Panax notoginseng saponin attenuates the hypoxic–ischaemic injury in neonatal rats by regulating the expression of neurotrophin factors

2021 ◽  
Vol 54 (6) ◽  
pp. 6304-6321
Author(s):  
Jin Huang ◽  
Ya‐Xin Tan ◽  
Lu‐Lu Xue ◽  
Ruo‐Lan Du ◽  
Jun‐Jie Chen ◽  
...  

Author(s):  
K.A. Carson ◽  
C.B. Nemeroff ◽  
M.S. Rone ◽  
J.S. Kizer ◽  
J.S. Hanker

Biochemical, physiological, pharmacological, and more recently enzyme histo- chemical data have indicated that cholinergic circuits exist in the hypothalamus. Ultrastructural correlates of these pathways such as acetylcholinesterase (AchE) positive neurons in the arcuate nucleus (ARC) and stained terminals in the median eminence (ME) have yet to be described. Initial studies in our laboratories utilizing chemical lesioning and microdissection techniques coupled with microchemical and light microscopic enzyme histo- chemical studies suggested the existence of cholinergic neurons in the ARC which project to the ME (1). Furthermore, in adult male rats with Halasz deafferentations (hypothalamic islands composed primarily of the isolated ARC and the ME) choline acetyltransferase (ChAc) activity, a good marker for cholinergic neurons, was not significantly reduced in the ME and was only somewhat reduced in the ARC (2). Treatment of neonatal rats with high doses of monosodium 1-glutamate (MSG) results in a lesion largely restricted to the neurons of the ARC.



2010 ◽  
Vol 34 (8) ◽  
pp. S28-S28
Author(s):  
Juan Liu ◽  
Lianxiang Zhang ◽  
Yujun Wen ◽  
Yiwei Zhang ◽  
Toshihito Suzuki




2019 ◽  
Vol 47 (1) ◽  
pp. 1-14
Author(s):  
C. Ye ◽  
H Y. Fang ◽  
H J. Liu ◽  
M. Yang ◽  
S S. Zhu


2018 ◽  
Vol 44 (2) ◽  
pp. 145-158 ◽  
Author(s):  
H.J. Liu ◽  
X.Y. Yang ◽  
Z.Q. Miao ◽  
S.D. Li ◽  
Y.H. Chen ◽  
...  


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