The Long-term Prognosis of Acute Glomerulonephritis: A Follow-up Study

2009 ◽  
Vol 181 (1) ◽  
pp. 13-19 ◽  
Author(s):  
K. J. Berg ◽  
S. Ritland
Keyword(s):  
Acute Glomerulonephritis ◽  
Follow Up Study ◽  
Long Term Prognosis

A long-term follow-up study of 18 patients with sporadic hemiplegic migraine

Cephalalgia ◽  
2010 ◽  
Vol 31 (2) ◽  
pp. 199-205 ◽  
Author(s):  
Anine H Stam ◽  
Mark A Louter ◽  
Joost Haan ◽  
Boukje de Vries ◽  
Arn MJM van den Maagdenberg ◽  
...  
Keyword(s):  
Familial Hemiplegic Migraine ◽  
Initial Diagnosis ◽  
Hemiplegic Migraine ◽  
Optimal Care ◽  
Follow Up Study ◽  
Long Term Follow Up ◽  
Atp1a2 Gene ◽  
Long Term Prognosis

Objective: Our objective was to study the long-term prognosis of sporadic hemiplegic migraine (SHM). Methods: We performed a longitudinal follow-up study in 18 patients who were diagnosed with SHM between 1993 and 1996. Follow-up time between the first and second survey ranged from nine to 14 years. These patients were included as part of a genetic study in which we systematically analysed the role of the three known familial hemiplegic migraine (FHM) genes. Results: In 12 out of 18 patients the clinical diagnosis was unchanged. In two of the six remaining patients the attacks were no longer associated with hemiplegia; one of them had an ATP1A2 gene mutation (E120A). In the four other patients, the diagnosis changed into FHM, because a family member had developed hemiplegic migraine since the initial diagnosis was made. In two of the four patients a mutation was demonstrated ( CACNA1A [R583Q] and ATP1A2 [R834X]). Conclusion: This study shows that the diagnosis of SHM changes into FHM in a considerable percentage of patients (22% [4 of 18]), almost a decade after the initial diagnosis. This indicates that a careful follow-up of SHM patients and their families is advisable for optimal care and counseling. Diagnostic screening of FHM genes in SHM patients can be of value. Our genetic and clinical follow-up studies reinforce the evidence that FHM and SHM are part of the same spectrum of migraine.

scholarly journals Characterisation of long-term cancer survivors and application of statistical cure models: a protocol for an observational follow-up study in patients with colorectal cancer

2020 ◽  
Vol 20 (1) ◽  
Author(s):  
Sonia Pértega-Díaz ◽  
Vanesa Balboa-Barreiro ◽  
Rocío Seijo-Bestilleiro ◽  
Cristina González-Martín ◽  
Remedios Pardeiro-Pértega ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Term Survival ◽  
Long Term Survival ◽  
Follow Up Study ◽  
Cure Models ◽  
Long Term Prognosis ◽  
Clinical Records ◽  
Long Term Survivors

Abstract Background Improved colorectal cancer (CRC) survival rates have been reported over the last years, with more than half of these patients surviving more than 5 years after the initial diagnosis. Better understanding these so-called long-term survivors could be very useful to further improve their prognosis as well as to detect other problems that may cause a significant deterioration in their health-related quality of life (HRQoL). Cure models provide novel statistical tools to better estimate the long-term survival rate for cancer and to identify characteristics that are differentially associated with a short or long-term prognosis. The aim of this study will be to investigate the long-term prognosis of CRC patients, characterise long-term CRC survivors and their HRQoL, and demonstrate the utility of statistical cure models to analyse survival and other associated factors in these patients. Methods This is a single-centre, ambispective, observational follow-up study in a cohort of n = 1945 patients with CRC diagnosed between 2006 and 2013. A HRQoL sub-study will be performed in the survivors of a subset of n = 485 CRC patients for which baseline HRQoL data from the time of their diagnosis is already available. Information obtained from interviews and the clinical records for each patient in the cohort is already available in a computerised database from previous studies. This data includes sociodemographic characteristics, family history of cancer, comorbidities, perceived symptoms, tumour characteristics at diagnosis, type of treatment, and diagnosis and treatment delay intervals. For the follow-up, information regarding local recurrences, development of metastases, new tumours, and mortality will be updated using hospital records. The HRQoL for long-term survivors will be assessed with the EORTC QLQ-C30 and QLQ-CR29 questionnaires. An analysis of global and specific survival (competitive risk models) will be performed. Relative survival will be estimated and mixture cure models will be applied. Finally, HRQoL will be analysed through multivariate regression models. Discussion We expect the results from this study to help us to more accurately determine the long-term survival of CRC, identify the needs and clinical situation of long-term CRC survivors, and could be used to propose new models of care for the follow-up of CRC patients.

Long-Term Prognosis of Monoarthritis: A Follow-up Study

1983 ◽  
Vol 12 (4) ◽  
pp. 374-376 ◽  
Author(s):  
K. Kaarela ◽  
S. Tiitinen ◽  
R. Luukkainen
Keyword(s):  
Follow Up Study ◽  
Long Term Prognosis

scholarly journals Long-term prognosis for neck-shoulder pain and disorders: a 14-year follow-up study

2017 ◽  
Vol 75 (2) ◽  
pp. 90-97 ◽  
Author(s):  
Emma Lise Thorlund Jakobsen ◽  
Karin Biering ◽  
Anette Kærgaard ◽  
Annett Dalbøge ◽  
Johan Hviid Andersen
Keyword(s):  
Shoulder Pain ◽  
Physical Functioning ◽  
Sewing Machine ◽  
Follow Up Study ◽  
Machine Operators ◽  
Shoulder Disorders ◽  
Long Term Prognosis ◽  
The Impact

ObjectivesThe long-term prognosis for neck-shoulder pain and disorders and the impact of shoulder exposure among former sewing machine operators were investigated in a 14-year follow-up study.MethodsInformation on neck-shoulder pain and disorders was collected by questionnaire and clinical examination at baseline in 243 female sewing machine operators and by questionnaire 14 years later. During follow-up, information on comorbidity and job exposures was obtained from registers and by linking register-based D-ISCO 88 codes with a job exposure matrix. Logistic regression analyses were performed to examine associations between neck-shoulder pain and disorders at baseline and neck-shoulder pain and physical functioning at follow-up.ResultsWe found an association between neck-shoulder disorders at baseline and neck-shoulder pain at follow-up (OR 5.9;95% CI 1.9 to 17.7), and between neck-shoulder pain at baseline and neck-shoulder pain at follow-up (OR 8.2;95% CI 3.5 to 19.2). Associations between neck-shoulder disorders and pain at baseline and limited physical functioning at follow-up had ORs of 5.0 (95% CI 1.5 to 16.1) and 2.2 (95% CI 1.1 to 4.6), respectively. In women still working in 2008, the association between neck-shoulder pain in 1994 and in 2008 seemed to be stronger for those in jobs with high job shoulder exposure.ConclusionsThe results suggest a long-term adverse prognosis for neck-shoulder pain. High job shoulder exposure can worsen this prognosis for those who continue working. This knowledge could influence the counselling given to similar workers and emphasises the need to prevent neck-shoulder pain.

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