Diffuse dermal angiomatosis: a rare cause of painful ulceration in renal insufficiency

2022 ◽  
Author(s):  
Ana L. Matos ◽  
Rui Nogueira ◽  
Duarte Flor ◽  
Francisca Alves ◽  
José Cardoso ◽  
...  
Keyword(s):  
Renal Insufficiency ◽  
Painful Ulceration

Rapamycin for treatment of renal insufficiency related to calcineurin inhibitors in liver transplant recipients

2001 ◽  
Vol 120 (5) ◽  
pp. A92-A92
Author(s):  
A HABIB ◽  
B BACON ◽  
A BEFELER ◽  
S RAMRAKHIANI ◽  
S RAMRAKHIANI
Keyword(s):  
Renal Insufficiency ◽  
Liver Transplant ◽  
Calcineurin Inhibitors ◽  
Transplant Recipients ◽  
Liver Transplant Recipients

Renal Insufficiency Due to Circulatory Failure

1950 ◽  
Vol 34 (3) ◽  
pp. 641-648
Author(s):  
Arthur M. Fishberg
Keyword(s):  
Renal Insufficiency ◽  
Circulatory Failure

The Use of Desmopressin Acetate (DDAVP) as a Test of the Fibrinolytic Capacity of Patients – Analysis of Responders and Non-Responders

1982 ◽  
Vol 48 (02) ◽  
pp. 156-161 ◽  
Author(s):  
E J P Brommer ◽  
M M Barrett-Bergshoeff ◽  
R A Allen ◽  
I Schicht ◽  
R M Bertina ◽  
...  
Keyword(s):  
Renal Insufficiency ◽  
Plasminogen Activator ◽  
Vascular Endothelium ◽  
Fibrinolytic Activity ◽  
Baseline Level ◽  
Poor Response ◽  
Facial Flushing ◽  
Spontaneous Thrombosis ◽  
Type Iv ◽  
Fibrinolytic Capacity

SummaryIntravenous infusion of desmopressin (DDAVP, 0.4 μg/kg b.w. in 12’) causes an increase in the level of extrinsic plasminogen activator, measured in plasma euglobulin fractions with added C1-inactivator on fibrin plates. A poor response or no response at all was elicited in two out of 21 patients with spontaneous thrombosis, 18/38 with hyperlipoproteinaemia and 10/14 with terminal renal insufficiency requiring haemodialysis.Haemodilution during the first 30’ after starting the DDAVP-infusion occurred both in responders and in non-responders; so did haemodynamic reactions: increase in heart rate, drop in diastolic blood pressure, facial flushing. The rise of fibrinolytic activity was shown not to be associated with decreased hepatic blood flow. Normal factor VIII-rises in “non-responders” indicate the responsiveness of the receptive organs, including the hypothalamus, to DDAVP.Despite a normal baseline level of fibrinolytic activity in the blood, as occurs for instance in terminal renal insufficiency, the vascular endothelium may be refractory to stimulation. In some patients, especially in type IV hyperlipoproteinaemia, a selective defect of the release of plasminogen activator is postulated. In subjects with low fibrinolytic activity at rest, as observed in spontaneous thromboembolism and in hypertriglyceridaemia, the failure to release plasminogen activator upon stimulation with DDAVP might be a consequence of an impairment of synthesis as well.

Sign in / Sign up

Export Citation Format

Share Document