scholarly journals Structural and functional importance of local and global conformational fluctuations in the RNase A superfamily

FEBS Journal ◽  
2013 ◽  
Vol 280 (22) ◽  
pp. 5596-5607 ◽  
Author(s):  
Donald Gagné ◽  
Nicolas Doucet



2001 ◽  
Vol 53 (1) ◽  
pp. 31-38 ◽  
Author(s):  
Helene F. Rosenberg ◽  
Jianzhi Zhang ◽  
You-Di Liao ◽  
Kimberly D. Dyer


2003 ◽  
Vol 31 (2) ◽  
pp. 602-607 ◽  
Author(s):  
J. Zhang




2010 ◽  
Vol 433 (2) ◽  
pp. 345-355 ◽  
Author(s):  
Elio Pizzo ◽  
Antonello Merlino ◽  
Mimmo Turano ◽  
Irene Russo Krauss ◽  
Francesca Coscia ◽  
...  

Recently, extracellular RNases of the RNase A superfamily, with the characteristic CKxxNTF sequence signature, have been identified in fish. This has led to the recognition that these RNases are present in the whole vertebrate subphylum. In fact, they comprise the only enzyme family unique to vertebrates. Four RNases from zebrafish (Danio rerio) have been previously reported and have a very low RNase activity; some of these are endowed, like human angiogenin, with powerful angiogenic and bactericidal activities. In the present paper, we report the three-dimensional structure, the thermodynamic behaviour and the biological properties of a novel zebrafish RNase, ZF-RNase-5. The investigation of its structural and functional properties, extended to all other subfamily members, provides an inclusive description of the whole zebrafish RNase subfamily.





2006 ◽  
Vol 10 (4) ◽  
pp. 585-597 ◽  
Author(s):  
Kimberly D. Dyer ◽  
Helene F. Rosenberg


2009 ◽  
Vol 86 (5) ◽  
pp. 1217-1226 ◽  
Author(s):  
Marianna Kulka ◽  
Nobuyuki Fukuishi ◽  
Dean D. Metcalfe


2019 ◽  
Vol 10 ◽  
Author(s):  
Guillem Prats-Ejarque ◽  
Lu Lu ◽  
Vivian A. Salazar ◽  
Mohammed Moussaoui ◽  
Ester Boix


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