The effects of flumazenil on ventilatory and recovery characteristics in horses following midazolam‐ketamine induction and isoflurane anaesthesia

2020 ◽  
Author(s):  
Hope Douglas ◽  
Klaus Hopster ◽  
Michelle Cerullo ◽  
Charlotte Hopster‐Iversen ◽  
Darko Stefanovski ◽  
...  

1987 ◽  
Vol 31 (3) ◽  
pp. 233-238 ◽  
Author(s):  
G. P. Johannesson ◽  
S. G. E. Lindahl ◽  
G. H. Sigurdsson ◽  
N. E. Nordén


2000 ◽  
Vol 27 (1) ◽  
pp. 57-58
Author(s):  
KR Mama ◽  
AE Wagner ◽  
EP Steffey






1993 ◽  
Vol 71 (2) ◽  
pp. 222-226 ◽  
Author(s):  
R.A. COOPER ◽  
V.R. MADDINENI ◽  
R.K. MIRAKHUR ◽  
J.M.K.H. WIERDA ◽  
M. BRADY ◽  
...  


1990 ◽  
Vol 37 (7) ◽  
pp. 739-742 ◽  
Author(s):  
Pamela R. McCulloch ◽  
Brian Milne


2018 ◽  
Vol 53 (2) ◽  
pp. 190-201 ◽  
Author(s):  
Marlene Resch ◽  
Tania Neels ◽  
Alexander Tichy ◽  
Rupert Palme ◽  
Thomas Rülicke

Intravenous (IV) administration in mice is predominantly performed via the lateral tail veins. The technique requires adequate training before it can be used safely and routinely. A novel anaesthesia induction chamber has been developed to simplify the treatment and to facilitate IV injection in mice, particularly for untrained personnel. We have assessed the benefits of the chamber in refining IV injection in isoflurane-anaesthetized mice in direct comparison with the common restrainer method on conscious animals. The body weight, nesting behaviour and concentrations of faecal corticosterone metabolites were taken as indicative of distress induced by the various procedures. The results suggest that both methods of tail-vein injection induce similar levels of momentary stress in the animals, revealed by a short-term increase in the levels of stress hormone metabolites in faeces. A temporary reduction of body weight was observed after IV injection under isoflurane anaesthesia but not for conscious mice injected in the common restrainer. We conclude that the severity of tail-vein injection in mice is ‘mild’ for both methods. There was no evidence that refining the procedure by using isoflurane anaesthesia in the induction chamber was associated with any benefit.



2004 ◽  
Vol 16 (1) ◽  
pp. 65-69
Author(s):  
Isil Ozkocak ◽  
Murat Akcay ◽  
Yasar Pala ◽  
Bayazit Dikmen ◽  
Nermin Gogus




Author(s):  
G.F. Stegmann

The cardiovascular effects of non-abdominal and abdominal surgery during isoflurane anaesthesia (A-group) or isoflurane anaesthesia supplemented with either epidural ropivacaine (AR-group; 0.75 % solution, 0.2 mℓ/kg) or morphine (AM-group; 0.1 mg/kg diluted in saline to 0.2mℓ/kg) were evaluated in 28 healthy pigs with a mean body weight of 30.3 kg SD ± 4.1 during surgical devascularisation of the liver. Anaesthesia was induced with the intramuscular injection of midazolam (0.3 mg/kg) and ketamine (10 mg/kg). Anaesthesia was deepened with intravenous propofol to enable tracheal intubation and maintained with isoflurane on a circle rebreathing circuit. The vaporiser was set at 2.5% for the A-group and 1.5% for the AR- and AM-groups. Differences between treatment groups were not statistically significant (P>0.05) for any of the variables. Differences between AM- and AR-groups were marginally significant heart rate (HR) (P = 0.06) and mean arterial blood pressure (MAP) (P = 0.08). Within treatment groups, differences for the A-group were statistically significant (P<0.05) between non-abdominal and abdominal surgery for HR, systolic blood pressure, diastolic blood pressure (DIA) and MAP. Within the AM-group differences were statistically significant (P < 0.05) for DIA and MAP, and within the AR group differences for all variables were not statistically significant (P > 0.05). It was concluded that in isoflurane-anaesthetised pigs, the epidural administration of ropivacaine decreased heart rate and improved arterial blood pressure during surgery.



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