Concurrent chemoradiotherapy with low‐dose weekly platinum agent for head and neck carcinoma

2020 ◽  
Vol 45 (6) ◽  
pp. 952-955 ◽  
Author(s):  
Masayuki Kitano ◽  
Tsuyoshi Kojima ◽  
Yusuke Okanoue ◽  
Shintaro Fujimura ◽  
Seiji Oyagi ◽  
...  
Keyword(s):  
Head And Neck ◽  
Low Dose ◽  
Concurrent Chemoradiotherapy ◽  
Head And Neck Carcinoma ◽  
Neck Carcinoma ◽  
Platinum Agent

Recurrence of Lymph Node Micrometastases After Radiotherapy for Head and Neck Carcinoma: A Propensity Score-matched Study

2021 ◽  
Vol 1 (3) ◽  
pp. 165-172
Author(s):  
YU SUZUKI ◽  
KEIICHI JINGU ◽  
EIICHI ISHIDA ◽  
TAKAKI MURATA ◽  
MASAKI KUBOZONO
Keyword(s):  
Lymph Node ◽  
Propensity Score ◽  
Head And Neck ◽  
Irradiation Dose ◽  
Concurrent Chemoradiotherapy ◽  
Head And Neck Carcinoma ◽  
Lymph Node Micrometastases ◽  
Neck Carcinoma ◽  
Matched Study ◽  
Observation Period

Background: The standard irradiation dose to the elective lymph node area (ELNA) in locally patients with advanced head and neck squamous cell carcinoma (LA-HNSCC) to control lymph node micrometastases (LN-MM) has not changed since it was empirically determined in the 1950s. We investigated the optimal irradiation dose for controlling LN-MM in ELNAs. Patients and Methods: The pattern of recurrence of LA-HNSCC was retrospectively evaluated in patients who underwent concurrent chemoradiotherapy with cisplatin or radiation therapy alone. Results: In total, 162 patients were enrolled. The median observation period was 34 months. No recurrence was found in ELNAs. After propensity score matching, a cisplatin dose of ≥200 mg/m2 yielded a significantly higher overall survival rate (p≤0.001) and locoregional control rate (p=0.034) than did a dose of <100 mg/m2. Conclusion: CCRT with a cisplatin dose of ≥200 mg/m2 can reduce the irradiation dose to 40-44 Gy at 2 Gy per fraction to control LN-MM.

Induction docetaxel and S-1 followed by concomitant radiotherapy with low-dose daily cisplatin in locally advanced head and neck carcinoma

Head & Neck ◽  
2016 ◽  
Vol 38 (S1) ◽  
pp. E1653-E1659 ◽  
Author(s):  
Hye Ryun Kim ◽  
Chang Geol Lee ◽  
Eun Chang Choi ◽  
Joo Hang Kim ◽  
Yoon Woo Koh ◽  
...  
Keyword(s):  
Head And Neck ◽  
Low Dose ◽  
Locally Advanced ◽  
Head And Neck Carcinoma ◽  
Advanced Head ◽  
Neck Carcinoma ◽  
Concomitant Radiotherapy

Prognostic value of primary tumor volume after concurrent chemoradiation with daily low-dose cisplatin for advanced-stage head and neck carcinoma

Head & Neck ◽  
2008 ◽  
Vol 30 (9) ◽  
pp. 1216-1223 ◽  
Author(s):  
Frank J. P. Hoebers ◽  
Frank A. Pameijer ◽  
Josien de Bois ◽  
Wilma Heemsbergen ◽  
Alfons J. M. Balm ◽  
...  
Keyword(s):  
Head And Neck ◽  
Primary Tumor ◽  
Prognostic Value ◽  
Low Dose ◽  
Tumor Volume ◽  
Head And Neck Carcinoma ◽  
Concurrent Chemoradiation ◽  
Advanced Stage ◽  
Primary Tumor Volume ◽  
Neck Carcinoma

Low-Dose Preoperative Chemoradiation Therapy Compared with Surgery Alone with or Without Postoperative Radiotherapy in Patients with Head and Neck Carcinoma

2011 ◽  
Vol 18 (10) ◽  
pp. 2739-2747 ◽  
Author(s):  
Thomas Mücke ◽  
Mario Konen ◽  
Stefan Wagenpfeil ◽  
Marco R. Kesting ◽  
Klaus-Dietrich Wolff ◽  
...  
Keyword(s):  
Head And Neck ◽  
Low Dose ◽  
Postoperative Radiotherapy ◽  
Head And Neck Carcinoma ◽  
Preoperative Chemoradiation ◽  
Chemoradiation Therapy ◽  
Neck Carcinoma ◽  
Preoperative Chemoradiation Therapy

Early assessment of clinical response to concurrent chemoradiotherapy in head and neck carcinoma using fluoro-2-deoxy-d-glucose positron emission tomography

2008 ◽  
Vol 35 (1) ◽  
pp. 103-108 ◽  
Author(s):  
Choichi Horiuchi ◽  
Takahide Taguchi ◽  
Takafumi Yoshida ◽  
Goshi Nishimura ◽  
Mariko Kawakami ◽  
...  
Keyword(s):  
Positron Emission Tomography ◽  
Head And Neck ◽  
Clinical Response ◽  
Concurrent Chemoradiotherapy ◽  
Head And Neck Carcinoma ◽  
Emission Tomography ◽  
Early Assessment ◽  
Positron Emission ◽  
Neck Carcinoma

Phase I trial of intravenous attenuated vaccinia virus (GL-ONC1) with concurrent chemoradiotherapy (CRT) for locoregionally advanced head and neck carcinoma.

2015 ◽  
Vol 33 (15_suppl) ◽  
pp. 6026-6026 ◽  
Author(s):  
Loren K. Mell ◽  
Yong A. Yu ◽  
Kevin T. Brumund ◽  
Gregory A. Daniels ◽  
Sunil J. Advani ◽  
...  
Keyword(s):  
Phase I ◽  
Vaccinia Virus ◽  
Head And Neck ◽  
Phase I Trial ◽  
Concurrent Chemoradiotherapy ◽  
Head And Neck Carcinoma ◽  
Advanced Head ◽  
Neck Carcinoma

Concurrent chemoradiation with daily low dose cisplatin for advanced stage head and neck carcinoma

2007 ◽  
Vol 85 (1) ◽  
pp. 42-47 ◽  
Author(s):  
Frank J.P. Hoebers ◽  
Wilma Heemsbergen ◽  
Alfons J.M. Balm ◽  
Mathilde van Zanten ◽  
Jan H. Schornagel ◽  
...  
Keyword(s):  
Head And Neck ◽  
Low Dose ◽  
Head And Neck Carcinoma ◽  
Concurrent Chemoradiation ◽  
Advanced Stage ◽  
Neck Carcinoma
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