Malignancy in giant cell tumour of bone: is there a reproducible histological threshold? A study of three giant cell tumours with worrisome features

AbstractAn unusual skull base tumour is presented. Intraoperative smears made the diagnosis and dictated a change in surgical strategy. Giant-cell tumours of the sphenoid bone are discussed, together with current management.

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Silastic Replacement of Metacarpal after Resection of Giant Cell Tumour. A Case Report

Journal of Hand Surgery (European Volume) ◽

10.1016/j.jhsb.2004.01.007 ◽

2004 ◽

Vol 29 (4) ◽

pp. 402-405 ◽

Cited By ~ 11

Author(s):

A. CHATTERJEE ◽

D. B. DHOLAKIA ◽

S. V. VAIDYA

Keyword(s):

Case Report ◽

Giant Cell ◽

Giant Cell Tumour ◽

Cell Tumour ◽

Benign Lesions ◽

Reconstructive Procedures ◽

Metacarpal Head ◽

Giant Cell Tumours ◽

Silastic Prosthesis ◽

Almost All

Giant cell tumours are aggressive lesions, albeit benign. Lesions in the hand, especially those arising from metacarpals require resection with adequate margins and definitive structural reconstruction to ensure preservation of hand architecture, function and cosmesis. Almost all the described reconstructive procedures require a stump of tumour free metacarpal base after resection, for reconstruction of the metacarpal. This report describes replacement of the entire metacarpal with a silastic prosthesis, in a case of giant cell tumour involving the entire metacarpal head and shaft to within 7 mm of the base.

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Giant cell tumour of hand bones: outcomes of treatment

Journal of Hand Surgery (European Volume) ◽

10.1177/17531934211007820 ◽

2021 ◽

pp. 175319342110078

Author(s):

Ajay Puri ◽

Rohit Rajalbandi ◽

Ashish Gulia

Keyword(s):

Giant Cell ◽

Giant Cell Tumour ◽

Treatment Options ◽

Rare Condition ◽

Asian Population ◽

Cell Tumour ◽

Level Of Evidence ◽

Hand Bones ◽

Giant Cell Tumours ◽

Treatment Morbidity

The purpose of this study was to report the incidence of giant cell tumour of the hand bones in an Asian population, document treatment options and report outcomes of treatment. Of 698 giant cell tumours of bone that underwent surgery between January 2011 and December 2020 at our institute, only 22 (3%) were in the hand. Fourteen occurred in the metacarpals, eight in the phalanges. Fifteen were primary tumours and seven had recurrent disease. Twenty lesions had an associated soft tissue component. Two patients treated for primary disease and one who had been treated for recurrence had local recurrence. Recurrence occurred in two of nine patients treated with curettage, one of three with resection and none of five with ray or digit amputation. Both curettage and resection/amputation are acceptable treatment options for the rare condition of giant cell tumour of bone in the hand, with a need to individualize treatment decisions based on the site and extent of disease to minimize treatment morbidity while maximizing disease control. Level of evidence: IV

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Recurrent Metacarpal Giant Cell Tumour Treated by En Bloc Resection and Metatarsal Transfer

Journal of Hand Surgery (European Volume) ◽

10.1016/s0266-7681(98)80197-6 ◽

1998 ◽

Vol 23 (2) ◽

pp. 275-278 ◽

Cited By ~ 16

Author(s):

J. PARDO-MONTANER ◽

A. PINA-MEDINA ◽

M. BARCELO-ALCAIÑIZ

Keyword(s):

Giant Cell ◽

Giant Cell Tumour ◽

En Bloc Resection ◽

Bloc Resection ◽

Cell Tumour ◽

En Bloc ◽

Giant Cell Tumours ◽

Risk Of Malignancy

Recurrent giant-cell tumours of bone have a higher risk of malignancy than primary giant-cell tumours of bone, and giant-cell tumours of bone in the hand are more likely to recur than those that arise elsewhere. Therefore, en bloc resection and reconstruction, or amputation, have been the accepted treatments for recurrent giant-cell tumours of bone in the hand. We describe two cases of successful transplantion of a metatarsal to a metacarpal, which was the site of a recurrent giant-cell tumour. The patients had satisfactory results 3 years later without problems in the foot. En bloc resection of the tumour and reconstruction with an autograft should be considered in the treatment of recurrent giant cell tumour of the hand.

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Giant cell tumour of the hyoid – first reported case

The Journal of Laryngology & Otology ◽

10.1017/s0022215100144500 ◽

1999 ◽

Vol 113 (6) ◽

pp. 566-568 ◽

Cited By ~ 1

Author(s):

D. J. Commins ◽

S. O'Malley ◽

N. A. Athanasou ◽

S. Jalloh

Keyword(s):

Head And Neck ◽

Giant Cell ◽

Hyoid Bone ◽

Giant Cell Tumour ◽

Weight Bearing ◽

Cell Tumour ◽

Long Bones ◽

Giant Cell Tumours

AbstractGiant cell tumours of bone are most commonly found in the epiphyses of weight-bearing long bones. They are rarely found in the head and neck and only 17 cases involving the laryngeal framework have been reported. To date, there have been no reports of a giant cell tumour arising from the hyoid bone. We present such a case which presented as a lump overlying the greater cornu of the hyoid, review the literature and discuss the management of this locally aggressive tumour.

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Giant Cell Tumours of the Hand

Journal of Hand Surgery (European Volume) ◽

10.1016/s0266-7681(96)80161-6 ◽

1996 ◽

Vol 21 (5) ◽

pp. 683-687 ◽

Cited By ~ 15

Author(s):

B. K. S. SANJAY ◽

G. A. RAJ ◽

D. A. YOUNGE

Keyword(s):

Giant Cell ◽

Giant Cell Tumour ◽

En Bloc Resection ◽

Bloc Resection ◽

Cell Tumour ◽

Fibular Graft ◽

En Bloc ◽

Giant Cell Tumours ◽

En Bloc Excision ◽

Bloc Excision

A study of seven cases of giant cell tumours of the hand is reported. All tumours were treated by an en bloc excision of the tumour or by whole ray resection. En bloc resection of the tumour and reconstruction with a fibular graft where necessary should be considered as the treatment of choice in giant cell tumour of the hand.

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