Pemphigoid lichen planus consequential to vildagliptin: a rare variant of bullous pemphigoid?

2019 ◽  
Vol 59 (1) ◽  
Author(s):  
Francisco J. Navarro‐Triviño ◽  
Jairo Lopez Gomez ◽  
Francisco M. R. Pleguezuelos ◽  
Ricardo Ruiz‐Villaverde
2012 ◽  
Vol 4 (1) ◽  
pp. 35-37
Author(s):  
I Bhuiyan ◽  
MS Hossain ◽  
MSA Khan ◽  
M Alam ◽  
MA Haque

Lichen planus pemphigoides describe a rare subset of patients who usually have typical lichen planus then develop blistering on their lichen planus lesions and in normal skin. Less commonly the blistering antedates the lichen planus. They clinically appear to be a combination of lichen planus and bullous pemphigoid. Oral disease may occur and resemble either lichen planus or bullous pemphigoid. Lichen planus pemphigoides has been triggered by medication & PUVA. Pruritus may be severe and lesions may evolve to resemble pemphigoid nodularis. Histopathologically lichen planus lesions show lichen planus and bullous lesion shows the features of bullous pemphigoid. DIF is positive in a linear pattern with IgG and C3 along the basement membrane zone, at the roof of saline split skin. The antigen targeted by the autoantibody in Lichen planus pemphigoides is located in the same region as the bullous pemphigoid antigen (at the basal hemidesmosomes). Lichen planus pemphigoides tends to follow a benign and chronic course, even when compared to bullous pemphigoid. We diagnosed a case of Lichen planus pemphigoides on the basis of history, clinical examination, histopathology & DIF. The patient was treated with systemic & topical steroid, Dapsone. After 2 month of treatment steroid was withdrawn, but Dapsone continue with no relapse.To our knowledge this is the first diagnosed and treated case in this hospital. DOI: http://dx.doi.org/10.3329/jssmc.v4i1.12002 J Shaheed Suhrawardy Med Coll, 2012;4(1):35-37


2017 ◽  
Vol 137 (10) ◽  
pp. S275
Author(s):  
F. Solimani ◽  
A. Schmidt ◽  
R. Eming ◽  
M. Hertl ◽  
T. Schmidt

2015 ◽  
Vol 19 (2) ◽  
pp. 153-155 ◽  
Author(s):  
Waleed Al-Salhi ◽  
Ru'aa Alharithy

Background Pemphigoid nodularis is a rare clinical variant of bullous pemphigoid characterized by overlapping clinical features of both prurigo nodularis lesions and bullous pemphigoid blisters. The condition appears to be more common in females and is often resistant to treatment. Objective To raise awareness of this rare variant of bullous pemphigoid. Methods Case report. Results and Conclusion Dermatologists should include this variant in differential diagnosis of prurigo nodularis because early recognition can lead to an effective treatment for the prurigo component.


2021 ◽  
Vol 13 (3) ◽  
pp. 283-286
Author(s):  
A.S. Peeters ◽  
N Dhont ◽  
H Stals

In this case report we present a young patient with localised childhood vulvar pemphigoid. It is a rare variant of bullous pemphigoid with mostly a favourable prognosis and prompt response to potent topical corticosteroids. She presented with relapsing vulvar pain and lesions. Our case enlightens the recognition of this unusual subtype and the importance of performing a cutaneous biopsy.


2020 ◽  
Vol 14 (1) ◽  
pp. 23-25
Author(s):  
Tuğba Kevser Uzunçakmak ◽  
Ayşe Serap Karadağ ◽  
Necmettin Akdeniz ◽  
Emin Özlü ◽  
Ebru Itır Zemheri

Author(s):  
N. Padmapriya ◽  
K. Karthikeyan

<p class="abstract">Lichen planus (LP) is a papulosquamous disorder with both cutaneous and mucosal manifestation. Linear lichen planus is rare variant of lichen planus which occurs in the extremities. Oral lichen planus is another variant of lichen planus. Coexistence of linear lichen planus with oral lichen planus is rare and only one case has been reported before this case. A 35 year old female presented with hyperpigmented linear lesion in the leg and whitish plaques in the oral cavity. Biopsy of the skin lesions showed features of lichen planus. The patient was started on topical steroids and oral hydroxychloroquine. Patient responded to treatment.</p>


2008 ◽  
Vol 12 (1) ◽  
pp. 35-37
Author(s):  
Melody J. Cheung-Lee ◽  
Jaggi Rao

Background: Lichen planus (LP) is a condition with many clinical variants that can be quite varied in their presentation. Objective: We report a case of a 60-year-old woman who presented with a very unusual palmoplantar eruption characterized by violaceous pustule-like papules that was subsequently diagnosed as LP. Methods: The above case is reported, along with biopsy results. The patient was subsequently treated with a combination of topical corticosteroids and oral acitretin, and her clinical course was followed. Results: The eruption responded dramatically to our combination treatment and resolved by the 2-month follow-up. Conclusion: Palmoplantar LP is a rare variant of LP that bears little resemblance to its classic LP. This condition responds well to a combination of potent topical corticosteroids and oral acitretin.


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