-mediated transport of periplocin may lead to drug–herb/drug–drug interactions

Drug Design Development and Therapy ◽

10.2147/dddt.s61024 ◽

2014 ◽

pp. 475 ◽

Author(s):

Xin He ◽

Sheng Liang ◽

Fengchun Deng ◽

Haiyan Xing ◽

He Wen ◽

...

Keyword(s):

Drug Interactions ◽

Organic Anion ◽

Organic Anion Transporting Polypeptide ◽

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Quantitative Prediction of Transporter- and Enzyme-Mediated Clinical Drug-Drug Interactions of Organic Anion-Transporting Polypeptide 1B1 Substrates Using a Mechanistic Net-Effect Model

Journal of Pharmacology and Experimental Therapeutics ◽

10.1124/jpet.114.215970 ◽

2014 ◽

Vol 351 (1) ◽

pp. 214-223 ◽

Author(s):

Manthena V. Varma ◽

Yi-an Bi ◽

Emi Kimoto ◽

Jian Lin

Keyword(s):

Drug Interactions ◽

Organic Anion ◽

Quantitative Prediction ◽

Organic Anion Transporting Polypeptide ◽

Effect Model ◽

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Inhibition of Hepatic Organic Anion-Transporting Polypeptide by RNA Interference in Sandwich-Cultured Human Hepatocytes: An In Vitro Model to Assess Transporter-Mediated Drug-Drug Interactions

Drug Metabolism and Disposition ◽

10.1124/dmd.110.032995 ◽

2010 ◽

Vol 38 (9) ◽

pp. 1612-1622 ◽

Author(s):

Mingxiang Liao ◽

Arek R. Raczynski ◽

Michael Chen ◽

Bei-Ching Chuang ◽

Qing Zhu ◽

...

Keyword(s):

Rna Interference ◽

Drug Interactions ◽

In Vitro Model ◽

Organic Anion ◽

Human Hepatocytes ◽

Organic Anion Transporting Polypeptide ◽

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Biomarker‐informed model‐based risk assessment of organic anion transporting polypeptide 1B mediated drug‐drug interactions

Clinical Pharmacology & Therapeutics ◽

10.1002/cpt.2434 ◽

2021 ◽

Author(s):

Emi Kimoto ◽

Chester Costales ◽

Mark A. West ◽

Yi‐an Bi ◽

Manoli Vourvahis ◽

...

Keyword(s):

Risk Assessment ◽

Drug Interactions ◽

Organic Anion ◽

Organic Anion Transporting Polypeptide ◽

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Downregulation of Organic Anion Transporting Polypeptide (OATP) 1B1 Transport Function by Lysosomotropic Drug Chloroquine: Implication in OATP-Mediated Drug-Drug Interactions

Molecular Pharmaceutics ◽

10.1021/acs.molpharmaceut.5b00763 ◽

2016 ◽

Vol 13 (3) ◽

pp. 839-851 ◽

Author(s):

Khondoker Alam ◽

Sonia Pahwa ◽

Xueying Wang ◽

Pengyue Zhang ◽

Kai Ding ◽

...

Keyword(s):

Drug Interactions ◽

Organic Anion ◽

Transport Function ◽

Organic Anion Transporting Polypeptide

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Contribution of organic anion transporting polypeptide (OATP) 1B1 and OATP1B3 to hepatic uptake of nateglinide, and the prediction of drug-drug interactions via these transporters

Journal of Pharmacy and Pharmacology ◽

10.1111/j.2042-7158.2011.01389.x ◽

2011 ◽

Vol 64 (2) ◽

pp. 199-206 ◽

Author(s):

Toshiyuki Takanohashi ◽

Satoru Kubo ◽

Harumi Arisaka ◽

Kenji Shinkai ◽

Kazuyuki Ubukata

Keyword(s):

Drug Interactions ◽

Organic Anion ◽

Hepatic Uptake ◽

Organic Anion Transporting Polypeptide

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Comparative Evaluation of Dehydroepiandrosterone Sulfate Potential to Predict Hepatic Organic Anion Transporting Polypeptide Transporter-Based Drug-Drug Interactions

Drug Metabolism and Disposition ◽

10.1124/dmd.116.072355 ◽

2016 ◽

Vol 45 (2) ◽

pp. 224-227 ◽

Author(s):

Kei Nishizawa ◽

Takeo Nakanishi ◽

Ikumi Tamai

Keyword(s):

Drug Interactions ◽

Comparative Evaluation ◽

Organic Anion ◽

Dehydroepiandrosterone Sulfate ◽

Organic Anion Transporting Polypeptide

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Organic anion transporting polypeptide 2B1 – More than a glass-full of drug interactions

Pharmacology & Therapeutics ◽

10.1016/j.pharmthera.2018.12.009 ◽

2019 ◽

Vol 196 ◽

pp. 204-215 ◽

Author(s):

Savannah J. McFeely ◽

Lanxiang Wu ◽

Tasha K. Ritchie ◽

Jashvant Unadkat

Keyword(s):

Drug Interactions ◽

Organic Anion ◽

Organic Anion Transporting Polypeptide

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