Synthesis and structure‐activity relationship of L‐methionine‐coupled 1,3,4‐thiadiazole derivatives with activity against influenza virus

2021 ◽  
Author(s):  
Esra Tatar ◽  
Seda Yaldız ◽  
Necla Kulabaş ◽  
Evelien Vanderlinden ◽  
Lieve Naesens ◽  
...  
Keyword(s):  
Influenza Virus ◽  
Structure Activity Relationship ◽  
Activity Relationship ◽  
Structure Activity ◽  
Thiadiazole Derivatives ◽  
Relationship Of

Synthesis and structure-activity relationship of thiadiazole derivatives, novel nonnucleoside inhibitors of HIV-1

1995 ◽  
Vol 26 (3) ◽  
pp. A258
Author(s):  
T. Yokota ◽  
M. Fujiwara ◽  
K. Ijichi ◽  
K. Konno ◽  
Y. Hanasaki ◽  
...  
Keyword(s):  
Structure Activity Relationship ◽  
Activity Relationship ◽  
Structure Activity ◽  
Thiadiazole Derivatives ◽  
Nonnucleoside Inhibitors ◽  
Relationship Of ◽  
Hiv 1

scholarly journals Anti-influenza virus activity and structure–activity relationship of aglycoristocetin derivatives with cyclobutenedione carrying hydrophobic chains

2009 ◽  
Vol 82 (1) ◽  
pp. 89-94 ◽  
Author(s):  
Lieve Naesens ◽  
Evelien Vanderlinden ◽  
Erzsébet Rőth ◽  
József Jekő ◽  
Graciela Andrei ◽  
...  
Keyword(s):  
Influenza Virus ◽  
Structure Activity Relationship ◽  
Activity Relationship ◽  
Structure Activity ◽  
Virus Activity ◽  
Relationship Of

Synthesis and Structure-Activity Relationship of N-(3-Oxo-1-Thia-4-Azaspiro[4.5]Decan-4-Yl)Carboxamide Inhibitors of Influenza Virus Hemagglutinin Mediated Fusion

2015 ◽  
Vol 190 (7) ◽  
pp. 1075-1087 ◽  
Author(s):  
Füsun Göktaş ◽  
Evelien Vanderlinden ◽  
Lieve Naesens ◽  
Zafer Cesur ◽  
Nesrin Cesur ◽  
...  
Keyword(s):  
Influenza Virus ◽  
Structure Activity Relationship ◽  
Activity Relationship ◽  
Structure Activity ◽  
Influenza Virus Hemagglutinin ◽  
Relationship Of

Structure–activity relationship of flavonoids as influenza virus neuraminidase inhibitors and their in vitro anti-viral activities

2008 ◽  
Vol 16 (15) ◽  
pp. 7141-7147 ◽  
Author(s):  
Ai-Lin Liu ◽  
Hai-Di Wang ◽  
Simon MingYuen Lee ◽  
Yi-Tao Wang ◽  
Guan-Hua Du
Keyword(s):  
Influenza Virus ◽  
Structure Activity Relationship ◽  
Activity Relationship ◽  
Neuraminidase Inhibitors ◽  
Structure Activity ◽  
Influenza Virus Neuraminidase ◽  
Relationship Of

Structure-activity relationship of (-) mammea A/BB derivatives against Leishmania amazonensis

Planta Medica ◽  
2008 ◽  
Vol 74 (09) ◽  
Author(s):  
MA Brenzan ◽  
CV Nakamura ◽  
BPD Filho ◽  
T Ueda-Nakamura ◽  
MCM Young ◽  
...  
Keyword(s):  
Structure Activity Relationship ◽  
Leishmania Amazonensis ◽  
Activity Relationship ◽  
Structure Activity ◽  
Relationship Of

Structure Activity Relationship of Kahalalide F and its Analogs Against Fusarium Spp

Planta Medica ◽  
2008 ◽  
Vol 74 (03) ◽  
Author(s):  
N Kasanah ◽  
AG Shilabin ◽  
DE Wedge ◽  
MT Hamann
Keyword(s):  
Structure Activity Relationship ◽  
Activity Relationship ◽  
Fusarium Spp ◽  
Structure Activity ◽  
Kahalalide F ◽  
Relationship Of

STRUCTURE-ACTIVITY RELATIONSHIP OF VARIOUS ANALOGUES OF β-CORTICOTRROPHIN DETERMINED BY REFERENCE TO VARIOUS PARAMETERS IN VITRO AND IN VIVO

1969 ◽  
Vol 61 (1_Suppl) ◽  
pp. S29
Author(s):  
Pierre A. Desaulles ◽  
René Maier ◽  
Matthys Staehelin
Keyword(s):  
Structure Activity Relationship ◽  
Activity Relationship ◽  
Structure Activity ◽  
Relationship Of

Antineoplastic Activity, Structural Modification, Synthesis and Structure-activity Relationship of Dammarane-type Ginsenosides: An Overview

2019 ◽  
Vol 23 (5) ◽  
pp. 503-516 ◽  
Author(s):  
Qiang Zhang ◽  
Xude Wang ◽  
Liyan Lv ◽  
Guangyue Su ◽  
Yuqing Zhao
Keyword(s):  
Structural Modification ◽  
Gastrointestinal Disease ◽  
Structure Activity Relationship ◽  
Cerebrovascular Diseases ◽  
Activity Relationship ◽  
Cycle Arrest ◽  
Structure Activity ◽  
Wide Range ◽  
Structural Association ◽  
Relationship Of

Dammarane-type ginsenosides are a class of tetracyclic triterpenoids with the same dammarane skeleton. These compounds have a wide range of pharmaceutical applications for neoplasms, diabetes mellitus and other metabolic syndromes, hyperlipidemia, cardiovascular and cerebrovascular diseases, aging, neurodegenerative disease, bone disease, liver disease, kidney disease, gastrointestinal disease and other conditions. In order to develop new antineoplastic drugs, it is necessary to improve the bioactivity, solubility and bioavailability, and illuminate the mechanism of action of these compounds. A large number of ginsenosides and their derivatives have been separated from certain herbs or synthesized, and tested in various experiments, such as anti-proliferation, induction of apoptosis, cell cycle arrest and cancer-involved signaling pathways. In this review, we have summarized the progress in structural modification, shed light on the structure-activity relationship (SAR), and offered insights into biosynthesis-structural association. This review is expected to provide a preliminary guide for the modification and synthesis of ginsenosides.

Sign in / Sign up

Export Citation Format

Share Document