HOW OFTEN IS CANCER OF THE STOMACH MISDIAGNOSED AS PEPTIC ULCER?

The importance of the truth in science is emphasized and the difficulty of finding the truth by searching medical literature is pointed out. Two pathological problems are considered as illustrations. The great variation of opinion as to the frequency of ulcer-cancer of the stomach is noted and the lack of definite histological criteria for its diagnosis is suggested as the cause of this variation. Four points in the diagnosis of pre-existing peptic ulcer are mentioned and the importance of fusion between the muscularis mucosæ and muscularis at the edge of the ulcer is insisted upon. The risk of mistaking deep epithelial heterotopia for carcinoma is illustrated. The problem of the origin of Grawitz tumours of the kidney is next considered and the literature briefly reviewed. The rarity of carcinoma of the suprarenal compared with Grawitz tumours is indicated by an examination of 5,201 autopsies at St. Mary's Hospital. The variation in sex incidence of the two tumours is also commented upon. The results of an analysis of 387 small nodules found in the kidneys in 1,172 necropsies are given. Adenomata were found in 7.2% and accessory suprarenals in 2.6%. An example of a transition between an adenoma and a Grawitz tumour is illustrated. Stress is laid on the essential papillary structure of the Grawitz tumour and it is suggested that the renal theory of its origin is more likely to be true.

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Antichelicobacter therapy in the context of increasing bacterial resistance

Medicine of Ukraine ◽

10.37987/1997-9894.2021.1(247).226316 ◽

2021 ◽

pp. 24-27

Author(s):

Ya. V. Korost ◽

N. M. Gorobets

Keyword(s):

Helicobacter Pylori ◽

Peptic Ulcer ◽

Gastrointestinal Tract ◽

Bacterial Resistance ◽

Gastric Lymphoma ◽

Pathological Process ◽

Peptic Ulcers ◽

Cancer Of The Stomach ◽

Main Components ◽

Further Development

A modern strategy for the treatment of diseases associated with Helicobacter pylori is the mandatory inclusion in the scheme of treatment of antibiotics, as well as considering the level of bacterial resistance to the main components of therapy. In Ukraine, Helicobacter pylori infection in some areas can reach about 80%, so the prevalence of peptic ulcer, atrophic gastritis and other diseases of the gastrointestinal tract is extremely high in all sections of the population. Topical for our country is the use of standard triple antyhelicobacter therapy, which includes: proton pump inhibitor in combination with clarithromycin + amoxicillin. Such therapy lasting 10 or 14 days allows to completely free the gastrointestinal tract from Helicobacter pylori, and to prevent the further development of pathological process on the mucous membrane. This tactic can successfully prevent the growth of incidence of gastric lymphoma, cancer of the stomach, as well as reduce the likelihood of complications in peptic ulcers.

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PEPTIC ULCER AND CANCER OF THE STOMACH

Journal of the American Medical Association ◽

10.1001/jama.1929.02700480003002 ◽

1929 ◽

Vol 92 (22) ◽

pp. 1813

Author(s):

J. SHELTON HORSLEY

Keyword(s):

Peptic Ulcer ◽

Cancer Of The Stomach

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To X-ray diagnostics of malignant neoplasms in patients with operated stomach

Kazan medical journal ◽

10.17816/kazmj83340 ◽

2021 ◽

Vol 43 (2) ◽

pp. 28-31

Author(s):

M. I. Goldstein

Keyword(s):

Peptic Ulcer ◽

Surgical Intervention ◽

Malignant Neoplasms ◽

Primary Cancer ◽

X Ray ◽

Cancer Of The Stomach ◽

Recurrent Tumors ◽

Operated Stomach

The decisive method for the treatment of malignant neoplasms of the stomach is surgical intervention. The successes achieved in this direction are limited mainly to surgery for primary cancer of the stomach. Patients with recurrent tumors in the stomach stump, as well as with secondary malignant neoplasms in this area after surgery for peptic ulcer, polyps and other diseases, were considered doomed and hopeless until recently.

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