scholarly journals Comparative genetics of the major histocompatibility complex in humans and nonhuman primates

2020 ◽  
Vol 47 (3) ◽  
pp. 243-260
Author(s):  
Corrine M.C. Heijmans ◽  
Natasja G. Groot ◽  
Ronald E. Bontrop
Keyword(s):  
Major Histocompatibility Complex ◽  
Nonhuman Primates ◽  
Major Histocompatibility ◽  
Comparative Genetics ◽  
Histocompatibility Complex

scholarly journals Major Histocompatibility complex-DMB allelic diversity in old and new world nonhuman primates: Intraspecies pattern of evolution

2015 ◽  
Vol 1 (8) ◽  
pp. 25 ◽  
Author(s):  
Maria José Recio ◽  
Ester Muniz ◽  
Jose Palacio-Grüber ◽  
Jorge Martinez-Laso ◽  
Eduardo Gomez-Casado ◽  
...  
Keyword(s):  
Major Histocompatibility Complex ◽  
New World ◽  
Nonhuman Primates ◽  
Allelic Diversity ◽  
Major Histocompatibility ◽  
Histocompatibility Complex

Major histocompatibility complex class I molecules of nonhuman primates

1988 ◽  
Vol 18 (9) ◽  
pp. 1425-1432 ◽  
Author(s):  
David I. Watkins ◽  
Mari Kannagi ◽  
Marc E. Stone ◽  
Norman L. Letvin
Keyword(s):  
Major Histocompatibility Complex ◽  
Major Histocompatibility Complex Class ◽  
Nonhuman Primates ◽  
Class I ◽  
Complex Class ◽  
Major Histocompatibility ◽  
Histocompatibility Complex

Major Histocompatibility Complex Class I-related Chains A and B (MIC A/B): A Role in the Pathogenesis of Non-alcoholic Steatohepatitis

2009 ◽  
Vol 47 (01) ◽  
Author(s):  
A Kahraman ◽  
S Menziletoglu Yildiz ◽  
M Schlattjan ◽  
A Kilicarslan ◽  
CD Fingas ◽  
...  
Keyword(s):  
Major Histocompatibility Complex ◽  
Major Histocompatibility Complex Class ◽  
Class I ◽  
Complex Class ◽  
Major Histocompatibility ◽  
Alcoholic Steatohepatitis ◽  
Histocompatibility Complex

Relationship of Major Histocompatibility Complex Class II Genes to Inhibitor Antibody Formation in Hemophilia A

1990 ◽  
Vol 64 (04) ◽  
pp. 564-568 ◽  
Author(s):  
Lloyd E Lippert ◽  
Lyman Mc A Fisher ◽  
Lawrence B Schook
Keyword(s):  
Major Histocompatibility Complex ◽  
Factor Viii ◽  
Antibody Formation ◽  
Rflp Analysis ◽  
Class Ii ◽  
Major Histocompatibility ◽  
Odds Ratios ◽  
Inhibitory Antibody ◽  
Histocompatibility Complex ◽  
Hla Dr

SummaryApproximately 14% of transfused hemophiliacs develop an anti-factor VIII inhibitory antibody which specifically neutralizes factor VIII procoagulant activity. In this study an association of the major histocompatibility complex (MHC) with inhibitor antibody formation was evaluated by restriction fragment length polymorphism (RFLP) analysis using BamHI, EcoRI, HindII, PstI, PvuII and TaqI digested genomic DNA probed with DP beta, DQ alpha, DQ beta and DR beta class II MHC gene probes. The RFLP patterns for 16 non-inhibitor and 11 inhibitor hemophiliac patients were analyzed. These 24 enzyme:probe combinations generated 231 fragments. Fifteen (15) fragments associated with the inhibitor phenotype; odds ratios ranged from 5.1 to 45 and lower bounds of 95% confidence intervals were > 1.000 for all 15 fragments. Five (5) fragments associated with non-inhibitors, with odds ratios ranging from 6.4 to 51.7. This report establishes a MHC related genetic basis for the inhibitor phenotype. No statistically significant differences in the distribution of serologically defined HLA-DR phenotypes were observed between the inhibitor and non-inhibitor groups.

Association of susceptibility to spontaneous diabetes in rat with genes of major histocompatibility complex

Diabetes ◽  
1988 ◽  
Vol 37 (10) ◽  
pp. 1438-1443 ◽  
Author(s):  
E. Colle ◽  
S. J. Ono ◽  
A. Fuks ◽  
R. D. Guttmann ◽  
T. A. Seemayer
Keyword(s):  
Major Histocompatibility Complex ◽  
Spontaneous Diabetes ◽  
Major Histocompatibility ◽  
Histocompatibility Complex
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