scholarly journals Required Dose of Sugammadex or Neostigmine for Reversal of Vecuronium‐Induced Shallow Residual Neuromuscular Block at a Train‐of‐Four Ratio of 0.3

2021 ◽  
Author(s):  
Jing He ◽  
Huan He ◽  
Xing Li ◽  
Mei Sun ◽  
Zhihao Lai ◽  
...  
Keyword(s):  
Neuromuscular Block ◽  
Train Of Four ◽  
Residual Neuromuscular Block

Residual Block after Mivacurium with or without Edrophonium Reversal in Adults and Children

1996 ◽  
Vol 84 (2) ◽  
pp. 362-367. ◽  
Author(s):  
David R. Bevan ◽  
Raymond Kahwaji ◽  
John M. Ansermino ◽  
Eleanor Reimer ◽  
Michael F. Smith ◽  
...  
Keyword(s):  
Ulnar Nerve ◽  
Neuromuscular Block ◽  
Saline Group ◽  
Neuromuscular Blocking ◽  
Postanesthesia Care Unit ◽  
Random Allocation ◽  
Train Of Four ◽  
Residual Neuromuscular Block ◽  
Residual Block ◽  
Stimulation Of

Background The rapid recovery from mivacurium- induced neuromuscular block has encouraged omission of its reversal. The purpose of this study was to determine, in children and in adults, whether failure to reverse mivacurium neuromuscular block was associated with residual neuromuscular block on arrival in the postanesthesia care unit. Methods In 50 children, aged 2-12 yr, and 50 adults, aged 20-60 yr, anesthesia was induced and maintained with propofol and fentanyl, and neuromuscular block was achieved by an infusion of mivacurium, to maintain one or two visible responses to train-of-four (TOF) stimulation of the ulnar nerve. At the end of surgery, mivacurium infusion was stopped, and 10 min later, reversal was attempted with saline or 0.5 mg x kg(-1) edrophonium by random allocation. On arrival in the postanesthesia care unit, a blinded observer assessed patients clinically and by stimulation of the ulnar nerve with a Datex electromyogram in the uncalibrated TOF mode. Results Children arrived in the postanesthesia care unit 8.2 +/- 3-4 min after reversal of neuromuscular block and showed no sign of weakness, either clinically or by TOF stimulation. Although TOF ratio was greater in children who had received edrophonium (1.00 +/- 0.05 vs. 0.93 +/- 0.01, P<0.01), TOF was >0.7 in all children. Adults arrived in the postanesthesia care unit 12.9 +/- 5.3 min after reversal of neuromuscular block(P<0.01 vs. children). Six in the saline group demonstrated weakness (two required immediate reversal of neuromuscular block, and TOF was <0.7 in four others), compared with TOF <0.7 in only one of the edrophonium group (P<0.05). Conclusions This study demonstrated that, in adults, failure to reverse mivacurium neuromuscular block was associated with an increased incidence of residual block. Such weakness was not observed in children receiving similar anesthetic and neuromuscular blocking regimens.

Sugammadex and Neostigmine Dose-Finding Study for Reversal of Residual Neuromuscular Block at a Train-of-Four Ratio of 0.2 (SUNDRO20)

2016 ◽  
Vol 60 (6) ◽  
pp. 238-239
Author(s):  
N. Kaufhold ◽  
S. J. Schaller ◽  
C. G. Stäuble ◽  
E. Baumüller ◽  
K. Ulm ◽  
...  
Keyword(s):  
Neuromuscular Block ◽  
Dose Finding ◽  
Finding Study ◽  
Train Of Four ◽  
Dose Finding Study ◽  
Residual Neuromuscular Block

The train-of-four or double-burst ratios cannot reliably exclude residual neuromuscular block in cats

2020 ◽  
Vol 133 ◽  
pp. 131-135
Author(s):  
D.M. Sakai ◽  
C.T. Tseng ◽  
E.A. Militana ◽  
M. Martin-Flores
Keyword(s):  
Neuromuscular Block ◽  
Train Of Four ◽  
Residual Neuromuscular Block

scholarly journals Normalization of acceleromyographic train-of-four ratio by baseline value for detecting residual neuromuscular block

2006 ◽  
Vol 96 (1) ◽  
pp. 44-47 ◽  
Author(s):  
T Suzuki ◽  
N Fukano ◽  
O Kitajima ◽  
S Saeki ◽  
S Ogawa
Keyword(s):  
Neuromuscular Block ◽  
Train Of Four ◽  
Residual Neuromuscular Block

REsidual Neuromuscular Block Prediction Score Versus Train-of-Four Ratio and Respiratory Outcomes: A Retrospective Cohort Study

2021 ◽  
Author(s):  
Maria D. Patrocínio ◽  
Denys Shay ◽  
Maíra I. Rudolph ◽  
Peter Santer ◽  
Stephanie D. Grabitz ◽  
...  
Keyword(s):  
Cohort Study ◽  
Retrospective Cohort Study ◽  
Retrospective Cohort ◽  
Neuromuscular Block ◽  
Prediction Score ◽  
Train Of Four ◽  
Residual Neuromuscular Block ◽  
Respiratory Outcomes

The Duration of Residual Neuromuscular Block After Administration of Neostigmine or Sugammadex at Two Visible Twitches During Train-of-Four Monitoring

2011 ◽  
Vol 112 (1) ◽  
pp. 63-68 ◽  
Author(s):  
Hanna L. Illman ◽  
Päivi Laurila ◽  
Heikki Antila ◽  
Olli A. Meretoja ◽  
Seppo Alahuhta ◽  
...  
Keyword(s):  
Neuromuscular Block ◽  
Train Of Four ◽  
Train Of Four Monitoring ◽  
Residual Neuromuscular Block

The Duration of Residual Neuromuscular Block After Administration of Neostigmine or Sugammadex at Two Visible Twitches During Train-of-Four Monitoring

2011 ◽  
Vol 55 (6) ◽  
pp. 304-305
Author(s):  
Hanna L. Illman ◽  
Päivi Laurila ◽  
Heikki Antila ◽  
Olli A. Meretoja ◽  
Seppo Alahuhta ◽  
...  
Keyword(s):  
Neuromuscular Block ◽  
Train Of Four ◽  
Train Of Four Monitoring ◽  
Residual Neuromuscular Block
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