Quantitative Prediction of Transporter- and Enzyme-Mediated Clinical Drug-Drug Interactions of Organic Anion-Transporting Polypeptide 1B1 Substrates Using a Mechanistic Net-Effect Model

2014 ◽  
Vol 351 (1) ◽  
pp. 214-223 ◽  
Author(s):  
Manthena V. Varma ◽  
Yi-an Bi ◽  
Emi Kimoto ◽  
Jian Lin
Keyword(s):  
Drug Interactions ◽  
Organic Anion ◽  
Quantitative Prediction ◽  
Organic Anion Transporting Polypeptide ◽  
Effect Model ◽  
Clinical Drug

Pitavastatin as an In Vivo Probe for Studying Hepatic Organic Anion Transporting Polypeptide-Mediated Drug–Drug Interactions in Cynomolgus Monkeys

2013 ◽  
Vol 41 (10) ◽  
pp. 1875-1882 ◽  
Author(s):  
Tsuyoshi Takahashi ◽  
Tatsuyuki Ohtsuka ◽  
Takahiro Yoshikawa ◽  
Ichiro Tatekawa ◽  
Yasuhiro Uno ◽  
...  
Keyword(s):  
Drug Interactions ◽  
Organic Anion ◽  
Cynomolgus Monkeys ◽  
Organic Anion Transporting Polypeptide

scholarly journals Glycyrrhizin has a high likelihood to be a victim of drug-drug interactions mediated by hepatic organic anion-transporting polypeptide 1B1/1B3

2018 ◽  
Vol 175 (17) ◽  
pp. 3486-3503 ◽  
Author(s):  
Jiajia Dong ◽  
Olajide E Olaleye ◽  
Rongrong Jiang ◽  
Jing Li ◽  
Chuang Lu ◽  
...  
Keyword(s):  
Drug Interactions ◽  
Organic Anion ◽  
High Likelihood ◽  
Organic Anion Transporting Polypeptide

Quantitative Prediction of Renal Transporter-Mediated Clinical Drug–Drug Interactions

2013 ◽  
Vol 10 (11) ◽  
pp. 4207-4215 ◽  
Author(s):  
Bo Feng ◽  
Susan Hurst ◽  
Yasong Lu ◽  
Manthena V. Varma ◽  
Charles J. Rotter ◽  
...  
Keyword(s):  
Drug Interactions ◽  
Quantitative Prediction ◽  
Renal Transporter ◽  
Clinical Drug
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