scholarly journals Virological analysis and phenotypic characterization of peripheral blood lymphocytes of hepatitis C virus-infected patients with and without mixed cryoglobulinaemia

2006 ◽  
Vol 143 (2) ◽  
pp. 288-296 ◽  
Author(s):  
D. Sansonno ◽  
G. Lauletta ◽  
M. Montrone ◽  
F. A. Tucci ◽  
L. Nisi ◽  
...  
Keyword(s):  
Hepatitis C Virus ◽  
Hepatitis C ◽  
Peripheral Blood ◽  
Peripheral Blood Lymphocytes ◽  
Phenotypic Characterization ◽  
Blood Lymphocytes ◽  
Mixed Cryoglobulinaemia

ELISPOT Analysis of Hepatitis C Virus Protein-Specific IFN-γ-Producing Peripheral Blood Lymphocytes in Infected Humans with and without Cirrhosis

2001 ◽  
Vol 99 (2) ◽  
pp. 232-240 ◽  
Author(s):  
Donald D. Anthony ◽  
Anthony B. Post ◽  
Hernan Valdez ◽  
Darrell L. Peterson ◽  
Madeleine Murphy ◽  
...  
Keyword(s):  
Hepatitis C Virus ◽  
Hepatitis C ◽  
Peripheral Blood ◽  
Peripheral Blood Lymphocytes ◽  
Virus Protein ◽  
Blood Lymphocytes ◽  
Ifn Γ

Hepatitis C virus antibody secretion in vitro by peripheral blood lymphocytes

1992 ◽  
Vol 14 (1) ◽  
pp. 112-117 ◽  
Author(s):  
H. Löhr ◽  
B. Fleischer ◽  
G. Michel ◽  
S. Rossol ◽  
G. Hess ◽  
...  
Keyword(s):  
Hepatitis C Virus ◽  
Hepatitis C ◽  
Peripheral Blood ◽  
Peripheral Blood Lymphocytes ◽  
Virus Antibody ◽  
Blood Lymphocytes ◽  
Hepatitis C Virus Antibody ◽  
Antibody Secretion

scholarly journals Increased Migratory and Activation Cell Markers of Peripheral Blood Lymphocytes in an Experimental Model of Nephrotic Syndrome

2015 ◽  
Vol 2015 ◽  
pp. 1-11 ◽  
Author(s):  
Wagner de Fátima Pereira ◽  
Gustavo Eustáquio Alvim Brito-Melo ◽  
Cláudia Martins Carneiro ◽  
Dirceu de Sousa Melo ◽  
Karine Beatriz Costa ◽  
...  
Keyword(s):  
Nephrotic Syndrome ◽  
Peripheral Blood ◽  
Tissue Injury ◽  
Serum Levels ◽  
Peripheral Blood Lymphocytes ◽  
Phenotypic Characterization ◽  
Blood Collection ◽  
Blood Leukocytes ◽  
Male Adult

The present study aimed to evaluate the expression of CD80 and CD18 in subpopulations of peripheral blood leukocytes and oxidative kidney damage in rats with nephrotic syndrome (NS) induced by doxorubicin (Dox) in comparison to control animals at different time points. Male adult Wistar rats were submitted to 24-hour urine and blood collection for biochemical and immunological analysis at 7, 14, 21, and 28 days after Dox injection. After euthanasia, the kidneys were removed for histological analysis and the evaluation of oxidative stress. The phenotypic characterization of leukocytes was performed using flow cytometry. Dox-injected animals exhibited increased CD18 expression in cytotoxic T lymphocytes, NK cells, and monocytes and high CD80 expression in monocytes. Kidney oxidative damage was positively correlated with CD80 expression in monocytes and serum levels of creatinine. These results suggest that phagocytic and cytotoxic cells are preferentially recruited to the tissue injury site, which may contribute to kidney dysfunction in this animal model of NS. The blockade of integrin and costimulatory molecules may provide new therapeutic opportunities for NS.

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