Design, Synthesis, Biological Screening, and Molecular Docking Studies of Piperazine-Derived Constrained Inhibitors of DPP-IV for the Treatment of Type 2 Diabetes

2014 ◽  
Vol 85 (4) ◽  
pp. 439-446 ◽  
Author(s):  
Ram N. Kushwaha ◽  
Rohit Srivastava ◽  
Akansha Mishra ◽  
Arun K. Rawat ◽  
Arvind K. Srivastava ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Molecular Docking ◽  
Docking Studies ◽  
Biological Screening ◽  
Design Synthesis ◽  
Molecular Docking Studies ◽  
Dpp Iv

scholarly journals Molecular Docking Studies of Possible Treatment of Diabetes using Vasicine against Islet Amyloid Polypeptide

2021 ◽  
Vol 9 (VI) ◽  
pp. 4202-4209
Author(s):  
Tushar Kumar
Keyword(s):  
Type 2 Diabetes ◽  
Insulin Secretion ◽  
Molecular Docking ◽  
Islet Amyloid Polypeptide ◽  
Docking Studies ◽  
Islet Amyloid ◽  
Molecular Docking Studies ◽  
The World ◽  
Treatment Of Diabetes

Diabetes is the becoming one of the most common problem all over the world. About 1 in 10 persons are suffering from diabetes and most from type 2 diabetes. It occurs due to problem in pancreas which further results defect in the insulin secretion, as insulin maintains blood glucose level. The effect of Alpha-Amyrin Acetate, Myrcene and Vasicine compounds against Islet Amyloid polypeptide (IAPP) protein was seen through molecular docking studies. IAPP acts as complementary to insulin in regulating the sugar level for the treatment of diabetes disease by virtual screening. Different tools and software used in this research were Uniprot, Pubchem, Swiss ADMS, PyRx, Auto dock Vina/MGL tool and PyMOL.

Synthesis of 2-phenyl-1H-imidazo[4,5-b]pyridine as type 2 diabetes inhibitors and molecular docking studies

2017 ◽  
Vol 26 (5) ◽  
pp. 916-928 ◽  
Author(s):  
Muhammad Taha ◽  
Nor Hadiani Ismail ◽  
Syahrul Imran ◽  
Izzatul Ainaa ◽  
Manikandan Selvaraj ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Molecular Docking ◽  
Docking Studies ◽  
Molecular Docking Studies

scholarly journals Synthesis of a 1,2,3-bistriazole derivative of embelin and evaluation of its effect on high-fat diet fed-streptozotocin-induced type 2 diabetes in rats and molecular docking studies

2020 ◽  
Vol 96 ◽  
pp. 103579 ◽  
Author(s):  
Antony Stalin ◽  
Subramani Kandhasamy ◽  
Balakrishnan Senthamarai Kannan ◽  
Rama Shanker Verma ◽  
Savarimuthu Ignacimuthu ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Molecular Docking ◽  
High Fat Diet ◽  
Docking Studies ◽  
High Fat ◽  
Molecular Docking Studies
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