Ecthyma gangrenosum, an important cutaneous infection to recognize in the immunosuppressed patient

Candidiasis is a fungal infection caused by yeasts that belong to the genus Candida. There are over 20 species of Candida yeasts that can cause infection in humans, the most common of which is Candida albicans. Candida yeasts normally reside in the intestinal tract and can be found on mucous membranes and skin without causing infection. However, under immunocompromised conditions, Candida can cause significant infections in susceptible patients. Herein, we report a peculiar presentation of a C. albicans cutaneous infection in an immunocompetent young subject. This case widens our knowledge on the C. albicans infections both in terms of host susceptibility and cutaneous manifestations.

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Deep cutaneous infection with Mycobacterium avium- intracellulare complex in an immunosuppressed patient with dermatomyositis

British Journal of Dermatology ◽

10.1046/j.1365-2133.1998.02528.x ◽

1998 ◽

Vol 139 (5) ◽

pp. 920-922 ◽

Cited By ~ 8

Author(s):

Bedlow ◽

Vittay ◽

Stephenson ◽

Cooke ◽

Holden

Keyword(s):

Mycobacterium Avium ◽

Immunosuppressed Patient ◽

Cutaneous Infection ◽

Mycobacterium Avium Intracellulare

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Mycobacterium chelonae cutaneous infection: An opportunistic disease in an immunosuppressed patient with myasthenia gravis

IDCases ◽

10.1016/j.idcr.2020.e00817 ◽

2020 ◽

Vol 21 ◽

pp. e00817 ◽

Cited By ~ 1

Author(s):

Joana Granado ◽

Ana Cláudia Miranda ◽

Marco Fernandes ◽

Luís Santos ◽

Kamal Mansinho

Keyword(s):

Myasthenia Gravis ◽

Immunosuppressed Patient ◽

Cutaneous Infection ◽

Mycobacterium Chelonae ◽

Opportunistic Disease

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Ecthyma gangrenosum in a patient with febrile pancytopenia

Our Dermatology Online ◽

10.7241/ourd.20221.24 ◽

2022 ◽

Vol 13 (1) ◽

pp. 98-98

Author(s):

Samia Mrabat ◽

Hanane Baybay ◽

Ryme Dassouly ◽

Zakia Douhi ◽

Sara Elloudi ◽

...

Keyword(s):

Septic Shock ◽

Plasma Cells ◽

Maculopapular Rash ◽

Severe Thrombocytopenia ◽

Immunocompromised Patients ◽

Cutaneous Infection ◽

Left Flank ◽

Ecthyma Gangrenosum ◽

Dermatological Examination ◽

Hemorrhagic Bullae

Ecthyma gangrenosum (EG) is a cutaneous infection most commonly associated with Pseudomonas bacteremia and usually occurring in immunocompromised patients [1]. The infection progresses sequentially from a maculopapular rash to hemorrhagic bullae, then to necrotic ulcerations with surrounding erythema [2]. Herein, we report a case of ecthyma gangrenosum in an immunologically compromised patient. A 65-year-old female was admitted to the oncohematology department for febrile pancytopenia. Blood work revealed severe thrombocytopenia at 15,000/mm³), an absolute neutrophil count of 180 cells/mm³, and anemia. A sternal bone marrow puncture found 15% of plasma cells. Four days after the admission, the patient had a painful, quickly extending lesion on the abdomen. She described erythema that progressed to pustules, then ulcerations. On general clinical evaluation, the patient was feverish at 40°C. A dermatological examination revealed the presence of a 6 cm purpuric patch on the left flank with a central necrotic eschar (Fig. 1). The diagnosis of ecthyma gangrenosum was reached and the patient was treated with ceftazidime and vancomycin. Unfortunately, having gone into septic shock, the patient died one week later.

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