Vulvar Paget's disease with underlying adenocarcinoma simulating breast carcinoma: case report and review of the literature

2004 ◽  
Vol 14 (5) ◽  
pp. 1012-1017 ◽  
Author(s):  
S. Ohira ◽  
K. Itoh ◽  
K. Osada ◽  
K. Oka ◽  
A. Suzuki ◽  
...  
1988 ◽  
Vol 74 (2) ◽  
pp. 183-190 ◽  
Author(s):  
Pietro Muretto ◽  
Vincenzo Polizzi ◽  
M. Pia Staccioli

A case of Paget's disease and gynecomastia in a 70-year-old man is reported. Paget's disease was connected to an intraductal carcinoma, and the immunohistochemical study revealed similar positivity for cytokeratin A, carcinoembryonic antigen and epithelial membrane antigen in Paget cells and intraductal neoplastic cells whereas Paget cells resulted negative for cytokeratin B and C. The study using monoclonal anti-cytokeratin A (35 βH11), B (34 βE12) and C (34 βB4) could represent a good tool, supporting the theory of a ductal origin of Paget cells. A review of the literature has shown the rarity of Paget's disease in the male breast and revealed only two previous reports with an associated gynecomastia, in 2 patients with Klinefelter's syndrome and infiltrating breast carcinoma.


2017 ◽  
Vol 213 (11) ◽  
pp. 1454-1456 ◽  
Author(s):  
Justine S. Broecker ◽  
Charles W. Sewell ◽  
Bahig M. Shehata ◽  
Bahar Memis ◽  
Nazmi V. Adsay ◽  
...  

2015 ◽  
Vol 2 (4) ◽  
Author(s):  
Ahmet Rencüzoğulları ◽  
Alexis K. Okoh ◽  
Orçun Yalav ◽  
Arbil Acıkalın ◽  
Gurhan Sakman ◽  
...  

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