A comparison of endoscopic and capsule small intestinal biopsy techniques in children with upper gastrointestinal disorders

1996 ◽  
Vol 32 (3) ◽  
pp. 255-256 ◽  
Author(s):  
MA ELTUMI ◽  
PS ONG ◽  
ND FRANCIS ◽  
MJ BRUETON
Keyword(s):  
Intestinal Biopsy ◽  
Gastrointestinal Disorders ◽  
Small Intestinal Biopsy ◽  
Small Intestinal ◽  
Upper Gastrointestinal

Determination of enteroglucagon in plasma for detection of celiac disease in children.

1984 ◽  
Vol 30 (1) ◽  
pp. 77-80 ◽  
Author(s):  
A F Kilander ◽  
L Stenhammar ◽  
G Lindstedt ◽  
P A Lundberg
Keyword(s):  
Celiac Disease ◽  
Intestinal Biopsy ◽  
Gastrointestinal Disorders ◽  
Small Intestinal Biopsy ◽  
The Mean ◽  
Small Intestinal ◽  
Untreated Celiac Disease ◽  
Selection Of Patients ◽  
Selection Of

Abstract To evaluate the plasma enteroglucagon assay as a test for the detection of celiac disease, we have determined basal and postprandial concentrations of enteroglucagon in plasma of children who underwent small-intestinal biopsy because of suspected celiac disease. In the 14 children with untreated celiac disease both basal [81 (SD 33) pmol/L] and postprandial [129 (SD 26) pmol/L] concentrations of enteroglucagon were significantly higher (p less than 0.001) than in the 45 children with other gastrointestinal disorders [24 (SD 9) pmol/L, and 50 (SD 22) pmol/L, respectively] and in the 15 children without gastrointestinal disorders [14 (SD 10) pmol/L, and 35 (SD 8) pmol/L, respectively]. All children with celiac disease had either basal or postprandial plasma enteroglucagon concentrations exceeding the mean + 2 SD of the results for the children with other gastrointestinal disorders. Eight of 10 children with celiac disease in whom both concentrations were measured had increased values for both. In our study the sensitivity for detection of celiac disease was 100% and the specificity 97%. Evidently determination of plasma enteroglucagon concentration is effective in diagnosing celiac disease, thereby improving the selection of patients for small-intestinal biopsy.

Intractable Diarrhea: Value of the Small Intestinal Biopsy

PEDIATRICS ◽  
1981 ◽  
Vol 68 (3) ◽  
pp. 470-471
Author(s):  
William J. Byrne ◽  
Arthur R. Euler
Keyword(s):  
Small Bowel ◽  
Nutritional Support ◽  
Mucosal Injury ◽  
Intestinal Biopsy ◽  
Intractable Diarrhea ◽  
Small Bowel Biopsy ◽  
Entire Small Intestine ◽  
Small Intestinal Biopsy ◽  
Close Proximity ◽  
Small Intestinal

In summarizing their article on intractable diarrhea of infancy Rossi et al1 stated, "a small bowel biopsy is useful in assessing the degree of injury present and guiding nutritional support." We concur that the small bowel biopsy is useful in assessing mucosal injury but has certain limitations. The authors used the Crosby-Krugler capsule, which obtains two small pieces of tissue, in close proximity. This limits the sensitivity of the technique as the specimens are not necessarily representative of the mucosal state of the entire small intestine nor do they allow exclusion of a patchy villous lesion.2

Sign in / Sign up

Export Citation Format

Share Document