Zirconia is an extremely successful material for prosthetic restorations, offering attractive mechanical and optical properties. It offers several advantages for posterior restorations because it can withstand physiological posterior forces. The aim of the study was to achieve the influence of zirconia framework thickness on the mechanical behavior of all-ceramic crowns using numerical simulation. For the study a premolar was chosen in order to simulate the mechanical behavior in the components of all-ceramic crowns and teeth structures regarding to the zirconia framework thickness. Maximal Von Mises equivalent stress values were recorded in teeth and restorations. Due to the registered maximal stress values it can be concluded that it is indicated to achieve frameworks of at least 0.5 mm thickness in the premolar area. Regarding stress distribution concentration were observed in the veneer around the contact areas with the antagonists, in the framework under the functional cusp and in the oral part overall and in dentin around and under the marginal line, also oral. The biomechanical behavior of all ceramic crowns under static loads can be investigated by the finite element method.