Endoscopic hand suturing for mucosal defect closure after gastric endoscopic submucosal dissection may reduce the risk of postoperative bleeding in patients receiving antithrombotic therapy

2021 ◽  
Author(s):  
Teppei Akimoto ◽  
Osamu Goto ◽  
Motoki Sasaki ◽  
Mari Mizutani ◽  
Koshiro Tsutsumi ◽  
...  
Keyword(s):  
Endoscopic Submucosal Dissection ◽  
Antithrombotic Therapy ◽  
Postoperative Bleeding ◽  
Defect Closure ◽  
Submucosal Dissection ◽  
Mucosal Defect

scholarly journals Thread-assisted mucosal defect closure using the locking-clip technique after gastric endoscopic submucosal dissection

Endoscopy ◽  
2018 ◽  
Vol 50 (12) ◽  
pp. E342-E343 ◽  
Author(s):  
Tatsuma Nomura ◽  
Akira Kamei ◽  
Shinya Sugimoto ◽  
Tetsuro Harada ◽  
Jun Oyamda
Keyword(s):  
Endoscopic Submucosal Dissection ◽  
Defect Closure ◽  
Submucosal Dissection ◽  
Mucosal Defect

Sa1634 The Postoperative Bleeding Rate and Its Risk Factors in Patients on Antithrombotic Therapy Who Undergo Gastric Endoscopic Submucosal Dissection

2014 ◽  
Vol 79 (5) ◽  
pp. AB282
Author(s):  
Toshihisa Takeuchi ◽  
Ota Kazuhiro ◽  
Satoshi Harada ◽  
Shoko Edogawa ◽  
Yuichi Kojima ◽  
...  
Keyword(s):  
Risk Factors ◽  
Endoscopic Submucosal Dissection ◽  
Antithrombotic Therapy ◽  
Postoperative Bleeding ◽  
Bleeding Rate ◽  
Submucosal Dissection

877 MUCOSAL DEFECT CLOSURE BY ENDOSCOPIC HAND-SUTURING MAY REDUCE BLEEDING RISK AFTER GASTRIC ENDOSCOPIC SUBMUCOSAL DISSECTION: A MULTICENTER PILOT STUDY

2020 ◽  
Vol 91 (6) ◽  
pp. AB71-AB72
Author(s):  
Osamu Goto ◽  
Tsuneo Oyama ◽  
Hiroyuki Ono ◽  
Akiko Takahashi ◽  
Mitsuhiro Fujishiro ◽  
...  
Keyword(s):  
Pilot Study ◽  
Endoscopic Submucosal Dissection ◽  
Bleeding Risk ◽  
Defect Closure ◽  
Submucosal Dissection ◽  
Mucosal Defect

scholarly journals Postoperative bleeding after gastric endoscopic submucosal dissection in patients receiving antithrombotic therapy

2016 ◽  
Vol 20 (1) ◽  
pp. 207-214 ◽  
Author(s):  
Tsukasa Furuhata ◽  
Mitsuru Kaise ◽  
Shu Hoteya ◽  
Toshiro Iizuka ◽  
Akihiro Yamada ◽  
...  
Keyword(s):  
Endoscopic Submucosal Dissection ◽  
Antithrombotic Therapy ◽  
Postoperative Bleeding ◽  
Submucosal Dissection

Efficacy of an over-the-scope clip for preventing adverse events after duodenal endoscopic submucosal dissection: a prospective interventional study

Endoscopy ◽  
2018 ◽  
Vol 50 (05) ◽  
pp. 487-496 ◽  
Author(s):  
Tomoaki Tashima ◽  
Ken Ohata ◽  
Eiji Sakai ◽  
Yoshitsugu Misumi ◽  
Maiko Takita ◽  
...  
Keyword(s):  
Adverse Events ◽  
Endoscopic Submucosal Dissection ◽  
R0 Resection ◽  
Defect Closure ◽  
Submucosal Dissection ◽  
Mucosal Defect ◽  
Over The Scope Clip ◽  
Delayed Perforation ◽  
The Mean ◽  
Severe Adverse Events

Abstract Background Duodenal endoscopic submucosal dissection (ESD) remains technically challenging, with a high risk of severe adverse events. Because exposure of the duodenal post-ESD mucosal defect to pancreatic juice and bile acid reportedly induces delayed perforation and bleeding, we examined whether defect closure using an over-the-scope clip (OTSC) system was useful for preventing postoperative adverse events. Methods From April 2016 to February 2017, a total of 50 consecutive patients with superficial non-ampullary duodenal epithelial tumors (SNADETs) larger than 10 mm, with no more than semi-circumferential spread, were prospectively enrolled in this study. All of the lesions were treated by experienced ESD operators and the post-ESD mucosal defect was closed using OTSCs. Results All of the SNADETs were completely removed by ESD, with an R0 resection rate of 88.0 %. The mean procedure and closure times were 67.3 ± 58.8 minutes and 9.8 ± 7.2 minutes, respectively. Although complete defect closure was achieved in 94.0 % of the patients (47/50), two patients required surgical conversion. Delayed perforation occurred in only one patient (2.1 %), who did not have successful closure of the defect, as misplacement of the OTSC exposed the muscle layer. Meanwhile, delayed bleeding occurred in three patients (6.3 %); however, the bleeding was easily controlled using endoscopic coagulation. The mean duration of postoperative hospitalization was 5.5 ± 7.2 days. Conclusions Prophylactic defect closure using OTSCs may be effective in reducing severe adverse events after duodenal ESD.

Effect of Antithrombotic Therapy and Long Endoscopic Submucosal Dissection Procedure Time on Early and Delayed Postoperative Bleeding

Digestion ◽  
2017 ◽  
Vol 96 (1) ◽  
pp. 21-28 ◽  
Author(s):  
Nobue Ueki ◽  
Seiji Futagami ◽  
Teppei Akimoto ◽  
Yuta Maruki ◽  
Hiroshi Yamawaki ◽  
...  
Keyword(s):  
Endoscopic Submucosal Dissection ◽  
Antithrombotic Therapy ◽  
Postoperative Bleeding ◽  
Procedure Time ◽  
Submucosal Dissection

scholarly journals Mucosal defect closure after duodenal endoscopic submucosal dissection using the reopenable‐clip over the line method

JGH Open ◽  
2021 ◽  
Author(s):  
Tatsuma Nomura ◽  
Shinya Sugimoto ◽  
Nobuyuki Tsuda ◽  
Ryutaro Matsushima ◽  
Jun Oyamada ◽  
...  
Keyword(s):  
Endoscopic Submucosal Dissection ◽  
Defect Closure ◽  
Line Method ◽  
Submucosal Dissection ◽  
Mucosal Defect
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