Response to the correspondence: a randomized, open, controlled trial of tretinoin 0.05% cream vs. low‐dose oral isotretinoin for the treatment of field cancerization

2019 ◽  
Vol 58 (10) ◽  
Author(s):  
Mayra Ianhez ◽  
Sebastião A. Pinto ◽  
Ediléia Bagatin ◽  
Helio A. Miot

2019 ◽  
Vol 58 (3) ◽  
pp. 365-373 ◽  
Author(s):  
Mayra Ianhez ◽  
Sebastião A. Pinto ◽  
Helio A. Miot ◽  
Ediléia Bagatin


2003 ◽  
Vol 56 (6) ◽  
pp. 683-690 ◽  
Author(s):  
Arabelle Pfrunder ◽  
Monika Schiesser ◽  
Simone Gerber ◽  
Manuel Haschke ◽  
Johannes Bitzer ◽  
...  


2019 ◽  
Vol 36 (6) ◽  
pp. 980-981 ◽  
Author(s):  
Nuria Rodriguez‐Garijo ◽  
Elena Querol‐Cisneros ◽  
Alejandra Tomas‐Velazquez ◽  
Angela Estenaga ◽  
Ester Moreno‐Artero ◽  
...  
Keyword(s):  
Low Dose ◽  


Author(s):  
Savithri D. R. ◽  
Suvarna R. ◽  
Prashanthi Chennupalli ◽  
Akshatha S.

Background: Induction of labour is a therapeutic option when the benefits of delivery outweigh risks of continuing pregnancy. There are several agents for induction of labour to achieve better outcome of labour. Acceptable methods for induction are oxytocin infusion, dinoprostone gel, misoprostol and mechanical cervical dilators. Prostaglandins are the preferred choice in unripened cervix. To study the neonatal outcome in induction of labour with low dose oral misoprostol compared with intracervical dinoprostone gel and also to assess occurrence of meconium staining liquor.Methods: One hundred women with single live fetus, term gestation, cephalic presentation, reactive fetal heart pattern and Bishops score <6 were included in the study. They were randomized to receive either 6 doses of 25ug oral misoprostol every 3rd hourly or 0.5ug intracervical dinoprostone every 6th hourly for a maximum of 3 doses. Oxytocin was administered. Fetal outcome was assessed in terms of APGAR score, meconium staining and need for NICU.Results: Meconium stained amniotic fluid was high in misoprostol group (16%) compared to dinoprostone group (8%). NICU admissions were seen in 7 neonates in both groups.Conclusions: Low dose oral misoprostol is a safe method of labour induction. APGAR and NICU admission rates were comparable in both groups. Meconium staining was more in misoprostol group compared to dinoprostone group.



Author(s):  
Rashmi Jindal ◽  
Samarjit Roy ◽  
Akanksha Jain

<p class="abstract"><strong>Background:</strong> Oral isotretinoin and azithromycin are two important drugs used in management of acne. Their mode of action is different and thus theoretically the combination of these two should have a synergistic effect.</p><p class="abstract"><strong>Methods:</strong> In this randomized comparative trial 100 patients were randomized into two groups. One received oral isotretinoin (0.3 mg/kg/day) alone and the other group received pulsed azithromycin (500 mg/day for three days in a week for 8 weeks) in addition to oral isotretinoin. Improvement in acne was noted as percentage improvement in mean acne score.<strong></strong></p><p class="abstract"><strong>Results:</strong> No statistically significant difference was noted in the improvement in mean acne score of both the groups.</p><p><strong>Conclusions:</strong> Addition of pulsed azithromycin to low dose oral isotretinoin does not offer a better treatment outcome in patients of moderate to severe acne. </p>



Author(s):  
Federica FILIPPI ◽  
Laura VOLLONO ◽  
Bianca M. PIRACCINI ◽  
Cosimo MISCIALI ◽  
Federico TARTARI ◽  
...  
Keyword(s):  
Low Dose ◽  




BMJ ◽  
1985 ◽  
Vol 291 (6505) ◽  
pp. 1305-1308 ◽  
Author(s):  
E Imbasciati ◽  
R Gusmano ◽  
A Edefonti ◽  
P Zucchelli ◽  
C Pozzi ◽  
...  


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