scholarly journals Retinal microvasculature impairment in patients with congenital heart disease investigated by optical coherence tomography angiography

2020 ◽  
Vol 48 (9) ◽  
pp. 1219-1228
Author(s):  
Cong Li ◽  
Pingting Zhong ◽  
Haiyun Yuan ◽  
Xinran Dong ◽  
Qingsheng Peng ◽  
...  
Keyword(s):  
Congenital Heart Disease ◽  
Optical Coherence Tomography ◽  
Heart Disease ◽  
Congenital Heart ◽  
Optical Coherence Tomography Angiography ◽  
Optical Coherence ◽  
Retinal Microvasculature

scholarly journals Improved Retinal Microcirculation After Cardiac Surgery in Patients With Congenital Heart Disease

2021 ◽  
Vol 8 ◽  
Author(s):  
Cong Li ◽  
Zhuoting Zhu ◽  
Haiyun Yuan ◽  
Pingting Zhong ◽  
Qingsheng Peng ◽  
...  
Keyword(s):  
Congenital Heart Disease ◽  
Optical Coherence Tomography ◽  
Cardiac Surgery ◽  
Heart Disease ◽  
Congenital Heart ◽  
Optical Coherence Tomography Angiography ◽  
Optical Coherence ◽  
Congenital Cardiac Surgery ◽  
Capillary Plexus ◽  
Retinal Microcirculation

Background: Microcirculatory changes in congenital heart disease (CHD) patients undergoing cardiac surgery are not fully understood. We aimed to investigate the changes of retinal microcirculation in CHD patients after cardiac surgery by optical coherence tomography angiography (OCTA) and explore the association between retinal microcirculation and surgical outcome.Methods: This prospective observational study consisted of 71 CHD patients aged ≥6 years undergoing cardiac surgery including 19 cyanotic CHD (CCHD) and 52 acyanotic CHD (ACHD). Optical coherence tomography angiography (OCTA) was used to measure vessel density (VD) and capillary density (CD) of radial peripapillary capillary (RPC) and peripapillary, VD of superficial capillary plexus (SCP) and deep capillary plexus (DCP), thickness of retinal nerve fiber layer (RNFL) and ganglion cell complex (GCC) preoperatively and 1 month postoperatively. Transthoracic echocardiography was conducted to measure macrocirculation.Results: In CCHD patients, VD and CD of RPC and peripapillary increased postoperatively (all P < 0.05). In ACHD patients, VD of peripapillary, CD of RPC and peripapillary, and RNFL thickness increased postoperatively (all P < 0.05). VD of SCP and DCP, and GCC thickness did not change significantly in CHD patients after surgery. Lower preoperative retinal microvascular density was associated with longer cardiopulmonary bypass (CPB) time and postoperative length of stay (PLOS). No correlation was found between microcirculatory and macrohemodynamic parameters (all P > 0.05).Conclusions: Improved retinal microcirculation was observed after congenital cardiac surgery and impaired preoperative retinal microvasculature was associated with prolonged CPB time and PLOS, which might provide potential information about the outcome of congenital cardiac surgery.

Retinal microvasculature in pituitary adenoma patients: is optical coherence tomography angiography useful?

2019 ◽  
Vol 98 (5) ◽  
Author(s):  
Laura Dallorto ◽  
Carlo Lavia ◽  
Arnaud‐Louis Jeannerot ◽  
Natalia Shor ◽  
Christel Jublanc ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Pituitary Adenoma ◽  
Optical Coherence Tomography Angiography ◽  
Optical Coherence ◽  
Retinal Microvasculature

Association Between Sleep Apnea Risk Score and Retinal Microvasculature Using Optical Coherence Tomography Angiography

2021 ◽  
Vol 221 ◽  
pp. 55-64
Author(s):  
Ramesh Venkatesh ◽  
Arpitha Pereira ◽  
Aditya Aseem ◽  
Kushagra Jain ◽  
Sajjan Sangai ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Sleep Apnea ◽  
Risk Score ◽  
Optical Coherence Tomography Angiography ◽  
Optical Coherence ◽  
Retinal Microvasculature

scholarly journals A practical guide to optical coherence tomography angiography interpretation

2020 ◽  
Vol 6 (1) ◽  
Author(s):  
Eugenia Custo Greig ◽  
Jay S. Duker ◽  
Nadia K. Waheed
Keyword(s):  
Optical Coherence Tomography ◽  
Optical Coherence Tomography Angiography ◽  
Image Interpretation ◽  
Age Related Macular Degeneration ◽  
Optical Coherence ◽  
Clinical Practices ◽  
Imaging Device ◽  
Age Related ◽  
Retinal Microvasculature

