Studies on the neuroexcitotoxin β-N-oxalo-L-α, β-diaminopropionic acid and its isomer α-N-oxalo-L-α, βdiaminopropionic acid from the root of Panax species

2009 ◽  
Vol 47 (1-2) ◽  
pp. 42-46 ◽  
Author(s):  
YI-CHENG LONG ◽  
YUN-HCA YE ◽  
QI-YI XING
Keyword(s):  
Panax Species ◽  
Diaminopropionic Acid

Characterization of an l-α,β-diaminopropionic acid polymer with comb-like structure isolated from a poly(ε-l-lysine)-producing Streptomyces sp.

2021 ◽  
Vol 105 (8) ◽  
pp. 3145-3157
Author(s):  
Munenori Takehara ◽  
Masayuki Saimura ◽  
Haruka Inaba ◽  
Yoshinao Kato ◽  
Shogo Muro ◽  
...  
Keyword(s):  
Streptomyces Sp ◽  
Diaminopropionic Acid

scholarly journals OPTICAL ENANTIOMORPHS OF α,β-DIAMINOPROPIONIC ACID

1952 ◽  
Vol 198 (1) ◽  
pp. 335-342 ◽  
Author(s):  
Sanford M. Birnbaum ◽  
Robert J. Koegel ◽  
Shou-Cheng J. Fu ◽  
Jesse P. Greenstein
Keyword(s):  
Diaminopropionic Acid

scholarly journals Novel Cell Permeable Polymers of N-Substituted L-2,3-Diaminopropionic Acid (DAPEGs) and Cellular Consequences of Their Interactions with Nucleic Acids

2021 ◽  
Vol 22 (5) ◽  
pp. 2571
Author(s):  
Anita Romanowska ◽  
Katarzyna Węgrzyn ◽  
Katarzyna Bury ◽  
Emilia Sikorska ◽  
Aleksandra Gnatek ◽  
...  
Keyword(s):  
Cell Membrane ◽  
Plasmid Dna ◽  
Main Chain ◽  
Cell Permeability ◽  
Binding Ability ◽  
Transfection Efficacy ◽  
Polycationic Polymers ◽  
Diaminopropionic Acid ◽  
Dsdna Binding ◽  
Micromolar Range

The present study aimed to synthesize novel polycationic polymers composed of N-substituted L-2,3-diaminopropionic acid residues (DAPEGs) and investigate their cell permeability, cytotoxicity, and DNA-binding ability. The most efficient cell membrane-penetrating compounds (O2Oc-Dap(GO2)n-O2Oc-NH2, where n = 4, 6, and 8) showed dsDNA binding with a binding constant in the micromolar range (0.3, 3.4, and 0.19 µM, respectively) and were not cytotoxic to HB2 and MDA-MB-231 cells. Selected compounds used in the transfection of a GFP plasmid showed high transfection efficacy and minimal cytotoxicity. Their interaction with plasmid DNA and the increasing length of the main chain of tested compounds strongly influenced the organization and shape of the flower-like nanostructures formed, which were unique for 5/6-FAM-O2Oc-[Dap(GO2)]8-O2Oc-NH2 and typical for large proteins.

scholarly journals Towards authentication of Korean ginseng-containing foods: Differentiation of five Panax species by a novel diagnostic tool

LWT ◽  
2021 ◽  
pp. 112211
Author(s):  
Liliana Grazina ◽  
Joana S. Amaral ◽  
Joana Costa ◽  
Isabel Mafra
Keyword(s):  
Diagnostic Tool ◽  
Panax Species ◽  
Korean Ginseng
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