scholarly journals Model‐based characterization of the relationship between dapagliflozin systemic exposure and HbA1c response in patients with type 1 diabetes mellitus

2019 ◽  
Vol 21 (6) ◽  
pp. 1381-1387
Author(s):  
Joanna Parkinson ◽  
Weifeng Tang ◽  
Magnus Åstrand ◽  
Johanna Melin ◽  
Ella Ekholm ◽  
...  
2020 ◽  
Vol 34 (6) ◽  
pp. 8459-8474
Author(s):  
Yann‐Jinn Lee ◽  
Wei‐Hsin Ting ◽  
Yi‐Wen Yang ◽  
Cheng‐Jui Lin ◽  
Yu‐Ting Hsieh ◽  
...  

1999 ◽  
Vol 283 (1-2) ◽  
pp. 119-128 ◽  
Author(s):  
Iain R. Brown ◽  
Alasdair M. McBain ◽  
John Chalmers ◽  
Ian W. Campbell ◽  
Ewan R. Brown ◽  
...  

2017 ◽  
Vol 40 (10) ◽  
pp. 1107-1113 ◽  
Author(s):  
F. Bertuzzi ◽  
E. Meneghini ◽  
E. Bruschi ◽  
L. Luzi ◽  
M. Nichelatti ◽  
...  

Author(s):  
Pedro Romero-Aroca ◽  
Juan Fernandez-Ballart ◽  
Nuria Soler ◽  
Marc Baget-Bernaldiz ◽  
Isabel Mendez-Mari

2019 ◽  
Vol 7 ◽  
pp. 2050313X1982773 ◽  
Author(s):  
Noor S Bawahab ◽  
Osama Y Safdar ◽  
Sarah A Nagadi ◽  
Asalh T Saeedi ◽  
Raghad W Mohammed Hussain

Occurrence of early nephrotic syndrome in type 1 diabetes mellitus patients is extremely rare. Herein, we report the case of a 12-year-old boy who presented to our pediatric nephrology clinic with generalized edema. He had been diagnosed with type 1 diabetes mellitus at age 9 and had been treated with regular insulin. Examinations revealed normal kidney function, hypoalbuminemia, proteinuria (4+), hyperlipidemia, and low protein-to-creatinine ratio. The patient was diagnosed with idiopathic nephrotic syndrome and was empirically administered prednisolone for 12 weeks. Subsequently, prednisolone was tapered over 10–12 weeks. The patient showed good response to treatment. In conclusion, co-existence of nephrotic syndrome and type 1 diabetes mellitus may suggest an immunological basis; therefore, further studies are needed to investigate the relationship between these two conditions.


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