Abstract Background Optical coherence tomography angiography (OCTA) can image the retinal vasculature in vivo, without the need for contrast dye. This technology has been commercially available since 2014, however, much of its use has been limited to the research setting. Over time, more clinical practices have adopted OCTA imaging. While countless publications detail OCTA’s use for the study of retinal microvasculature, few studies outline OCTA’s clinical utility. Body This review provides an overview of OCTA imaging and details tips for successful interpretation. The review begins with a summary of OCTA technology and artifacts that arise from image acquisition. New methods and best practices to prevent image artifacts are discussed. OCTA has the unique ability among retinovascular imaging modalities to individually visualize each retinal plexus. Slabs offered in standard OCTA devices are reviewed, and clinical uses for each slab are outlined. Lastly, the use of OCTA for the clinical interpretation of retinal pathology, such as diabetic retinopathy and age-related macular degeneration, is discussed. Conclusion OCTA is evolving from a scientific tool to a clinical imaging device. This review provides a toolkit for successful image interpretation in a clinical setting.

scholarly journals Quantitative assessment of the retinal microvasculature using optical coherence tomography angiography

2016 ◽  
Vol 21 (6) ◽  
pp. 066008 ◽  
Author(s):  
Zhongdi Chu ◽  
Jason Lin ◽  
Chen Gao ◽  
Chen Xin ◽  
Qinqin Zhang ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Quantitative Assessment ◽  
Optical Coherence Tomography Angiography ◽  
Optical Coherence ◽  
Retinal Microvasculature

scholarly journals Assessment of Macular Capillary Perfusion by Optical Coherence Tomography Angiography on Quiescent Unilateral Anterior Pediatric Uveitis

2021 ◽  
Author(s):  
Junyan Xiao ◽  
Yi Qu ◽  
Chan Zhao ◽  
Hang Song ◽  
Anyi Liang ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Optical Coherence Tomography Angiography ◽  
Foveal Avascular Zone ◽  
Flow Density ◽  
Vascular Density ◽  
Optical Coherence ◽  
Pediatric Uveitis ◽  
Retinal Microvasculature ◽  
Capillary Plexus ◽  
Fellow Eyes

Abstract Purpose: Using spectral domain optical coherence tomography angiography (SD-OCTA) to evaluate tomographic and microvascular parameters in the macula in quiescent unilateral anterior pediatric uveitis (APU) patients.Methods: Forty-two eyes of 21 patients diagnosed with unilateral APU and 21 eyes of 21 normal controls (NC) were included in this study. 6*6 mm macular scanning mode of SD-OCTA was used for all subjects. The central macular thickness (CMT), subfoveal choroidal thickness (SFCT), vascular density (VD) of superficial capillary plexus (SCP) and the deep capillary plexus (DCP), the foveal avascular zone (FAZ) area, and choriocapillary flow density (CFD) were analyzed and compared among affected, fellow, and NC eyes. Correlation analysis were used to evaluate the potential correlating factors with CFD.Results: DCP VD and CFD were significantly lower in quiescent affected eyes as compared to fellow and NCs eyes (DCP VD both p<0.001; CDF1.0: p=0.012 and p=0.003; CDF1.5: p=0.015 and p=0.006; CDF3.0: p=0.036 and p=0.010, respectively). SCP VD, DCP VD and CMT were significantly lower in the fellow eyes as compared to NC eyes (p=0.021; p<0.001; p=0.037, respectively); CFD was negatively correlated with FAZ and CMT in affected eyes and fellow eyes. No significant differences were detected in FAZ among the 3 groups (p > .05).Conclusions: As compared to NC eyes, both retinal and choroidal microvasculature were impaired in eyes with quiescent APU; retinal microvasculature in unaffected fellow eyes of unilateral APU was also impaired. OCTA is a useful technology for detection of subclinical microvascular changes in APU and may be useful as an additional prognostic tool.

scholarly journals Comparison of Retinal Microvasculature in Patients With Alzheimer's Disease and Primary Open-Angle Glaucoma by Optical Coherence Tomography Angiography

2019 ◽  
Vol 60 (10) ◽  
pp. 3447 ◽  
Author(s):  
Przemyslaw Zabel ◽  
Jakub J. Kaluzny ◽  
Monika Wilkosc-Debczynska ◽  
Martyna Gebska-Toloczko ◽  
Karolina Suwala ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Optical Coherence Tomography ◽  
Optical Coherence Tomography Angiography ◽  
Primary Open Angle Glaucoma ◽  
Open Angle Glaucoma ◽  
Optical Coherence ◽  
Open Angle ◽  
Retinal Microvasculature
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